Cold-fever-treating granules and preparation method thereof

A technology for removing impurities in Ganmaotupyre granule and its preparation, which can solve the problems of unsatisfactory drug efficacy, shock in patients, and large side effects

Inactive Publication Date: 2015-04-29
HUBEI FUREN JINSHEN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the treatment of Western medicine is one-sided, and the side effects are large. Patients with allergic reactions may lead to shock and death
The use of Chinese herbal medicine to treat colds has been a research work, but the curative effect of the current medicine is not satisfactory

Method used

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  • Cold-fever-treating granules and preparation method thereof
  • Cold-fever-treating granules and preparation method thereof
  • Cold-fever-treating granules and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] A preparation process of Ganmao antipyretic granule is as follows:

[0040] ①. Finishing and processing process: remove impurities from 400g Folium Isatidis, wash slightly, cut into 8-10cm wide slices, dry, and the water content does not exceed 13%; remove impurities from 400g Radix Radix, rinse, moisten, cut into 1.3-1.5cm section, dry at 65°C, the water content does not exceed 15%; remove impurities from 200g of forsythia, and the water content does not exceed 10%; Cut into 1.3-1.5cm sections, dry at 65°C, and the water content should not exceed 15%;

[0041] ②. Decoction: Mix the four medicinal materials processed in step ①, add 10 times the amount of water to decoct twice, each time for 3 hours, control the decoction temperature at 95-100°C, pressure at 0.15-0.2MPa, The liquid output is 4 to 4.5 times of the total amount of medicinal materials, the decoction is combined, filtered, and transferred to a storage tank;

[0042] ③. Transfer the decoction in the storage...

Embodiment 2

[0053] A preparation process of Ganmao antipyretic granule is as follows:

[0054] ①. Finishing and processing process: remove impurities from 300g Folium Isatidis, wash slightly, cut into 7-9cm wide slices, dry, and the moisture does not exceed 13%; remove impurities from 300g Radix Radix, rinse, moisten, cut into pieces 1.1-1.3cm section, dry at 65°C, moisture not exceeding 15%; remove impurities from 120g forsythia, moisture not exceeding 10%; remove impurities from 100g ginseng, wash with water to clean the sediment, moisten thoroughly, cut into pieces Form into 1.2-1.5cm sections, dry at 65°C, and the water content should not exceed 15%;

[0055] ②. Decoction: Mix the four medicinal materials processed in step ①, add 6 times the amount of water to decoct twice, each time for 2 hours, control the decoction temperature at 95-100°C, pressure at 0.2-0.3MPa, The liquid output is 4 to 5 times of the total amount of medicinal materials, the decoction is combined, filtered, and ...

Embodiment 3

[0063] A preparation process of Ganmao antipyretic granule is as follows:

[0064] ①. Finishing and processing process: remove impurities from 330g Folium Isatidis, wash slightly, cut into 7-10cm wide slices, dry, and the water content does not exceed 13%; remove impurities from 350g Radix Radix, rinse, moisten, cut into 1.2-1.5cm section, dry at 65°C, moisture not exceeding 15%; remove impurities from 140g forsythia, moisture not exceeding 10%; remove impurities from 160g fist ginseng, wash with water and sand, moisten thoroughly, cut Cut into 1.1-1.4cm sections, dry at 65°C, and keep the water content not exceeding 15%;

[0065] ②. Decoction: Mix the four medicinal materials processed in step ①, add 8 times the amount of water to decoct twice, each time for 1.5 hours, control the decoction temperature at 95-100°C, pressure at 0.15-0.25MPa, The liquid output is 4 to 5 times of the total amount of medicinal materials, the decoction is combined, filtered, and transferred to a ...

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Abstract

The invention discloses cold-fever-treating granules and a preparation method thereof. The preparation method comprises the following steps: finishing and preparing 30-40% of folium isatidis, 30-40% of isatis root, 10-20% of fructus forsythiae and 10-20% of bistort rhizome, then adding water and decocting for twice while controlling the temperature, pressure, time, adding amount, solution discharge amount and times of the decoction, and then concentrating the decoction while controlling the temperature, pressure and solution charge amount during the concentration; then continuing to precipitate with ethanol, concentrating, precipitating with water, and concentrating into a paste with a weight which is not less than 12.5% of a raw medicine amount; crushing and sieving, drying, straightening and mixing, sub-packaging and packaging. The cold-fever-treating granules and the preparation method thereof disclosed by the invention have the following advantages: the prepared granules are sweet in taste, slightly bitter (without saccharose) and uniform, are capable of clearing away heat and toxic materials, and dispelling wind and relieving exterior syndrome, and are used for upper respiratory infection, acute tonsillitis, sphagitis, extrapelvic wind-heat, heat-toxin obstruction, fever and swollen sore throat; the production process is simple and easy to control, and only needs four medicinal materials.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and in particular relates to a Ganmao antipyretic granule for clearing away heat and detoxification, dispelling wind and relieving the exterior and a preparation method thereof. Background technique [0002] Fengreganmao is a common type of cold, which is caused by the appearance of wind-heat evil criminals and loss of lung energy. Symptoms include severe fever, mild wind, head bloating, sweating, sore throat, cough, sticky or yellow phlegm, yellow stuffy nose, thirsty drink, red tip of tongue, thin white yellowish fur. The etiology is caused by exogenous pathogenic factors and six evils, which are often transmitted by viruses. When the external function of the human body is weakened and the strain cannot be adjusted, it invades from the fur, mouth and nose, and the evil invades the lungs. Generally speaking, colds seldom spread and change, and the course of the disease is short and easy to hea...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/704A61K36/855A61K9/16A61P11/00A61P29/00A61P11/04
Inventor 曾希望黄军陆王翠娟曾浩石伟沈新伦
Owner HUBEI FUREN JINSHEN PHARMA
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