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Pharmaceutical composition for treating chronic pharyngitis

A technology of chronic pharyngitis and composition, which is applied in the field of pharmaceutical composition for treating chronic pharyngitis, can solve problems such as inaccurate curative effect of chronic pharyngitis, and achieve the effect of improving drug efficacy and activity

Active Publication Date: 2018-02-02
XIAN BOAI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The curative effect of Western medicine on chronic pharyngitis is uncertain. Although the use of cautery can improve the sensation of foreign body in the pharynx, it often leads to dry throat and aggravated sore throat due to the destruction of glandular secretion of the mucous membrane and scar contracture. Treatment of chronic pharyngitis has its unique curative effect than western medicine

Method used

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  • Pharmaceutical composition for treating chronic pharyngitis
  • Pharmaceutical composition for treating chronic pharyngitis
  • Pharmaceutical composition for treating chronic pharyngitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1 buccal tablet

[0034] 【Prescription】Materials: 360g bamboo leek, 150g honeysuckle, 150g crocodile, 80g Radix Ophiopogon japonicus

[0035] Excipients: microcrystalline cellulose 300g, lactose 200g, stevia 10g

[0036]

[0037] [Preparation method] Take the prescription amount of honeysuckle, scrophulariaceae and Ophiopogon japonicus, soak in water for 30 minutes, decoct in water for 3 times, filter, combine the extracts, concentrate under reduced pressure to an extract with a relative ratio of 1.3 to 1.6, and dry at 60°C Add excipients and pass through a 80-mesh sieve; concentrate the prescribed amount of bamboo leek to about 100g under reduced pressure, add it to the sieved powder, mix well, make a soft material, and granulate with a 16-mesh mesh; granulate after drying at 60°C, add Magnesium stearate 5g, mixed evenly, pressed into 1000 tablets.

Embodiment 2

[0038] Example 2 Capsules

[0039] 【Prescription】Materials: 360g bamboo leek, 150g honeysuckle, 150g crocodile, 80g Radix Ophiopogon japonicus

[0040] Excipients: microcrystalline cellulose 280g lactose 160g

[0041]

[0042] [Preparation method] Take the prescription amount of honeysuckle, scrophulariaceae and Ophiopogon japonicus, soak in water for 30 minutes, decoct in water for 3 times, filter, combine the extracts, concentrate under reduced pressure to an extract with a relative ratio of 1.3 to 1.6, and dry at 60°C Add auxiliary materials, pass through a 80-mesh sieve, concentrate the prescribed amount of bamboo leek to about 100g under reduced pressure, add it to the sieved powder, mix well, make a soft material, and granulate with a 16-mesh mesh; after drying at 60°C, granulate, pack Capsules, made of 1000 capsules in total.

Embodiment 3

[0043] Embodiment 3 soft capsules

[0044] 【Prescription】Materials: 360g bamboo leek, 150g honeysuckle, 150g crocodile, 80g Radix Ophiopogon japonicus

[0045] Accessories: soybean oil 300g

[0046]

[0047] [Preparation method] Take the prescription amount of honeysuckle, scrophulariaceae and Ophiopogon japonicus, add water to soak for 30 minutes, decoct 3 times in water, filter, combine the extracts, add the prescription amount of bamboo leek, and concentrate under reduced pressure to a relative 1.3-1.6 The extract is dried at 60°C, crushed, passed through a 100-mesh sieve, mixed with soybean oil, and made into 1000 soft capsules.

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Abstract

The invention provides a pharmaceutical composition for treating chronic pharyngitis, which is a preparation prepared from raw materials in the following weight proportions: 30-60 parts of bamboo leek, 5-15 parts of honeysuckle, 9-15 parts of Scrophulariaceae, Ophiopogon japonicus 6~12 parts. The invention also provides the preparation method and application of the pharmaceutical composition. After the combination of various medicines is used in the invention, the synergistic effect is exerted, and the efficacy and activity of the medicine are significantly improved, which provides a new choice for clinical medicine.

Description

technical field [0001] The invention provides a pharmaceutical composition for treating chronic pharyngitis. Background technique [0002] Chronic pharyngitis is chronic inflammation of pharyngeal mucosa, submucosal and lymphoid tissue. Clinically, it is characterized by dry throat, itching, discomfort, foreign body sensation in the pharynx, or dry cough with little sputum. According to statistics, the incidence of chronic pharyngitis accounts for 10% to 12% of throat diseases, and it mostly occurs in adults. The incidence rate in cities is high, especially teachers and singers. Because of its repeated outbreaks, it brings a lot of discomfort to the patient. Clinically, the diagnosis can be confirmed based on the patient's subjective symptoms and physical examination signs. Generally divided into chronic simple pharyngitis, chronic hypertrophic pharyngitis, chronic atrophic pharyngitis. [0003] Western medicine generally believes that the causes of chronic pharyngitis a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P11/04A61P31/12A61P31/14
Inventor 苏柘僮熊永爱张帅杰
Owner XIAN BOAI PHARMA
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