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Application method of lactococcus lactis in treating intestinal diseases

A technology for Lactococcus lactis and intestinal diseases, applied in the field of biomedicine, can solve problems such as body injury, taking advantage of weakness, and decreased resistance

Inactive Publication Date: 2015-03-04
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Probiotics and our gastrointestinal mucosa have built an ecological barrier to resist and fight against various foreign pathogenic microorganisms. The body's resistance will decline, and some originally harmless bacteria may take advantage of the weak point to cause damage to the body and cause the intestinal mucosal barrier function to decline

Method used

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Examples

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Effect test

example 1

[0012] Clinically, there are many reasons for intestinal flora imbalance, intestinal barrier function damage, intestinal inflammation, intestinal tumors and other diseases. Lactococcus lactis can effectively reduce or improve the imbalance of intestinal flora, control the normal intestinal environment, and have a protective effect on the intestinal environment. Lactococcus lactis can treat intestinal diseases, especially in enteritis, intestinal tumors and other diseases The effect is better. The treatment method is to chew lactobacillus tablets orally, 3.6 grams / time, three times a day.

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Abstract

The invention belongs to the technical field of biological medicines and in particular relates to an application method of lactococcus lactis in treating intestinal diseases, and is mainly used for treating the intestinal diseases including enteritis and intestinal tumors. The lactococcus lactis does not belong to normal microbiota of humans and animals and can not be colonized in an oral cavity or a gastrointestinal tract, so that immune tolerance caused by long-term simulation is avoided to a certain extent; in addition, the lactococcus lactis is probiotics in the gastrointestinal tract and can not attack intestinal mucosa without causing strong immune response, thus being very suitable for treating the intestinal diseases including the enteritis and the intestinal tumors.

Description

technical field [0001] The invention discloses an application method of Lactococcus lactis in treating intestinal diseases, and belongs to the field of biomedicine. Background technique [0002] Lactic acid bacteria (lactis acid bacteria, LAB) is a group of Gram-positive bacteria that can ferment carbohydrates and produce lactic acid in large quantities, including more than a dozen genera such as Lactococcus, Lactobacillus, and Bifidobacterium. Lactococcus lactis is a kind of beneficial microorganisms long-term used in the food fermentation industry. This food-grade microorganism can withstand the test of gastrointestinal fluid and survive in the human body for 2 to 3 days. It does not attack the intestinal mucosa itself and does not cause infection. The most promising application is Lactococcus lactis as a live carrier to deliver therapeutic proteins or antigens to the mucosal surface, and then induce both mucosal and systemic immunity. Lactococcus lactis is an ideal choic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/744A61P1/00A61P35/00
CPCA61K35/744A61K38/208
Inventor 范红斌庞庆丰杜斌陈俊良
Owner JIANGNAN UNIV
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