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Medical biocolloid solution and preparation method thereof

A technology of biocolloid and bioglue, which is applied in medical science, surgery, etc., can solve the problems of unimproved water solubility, decreased antibacterial ability, and affecting the actual effect, etc.

Inactive Publication Date: 2015-07-01
HEBEI HUIBANG PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chitosan and carboxymethyl chitosan are the main components of chitosan wound washing products currently on the market, but the water solubility of the former has not been improved, and the latter has introduced negatively charged functional groups due to modification. While improving, the antibacterial ability decreased, which greatly affected the actual effect of product application

Method used

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  • Medical biocolloid solution and preparation method thereof
  • Medical biocolloid solution and preparation method thereof
  • Medical biocolloid solution and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Embodiment 1. The preparation of medical biological colloid of the present invention

[0019] prescription:

[0020]

[0021] The preparation method comprises the steps of:

[0022] a, take by weighing chitosan quaternary ammonium salt, fucoidan, sodium chloride of formula quantity, add water for injection to 100g, make chitosan quaternary ammonium salt containing 0.1%, 0.5% fucoidan, 0.1% chlorine Sodium chloride solution, for subsequent use;

[0023] b. Stir the solution obtained in step a evenly, place it for 2 hours, and filter it with a filter element to obtain a clear solution, which is set aside;

[0024] c. Fill the clarified solution obtained in step b into a glass bottle according to the 100ml specification and seal it to obtain the initial product, which is set aside;

[0025] d. Put the primary product obtained in step c into a sterilizer for high-temperature steam sterilization at 121° C., and then pack it after sterilization.

Embodiment 2

[0026] Embodiment 2. The preparation of medical biological colloid of the present invention

[0027] prescription:

[0028]

[0029] The preparation method comprises the steps of:

[0030] a, take by weighing chitosan quaternary ammonium salt, fucoidan, sodium chloride of formula quantity, add water for injection to 100g, make chitosan quaternary ammonium salt containing 3%, 4.5% fucoidan, 2% chlorine Sodium chloride solution, for subsequent use;

[0031] b. Stir the solution obtained in step a evenly, place it for 2 hours, and filter it with a filter element to obtain a clear solution, which is set aside;

[0032] c. Fill the clarified solution obtained in step b into a glass bottle according to the 100ml specification and seal it to obtain the initial product, which is set aside;

[0033] d. Put the primary product obtained in step c into a sterilizer for high-temperature steam sterilization at 121° C., and then pack it after sterilization.

Embodiment 3

[0034] Embodiment 3. the preparation of medical biological colloid of the present invention

[0035] prescription:

[0036]

[0037] The preparation method comprises the steps of:

[0038] a, take by weighing chitosan quaternary ammonium salt, fucoidan, sodium chloride of formula quantity, add water for injection to 100g, make chitosan quaternary ammonium salt containing 1.5%, 2.5% fucoidan, 0.9% chlorine Sodium chloride solution, for subsequent use;

[0039] b. Stir the solution obtained in step a evenly, place it for 2 hours, and filter it with a filter element to obtain a clear solution, which is set aside;

[0040] c. Fill the clarified solution obtained in step b into a glass bottle according to the 100ml specification and seal it to obtain the initial product, which is set aside;

[0041] d. Put the primary product obtained in step c into a sterilizer for high-temperature steam sterilization at 121° C., and then pack it after sterilization.

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Abstract

The invention relates to a medical biocolloid solution and a preparation method thereof and belongs to the technical field of medicinal instruments. The medical biocolloid solution is prepared from the ingredients in percentage by weight: 0.1-3% of chitosan quaternary ammonium salt, 0.5-4.5% of fucoidin, 0.1-2% of sodium chloride and the balance of water for injection. The medical biocolloid solution has very excellent technical effects on aspects, such as flushing effect, bacteriostasis effect, adverse reaction, biocompatibility, moisture retention property, bleeding arresting property and repairing action, and problems of the existing flushing products during use are solved, so that the medical biocolloid solution has very high advancement.

Description

technical field [0001] The invention relates to a medical dressing and a preparation method thereof, in particular to a medical biological colloid for wound washing and anti-adhesion operation and a preparation method thereof, belonging to the technical field of medical devices. Background technique [0002] At present, in the field of clinical medicine, traumatic wounds or surgical incisions need to be rinsed, and normal saline is more commonly used in clinical applications, but conventional normal saline irrigation can only wash away wounds or incisions, and cannot play a role in promoting healing and preventing adhesions . Therefore, many patients will experience postoperative incisions, wounds that are difficult to heal, and even postoperative adhesions, which cause great pain to the patients. [0003] Chitosan is non-toxic to the human body and has no immunogenicity. As an excellent biological material, it is widely used. However, due to its compact crystal structure, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/04A61L31/02A61L31/16A61L31/14
Inventor 许东迪张靖张妍刘聪敏王文通韩婷董新明
Owner HEBEI HUIBANG PHARMA TECH CO LTD
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