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Traditional Chinese medicine composition for treating anaphylactoid purpura as well as preparation method and application of traditional Chinese medicine composition

A technology for allergic purpura and composition, which is applied in the directions of drug combination, allergic diseases, pharmaceutical formulations, etc., can solve problems such as lack of finished medicines, and achieve the effects of no toxic side effects, exact curative effect, and reasonable design.

Inactive Publication Date: 2015-03-25
NANJING HUAKUANG INFORMATION CONSULTING CENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is a lack of truly effective medicines in the market

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation Embodiment 1

[0013] 1. Preparation Example 1: Take 20g of Dahehong, 15g of Tonghammer japonica, 16g of Eupatorium, 25g of Salvia miltiorrhiza, 15g of raw land, 12g of paeonol, 10g of psyllium, and 20g of rush. The amount of water is 10 times the weight of the medicinal material, decocted for 2 hours, combined the decoction, concentrated to 65 ° C, the relative density is 1.10, add ethanol to make the volume percentage of the alcohol content reach 65%, stir, stand still, filter, and decompress the filtrate When concentrated to 65°C, the relative density is 1.20 and ethanol is recovered, and the concentrated solution is spray-dried. The spray-drying conditions are: the inlet air temperature is 100°C, the outlet air temperature is 80°C, the material temperature is 70°C, and the atomization pressure is 0.2 Mg Pa, spray speed is 5ml / s, add starch to make capsules.

preparation Embodiment 2

[0014] Preparation Example 2: Take 15g of Dahehong, 20g of Tonghammer Yudaicao, 12g of Eupatorium, 30g of Salvia miltiorrhiza, 10g of raw land, 16g of paeonol, 10g of plantago seed, and 25g of rush grass. 10 times the weight of the medicinal materials, decocted for 2 hours, combined the decoction, concentrated to 65 ° C, the relative density was 1.10, added ethanol to make the volume percentage of the alcohol content reach 65%, stirred, stood still, filtered, and the filtrate was concentrated under reduced pressure to At 65°C, the relative density is 1.20 and ethanol is recovered, and the concentrated solution is spray-dried. The spray-drying conditions are: the inlet air temperature is 100°C, the outlet air temperature is 80°C, the material temperature is 70°C, and the atomization pressure is 0.2 MPa. The spray speed is 5ml / s, starch is added, granulated and pressed into tablets to make tablets.

preparation Embodiment 3

[0015] Preparation Example 3: Take 25g of Dahehong, 10g of Tongmai Yudaicao, 18g of Eupatorium, 20g of Salvia miltiorrhiza, 20g of raw land, 8g of paeonol, 15g of plantago, and 15g of rush grass. 10 times the weight of the medicinal materials, decocted for 2 hours, combined the decoction, concentrated to 65 ° C, the relative density was 1.10, added ethanol to make the volume percentage of the alcohol content reach 65%, stirred, stood still, filtered, and the filtrate was concentrated under reduced pressure to At 65°C, the relative density is 1.20 and ethanol is recovered, and the concentrated solution is spray-dried. The spray-drying conditions are: the inlet air temperature is 100°C, the outlet air temperature is 80°C, the material temperature is 70°C, and the atomization pressure is 0.2 MPa. Spray speed is 5ml / s, add starch, granulate to make granules.

[0016] Two, the clinical trial data of the present invention to anaphylactoid purpura

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition for treating anaphylactoid purpura. The composition is prepared from the following medicinal raw materials in parts by weight: 15-25 parts of campylotropis hirtella, 10-20 parts of pratia nummularia, 12-18 parts of herba lycopi, 20-30 parts of salviae miltiorrhizae, 10-20 parts of radix rehmanniae recen, 8-16 parts of moutan bark, 10-15 parts of semen plantaginis and 15-25 parts of rush. The traditional Chinese medicine composition is capable of activating blood circulation to remove stasis, inducing diuresis and removing stagnation, and can be used for treating anaphylactoid purpura. The invention further discloses a preparation method and application of the traditional Chinese medicine composition.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating allergic purpura, a preparation method and an application. Background technique [0002] Henoch-Schonlein purpura, also known as Henoch-Schonlein purpura, is an allergic vasculitis that invades small arteries and capillaries of the skin and other organs, often accompanied by abdominal pain, arthralgia and kidney damage, but platelets do not decrease. It may be related to streptococcal infection, viral infection, drugs, food, insect bites, etc. The mechanism is due to immune complex deposition or IgE-mediated vascular injury. It has also been reported that the serum IgA of the patient is increased, and IgA is deposited in the skin small vessel wall and glomerular tissue of the skin lesions and non-lesions. Predominantly occurs in children and adolescents, may have fever, headache, arthralgia, general ma...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P37/08A61P7/04
CPCA61K36/48A61K9/1652A61K9/2059A61K9/4866A61K36/34A61K36/53A61K36/537A61K36/68A61K36/71A61K36/804A61K36/88A61K2236/331A61K2236/39A61K2236/51A61K2236/53
Inventor 陈军
Owner NANJING HUAKUANG INFORMATION CONSULTING CENT