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Insulin pump with dynamic closed-loop control

An insulin pump, closed-loop control technology, applied in the field of medical devices, can solve problems such as testing, multi-source external interference, unknown, etc., and achieve good robustness.

Inactive Publication Date: 2015-06-03
SHANGHAI JIAO TONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the complexity of human body dynamics, the dynamics of "insulin-glucose concentration" is a typical unsteady process, which brings great difficulties to the design of control algorithms
[0010] 2) Nonlinear
[0012] 4) Multi-source external interference
This technology only describes the composition of each module of the blood glucose detection system, and does not give an explanation of the key algorithm of the control module, and the control of hyperglycemia or hypoglycemia in terms of real-time control is also unknown
At the same time, it is unable to address the problem of different insulin sensitivity of different patients, and fails to reflect this difference
The control algorithm in this technology only controls insulin for a single patient, and does not test the applicability of the algorithm in different environments

Method used

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  • Insulin pump with dynamic closed-loop control
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  • Insulin pump with dynamic closed-loop control

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] like figure 1 As shown, this embodiment includes: a drug delivery mechanism, a driving mechanism, a detection mechanism and a dynamic control module, wherein: the drug delivery mechanism is connected with the insulin pump and transmits insulin injection volume information, and the driving mechanism is connected with the injection device of the insulin pump and transmits control The injection amount information is connected with the detection mechanism and transmits the blood glucose information of the human body, and the dynamic control module is connected with the driving mechanism of the insulin pump and transmits the control information of the insulin-blood glucose value.

[0031] The insulin injection volume information refers to: the quantity value of insulin that needs to be injected at a certain moment.

[0032] The control injection volume information refers to a signal to promote insulin injection at a certain moment.

[0033] The blood sugar information of th...

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Abstract

The invention discloses an insulin pump with a dynamic closed-loop control in the field of medical equipment. The insulin pump comprises an administration mechanism, a driving mechanism, a detection mechanism and a dynamic control module, wherein the administration mechanism is connected with the insulin pump and transmits insulin injection amount information; the driving mechanism is connected with an injection unit of the insulin pump, and transmits and controls the injection amount information; the detection mechanism is connected with a glucometer and transmits human body blood glucose information; and the dynamic control module is connected with the driving mechanism of the insulin pump and transmits insulin-blood glucose level control information. The insulin pump with the dynamic closed-loop control can effectively reduce the unstabilizing factors due to a complex blood glucose system and has the relatively nice robustness after simulation testing. The insulin pump can control the blood glucose level of the diabetics and the injection amount of the insulin in time through model prediction and iterative control, so that the blood glucose level of the diabetics tends to be stable; and therefore, the effect of the insulin pump to control the injection automatically is achieved.

Description

technical field [0001] The invention relates to a technology in the field of medical equipment, in particular to a dynamic closed-loop controlled insulin pump. Background technique [0002] At present, there is no cure for diabetes in the medical field, and the treatment for diabetic patients in hospitals is limited to regular and quantitative injection of insulin before meals. Therefore, it is necessary and feasible to use medical equipment to replace or partially replace the blood sugar regulation function of pancreatic islets. choose. The current research on artificial islets focuses on completely closed-loop control of the insulin infusion rate, so as to fully replace the portable medical device that islets regulate blood sugar levels in real time. The control algorithm needs to have better robustness, so we propose such a control algorithm for insulin pump. [0003] The artificial islets are mainly composed of three parts, one is a blood glucose meter that can accurat...

Claims

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Application Information

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IPC IPC(8): A61M5/142A61M5/172
CPCA61M5/142A61M5/16804A61M5/1723A61M2230/005A61M2230/201
Inventor 易平高佳林宋怀东乔洁王文
Owner SHANGHAI JIAO TONG UNIV
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