A kind of orthopedic adhesive and preparation method thereof

An adhesive and orthopedic technology, applied in surgical adhesives, applications, medical science, etc., can solve problems such as medical adhesives not appearing, and achieve good comprehensive performance

Active Publication Date: 2016-08-03
BEIJING ALLGENS MEDICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] However, medical adhesives that can fully meet the ideal requirements have not yet appeared.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] An orthopedic adhesive, in parts by weight, comprising the following components: 10 parts of calcium silicate, 10 parts of potassium dihydrogen phosphate, 5 parts of sodium alginate, 20 parts of magnesium oxide, 5 parts of calcium carbonate, 3 parts of kaolin , 10 parts of propylene glycol, 5 parts of glycerin, 5 parts of sodium borate and 30 parts of deionized water.

[0026] The preparation method is as follows:

[0027] (1) Weigh each raw material by weight;

[0028] (2) Calcium silicate, potassium dihydrogen phosphate, magnesium oxide, calcium carbonate and kaolin are respectively ball milled to powders with a particle size of less than 10 μm, and then the five powders are uniformly mixed to obtain a mixture for use;

[0029] (3) Add sodium alginate, propylene glycol, glycerin, and sodium borate to deionized water in sequence, stir evenly to obtain a clear solution, and slowly add the mixture obtained in step (1) to the clear solution under constant stirring. Ultrasound fo...

Embodiment 2

[0031] An orthopedic adhesive, in parts by weight, comprising the following components: 20 parts of calcium silicate, 20 parts of potassium dihydrogen phosphate, 10 parts of sodium alginate, 35 parts of magnesium oxide, 7 parts of calcium carbonate, and 5 parts of kaolin , 12 parts of propylene glycol, 8 parts of glycerin, 8 parts of sodium borate and 38 parts of deionized water.

[0032] The preparation method is as follows:

[0033] (1) Weigh each raw material by weight;

[0034] (2) Calcium silicate, potassium dihydrogen phosphate, magnesium oxide, calcium carbonate and kaolin are respectively ball milled to powders with a particle size of less than 10 μm, and then the five powders are uniformly mixed to obtain a mixture for use;

[0035] (3) Add sodium alginate, propylene glycol, glycerin, and sodium borate to deionized water in sequence, stir evenly to obtain a clear solution, and slowly add the mixture obtained in step (1) to the clear solution under constant stirring. Ultrasou...

Embodiment 3

[0037] An orthopedic adhesive, in parts by weight, comprising the following components: 125 parts of calcium silicate, 25 parts of potassium dihydrogen phosphate, 12 parts of sodium alginate, 38 parts of magnesium oxide, 8 parts of calcium carbonate, and 6 parts of kaolin , 13 parts of propylene glycol, 9 parts of glycerin, 10 parts of sodium borate and 42 parts of deionized water.

[0038] The preparation method is as follows:

[0039] (1) Weigh each raw material by weight;

[0040] (2) Calcium silicate, potassium dihydrogen phosphate, magnesium oxide, calcium carbonate and kaolin are respectively ball milled to powders with a particle size of less than 10 μm, and then the five powders are uniformly mixed to obtain a mixture for use;

[0041] (3) Add sodium alginate, propylene glycol, glycerin, and sodium borate to deionized water in sequence, stir evenly to obtain a clear solution, and slowly add the mixture obtained in step (1) to the clear solution under constant stirring. Ultras...

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Abstract

The invention provides an adhesive for the department of orthopaedics and a preparation method of the adhesive. The adhesive comprises the following components: silicate, phosphate, sodium alginate, magnesium oxide, calcium carbonate, kaolin, propylene glycol, glycerin, a retarder and deionized water. The preparation method comprises the following steps: weighing all the raw materials in parts by weight; performing ball-milling on silicate, phosphate, magnesium oxide, calcium carbonate and kaolin into powders, and uniformly mixing the five powders to obtain a mixture; sequentially adding sodium alginate, propylene glycol, glycerin and the retarder in the deionized water, uniformly stirring to obtain a settled solution, slowly adding the mixture in the settled solution under the condition of continuously stirring, and performing ultrasound at the room temperature to obtain the adhesive. The adhesive for the department of orthopaedics, prepared by the preparation method, is high in comprehensive performance, finally sets for about 60 minutes, has the compressive strength of 54.6-58.3 MPa, can meet the clinical application requirement, and is suitable for the treatment of osteoporosis and the fracture fixation and treatment in the department of orthopaedics and the spine surgery.

Description

Technical field [0001] The invention relates to the field of adhesives, in particular to an adhesive for orthopedics and a preparation method thereof. Background technique [0002] With the advancement of the medical level, the clinical requirements for surgical operations and auxiliary materials are getting higher and higher, and the improvement of clinical requirements has promoted the research and development of medical adhesives. Medical adhesives refer to preparations, materials or substances that can be adhered to or cause adhesion between surfaces in medical applications. They are mainly used for local adhesion and repair of organs or tissues, auxiliary hemostasis of traditional sutures, Tooth repair, bone or joint integration and positioning technology fields. Compared with traditional methods such as suture and nailing, the use of medical adhesives can effectively shorten the operation time and reduce the pain of patients. Therefore, medical adhesives are increasingly ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L24/08A61L24/02
Inventor 李东航徐勤霞李苏杨
Owner BEIJING ALLGENS MEDICAL SCI & TECH
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