Super-hydrophobic single-plate digital micro-droplet transport device, and manufacturing method thereof

Abstract

The invention discloses a super-hydrophobic single-plate digital micro-droplet transport device, and a manufacturing method thereof. The super-hydrophobic single-plate digital micro-droplet transport device comprises, from the bottom to the top, a substrate, electrodes, a medium layer, and a super-hydrophobic layer successively; the substrate is a glass or Si substrate; the electrodes are ITO glass electrodes, Au / Cr(Au / Ti) or Al / Cr(Al / Ti) thin film electrodes; and the super-hydrophobic layer is made of boron nitride nanotubes. The manufacturing method comprises following steps: step 1, the substrate is cleaned; step 2, the substrate is provided with the electrodes; step 3, the electrodes are provided with the medium layer via deposition; and step 4, the medium layer is coated with the boron nitride nanotube super-hydrophobic layer via spin coating. Advantages of the super-hydrophobic single-plate digital micro-droplet transport device are that: digital micro-fluidic chips are prepared via micro mechanical processing technology, structure is simple, operation is convenient, and it is beneficial for expansion of subsequent functions. The super-hydrophobic single-plate digital micro-droplet transport device is capable of reducing waste of precious samples, reducing driving voltage, maintaining biological activity of samples, increasing feasibility and practicality of experiments, and promoting smooth implementation of experiments of the bio-medical field; and integration with IC, and achieving of more functions are convenient.

Description

technical field [0001] The invention belongs to the technical field of digital microfluidics and the field of biomedicine, and relates to a novel micro-droplet transport device and a manufacturing method thereof, in particular to a super-hydrophobic single-polar plate digital micro-droplet transport device and its manufacture method. Background technique [0002] In the early 1990s, A.Manz first proposed the concept of a micro-total analysis system. Its goal is to miniaturize and integrate the basic operating units of samples in the fields of biomedicine and other fields into centimeter-level chips, so as to realize various Detection and analysis functions, so the micro-total analysis system is also called Lab on a Chip (Lab on a Chip). Lab-on-a-chip mainly includes two categories: microfluidic chips and biochips. Among them, microfluidic chips are further divided into continuous microfluidic chips and digital microfluidic chips. [0003] The target sample of a continuous...

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Problems solved by technology

It is undeniable that boron nitride nanotubes are also a superhydrophobic material, and its hydrophobic angle can be as high as 150°-160°, which is 30°-40° higher than that of traditional hydrophobic materials, and its dielectric constant is high. , which is undoubtedly very useful for reducing the contamination and waste of digital microfluidic devices and reducing the driving voltage of digital microfluidic devices, and there is no report in this regard

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