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Acne-removing composition and preparation method thereof

A composition and anti-acne technology, which is applied in the field of anti-acne composition and its preparation, can solve the problems of slow onset of action, long cycle, and troubles for consumers, and achieve the effects of regulating oil balance, mild nature, and inhibiting the decline of sebaceous gland overflow rate Effect

Inactive Publication Date: 2015-03-25
金日制药(中国)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are already many patents and products of acne-reducing cosmetics with plant active ingredients, the slow onset and long cycle are still problems that plague consumers.

Method used

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  • Acne-removing composition and preparation method thereof
  • Acne-removing composition and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0049] (1) Preparation of sodium hyaluronate solution: at 25°C, add 0.01 parts by mass of sodium hyaluronate to 1 part by mass of water and soak for 30 minutes, then stir at 200 rpm / min until completely transparent;

[0050] (2) Prepare sodium hydroxide solution: dissolve 0.05 parts by mass of sodium hydroxide in 0.5 parts by mass of deionized water and stir to dissolve;

[0051] (3) Preparation of menthol solution: Heat 0.1 parts by mass of menthol, 2 parts by mass of 1,3-butanediol and 3 parts by mass of propylene glycol to 45°C, stir at 300 rpm / min until completely transparent, add 0.5 parts by mass of PEG-40 Hydrogenated castor oil, stir evenly, add 5 parts by mass of deionized water, continue to stir until completely dissolved and transparent;

[0052] (4) Prepare Beta-Hydroxyde ACSD solution: add 0.3 parts by mass of Beta-Hydroxyde ACSD to 3 parts by mass of deionized water, stir at 200 rpm / min until completely dissolved and transparent;

[0053] (5) Preparation of hydr...

Embodiment 2

[0065] (1) Prepare sodium hyaluronate solution: at 25°C, add 0.03 parts by mass of sodium hyaluronate to 2 parts by mass of water and soak for 60 minutes, then stir at 300 rpm / min until completely transparent;

[0066] (2) Prepare sodium hydroxide solution: dissolve 0.06 parts by mass of sodium hydroxide in 0.6 parts by mass of deionized water, stir and dissolve;

[0067] (3) Preparation of menthol solution: Heat 0.15 parts by mass of menthol, 5 parts by mass of 1,3-butanediol and 8 parts by mass of propylene glycol to 50°C, stir at 500 rpm / min until completely transparent, add 0.8 parts by mass of PEG-40 Hydrogenated castor oil, stir evenly, add 8 parts by mass of deionized water, continue to stir until completely dissolved and transparent;

[0068] (4) Prepare Beta-Hydroxyde ACSD solution: add 0.8 parts by mass of Beta-Hydroxyde ACSD to 5 parts by mass of deionized water, stir at 300 rpm / min until completely dissolved and transparent;

[0069] (5) Preparation of hydroxyethy...

Embodiment 3

[0081] (1) Preparation of sodium hyaluronate solution: at 25°C, add 0.02 parts by mass of sodium hyaluronate to 1.5 parts by mass of water and soak for 45 minutes, then stir at 250 rpm / min until completely transparent;

[0082] (2) Prepare sodium hydroxide solution: dissolve 0.055 parts by mass of sodium hydroxide in 0.55 parts by mass of deionized water, stir and dissolve;

[0083] (3) Preparation of menthol solution: Heat 0.125 parts by mass of menthol, 3.5 parts by mass of 1,3-butanediol and 5.5 parts by mass of propylene glycol to 47.5°C, stir at 400 rpm / min until completely transparent, add 0.65 parts by mass of PEG-40 Hydrogenated castor oil, stir evenly, add 6.5 parts by mass of deionized water, continue stirring until completely dissolved and transparent;

[0084] (4) Prepare Beta-Hydroxyde ACSD solution: add 0.65 parts by mass of Beta-Hydroxyde ACSD to 4 parts by mass of deionized water, stir at 250 rpm / min until completely dissolved and transparent;

[0085] (5) Pre...

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Abstract

The invention discloses an acne-removing composition and a preparation method thereof. The acne-removing composition can be absorbed by skins faster compared with an emulsion preparation so as to take the function to the maximum extent. The function of comprehensively removing acnes is achieved by means of improving the moisturizing effect of the skins, adjusting the grease balance of the skins, inhibiting hypersecretion of sebum and inhibiting reproduction of propionibacterium acnes as well as by virtue of interaction of anti-inflammatory action and acne removal. The pH of the acne-removing composition is 4.5-5.5 (10% aqueous solution) which is faintly acid, and the acne-removing composition is mild in property and does not irritate the skins, and meanwhile, the effects of macromolecular salicylic acid and a composite plant acne-removing preparation are more obvious.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to an acne-removing composition and a preparation method thereof. Background technique [0002] Acne, known as "acne" in traditional Chinese medicine, commonly known as acne, is a chronic inflammatory skin disease that occurs in the pilosebaceous glands. Acne is a global disease. It is a common and frequently-occurring disease in dermatology. It mainly occurs in the face, chest, shoulders and feet where the sebaceous glands are densely distributed and the sebaceous glands are exuberantly secreted. Acne lesions manifest as whiteheads and blackheads, papules, pustules, nodules and cysts, and patients may even form sunken or hypertrophic scars. Acne seriously affects the appearance and quality of life of patients. Delayed or wrong treatment will lead to aggravated infection and even scars Legacy. [0003] According to Western medicine theory, it is generally believed th...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61Q19/00A61P17/10
Inventor 周丽娟王英吴晶邵家用钟勤雄占晓波林占亮
Owner 金日制药(中国)有限公司
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