Recombinant human-derived collagen product for skin barrier function or haemorrhoids and preparation method

A technology of human collagen and skin barrier, applied in bandages, absorbent pads, medical science, etc., can solve problems such as lack of internal hemorrhoid products, skin barrier function damage, etc.

Active Publication Date: 2015-06-03
SHANXI JINBO BIO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] In order to solve the problem of skin barrier function damage or lack of products in internal hemorrhoids, the present invention provides a series of recombinant human collagen products—medical skin collagen repair functional dressing, medical recombinant human collagen functional dressing (gel type), medical Recombinant human collagen functional dressing (spray type), collagen wound hemostatic material (hemorrhoid type), the invention also provides the preparation method of this series of products

Method used

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  • Recombinant human-derived collagen product for skin barrier function or haemorrhoids and preparation method
  • Recombinant human-derived collagen product for skin barrier function or haemorrhoids and preparation method
  • Recombinant human-derived collagen product for skin barrier function or haemorrhoids and preparation method

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0176] Medical skin collagen repair function dressing, ingredients include recombinant human collagen 0.05%; moisturizing emollient: sodium hyaluronate 0.8%, glycerin 0.3%, vaseline 0.2%, hydrogenated lecithin 0.15%, polydimethylsiloxane 0.8%, xanthan gum 0.5%, butanediol 0.2%, white mineral oil 0.8%, dipropylene glycol 0.3%, sunflower oil 3.5%, vitamin E 0.1%, vitamin C 0.5%; co-solvent: stearic acid 0.2%, 18 alcohol 0.3%; antibacterial preservatives: phenoxyethanol 0.8%, sodium methylparaben 0.05%, sodium propylparaben 1%; the balance water.

[0177] Taking the preparation of 1kg of dressing as an example, the concentration of recombinant human collagen is 0.05%, that is, each 1kg of dressing contains 0.5g of recombinant human collagen, and other ingredients are also calculated based on this. The specific preparation method is to dissolve the moisturizing emollient and co-solvent into 850g of pure water, stir evenly, then add recombinant human collagen filtered through a 0.2...

Embodiment 2

[0179] Medical skin collagen repair function dressing, ingredients include recombinant human collagen 0.1%; moisturizing emollient: sodium hyaluronate 0.1%, glycerin 3%, petrolatum 2%, hydrogenated lecithin 1.5%, polydimethylsiloxane 1.5%, xanthan gum 0.25%, butanediol 2%, white mineral oil 5%, dipropylene glycol 3%, sunflower oil 6%, vitamin E 0.75%, vitamin C 0.35%; solubilizer: stearic acid 2%, 18 alcohol 1.5%; antibacterial preservatives: phenoxyethanol 0.1%, sodium methylparaben 0.12%, sodium propylparaben 0.08%; the balance water.

[0180] Taking the preparation of 1kg of dressing as an example, the concentration of recombinant human collagen is 0.1%, that is, every 1kg of dressing contains 1g of recombinant human collagen, and other ingredients are also calculated based on this. The specific preparation method is to dissolve the moisturizing emollient and co-solvent into 880g of pure water, stir evenly, then add recombinant human collagen filtered through a 0.22μm membr...

Embodiment 3

[0182] Medical skin collagen repair function dressing, ingredients include recombinant human collagen 1%; moisturizing emollient: sodium hyaluronate 1%, glycerin 0.6%, petrolatum 4%, hydrogenated lecithin 1%, polydimethylsiloxane 4%, Xanthan Gum 1%, Butylene Glycol 4%, White Mineral Oil 10%, Dipropylene Glycol 6%, Sunflower Oil 1.5%, Vitamin E 1%, Vitamin C 1%; Solvent: Stearic Acid 1%, 18 Alcohol 6%; antibacterial preservatives: phenoxyethanol 1%, sodium methylparaben 2.2%, sodium propylparaben 2%; the rest water.

[0183] Taking the preparation of 1kg of dressing as an example, the concentration of recombinant human collagen is 1%, that is, every 1kg of dressing contains 10g of recombinant human collagen, and other ingredients are also calculated based on this. The specific preparation method is to dissolve the moisturizing emollient and co-solvent into 900g of pure water, stir evenly, then add recombinant human collagen filtered through a 0.22μm membrane, continue stirring ...

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Abstract

The invention relates to recombinant human-derived collagen series products for skin barrier function injuries or haemorrhoids, in particular to a medical recombinant human-derived collagen function dressing (spray type), medical skin collagen repair function dressing, medical recombinant human-derived collagen function dressing (gel type) and a collagen trauma hemostatic material (hemorrhoids type). The product provided by the invention has an obvious curative effect on skin barrier function injuries or haemorrhoids, and has popularization and application value.

Description

technical field [0001] The invention relates to a series of recombinant human collagen products for skin barrier function damage or hemorrhoids, in particular to a medical recombinant human collagen functional dressing (spray type), a medical skin collagen repair functional dressing, and a medical recombinant human collagen functional dressing (gel type), collagen wound hemostatic material (hemorrhoid type). Background technique [0002] 1. Skin barrier function [0003] The main basic structure of the skin barrier function is the stratum corneum, epidermal lipids and natural moisturizing factors. The skin barrier in a narrow sense mainly refers to the physical barrier, which is composed of stratum corneum, structural lipids and skin lipid film. The outermost line of defense. [0004] The skin barrier function prevents water loss and the invasion of the external environment. It is affected by many factors such as skin physiology, pathological changes and the external envi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/32A61L15/44A61L15/42A61L15/26
Inventor 杨霞
Owner SHANXI JINBO BIO PHARMA CO LTD
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