Cold stamping solid pharmaceutical composite hard tablet

Abstract

The invention relates to a cold-stamping composite hard tablet for solid medicine and belongs to the technical field of pharmaceutical packaging materials. The cold-stamping composite hard tablet for solid medicine of the invention comprises a polyamide layer, an aluminum foil layer and a polyvinyl chloride layer which are sequentially arranged, wherein a glue layer is arranged between the aluminum foil layer and the polyvinyl chloride layer. According to the invention, each surface of the aluminum foil layer comprises an aluminum phosphate film and a rough layer, the surface of the aluminum foil layer is coated with a polyurethane resin layer and the polyurethane resin layer is located between the aluminum foil layer and the polyamide layer; a maleic anhydride modified polyethylene layer and an acrylic acid modified polyethylene layer are orderly arranged between the polyamide layer and the aluminum foil layer; and adhesive layers are both arranged between the acrylic acid modified polyethylene layer and the polyurethane resin layer and between the aluminum foil layer and the polyurethane resin layer. According to the invention, the glue density of the glue layer is 4.9-5.1g / cm<3>, the thickness of the polyamide layer is 28-32 mu m, the thickness of the aluminum foil layer is 48-53 mu m, the thickness of the polyurethane resin layer is 52-58 mu m and the total thickness of the composite hard tablet is 140-143 mu m. The composite hard tablet of the invention has long service life and small vapor and oxygen transmittance.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical packaging materials, in particular to a cold stamping solid pharmaceutical composite hard tablet. Background technique [0002] In the existing pharmaceutical packaging industry, PVC blister and pharmaceutical PTP aluminum foil are used for heat-sealing packaging. PVC has performance defects such as blocking water vapor and oxygen, and the storage time of medicines, health products, and food is short, and the light transmission performance of PVC is not effective. Blocks ultraviolet rays, and is prone to aging under ultraviolet radiation, producing toxic gases. Although my country's pharmaceutical industry, health care products, and food industry have developed rapidly, and pharmaceutical packaging materials have also developed rapidly, the structure of the tropical-type cold-stamped composite hard sheet currently existing in the industry is a nylon layer (polyamide layer) and an aluminum f...

AI Technical Summary

Problems solved by technology

The aluminum foil produced by 3003 alloy has good punching performance, but because the content of Mn element in the alloy is too high, the grains are easy to grow during homogenization annealing, and the surface is inevitable when it is rolled to the thickness of the finished product. Coarse grain stripes will appear, affecting normal use

On the other hand, due to the characteristics of the 3003 alloy itself, the strength of the material is high, and the loss of rolling equipment and punching equipment is relatively large. At the same time, a large amount of copper and manganese metals need to be added, which increases the production cost of the enterprise.

Although the aluminum foil for tableware produced by 8011 alloy can overcome some shortcomings of 3003 alloy, because the content of alloy elements in 8011 alloy is low, but its performance is soft, it is not suitable for high-speed punching, and the punching depth is insufficient, and its application range is limited. very restrictive

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