Tuna fishbone meal material, preparation method and application thereof

A technology of fish bone meal and tuna, which is applied in the field of medical and sanitary materials, can solve the problems of high cost of bone meal, weak bone capacity, and great difficulty, and achieve the effects of controllable product quality, promoting bone growth, and reducing heavy metal content

Active Publication Date: 2015-08-19
SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] At present, the natural bone materials used for bioactive filling materials are mainly leftover bones of cattle, sheep or pigs, and the aggregates need to be crushed, degreased, high-temperature cooking and other processing steps for many times, and the cost of preparing bone meal of cattle, sheep or pigs is high. It is difficult, and there are few active minerals in the bone, so the ability to promote bone formation is weak

Method used

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  • Tuna fishbone meal material, preparation method and application thereof
  • Tuna fishbone meal material, preparation method and application thereof
  • Tuna fishbone meal material, preparation method and application thereof

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Embodiment 1

[0043] The present embodiment provides a kind of tuna fish bone meal material, and it adopts following method to prepare:

[0044] (1) Select 2Kg of tuna fish bones that have been removed from most of the meat quality. After cleaning, use a bone and meat separator and a rolling mill to further remove meat and initially crush them. The preliminary broken tuna fish bones are expected to have a particle size of 5-20mm. ;Put the fish bones into the cooking pot for high-temperature and high-pressure cooking at a temperature of 100°C and a pressure of about 1.1 bar, and cook for about 2 hours to obtain the initial fish bones; the purpose of cooking is to initially remove a small amount of residual fish meat and lipids on the surface of the bone ; Then, filter and clean the fish bone primary material.

[0045] (2) Put the fishbone initial material after cleaning in the previous step into a molar concentration of 5% sodium bisulfite buffer and soak for about 3 hours to remove the heav...

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Abstract

The invention provides a tuna fishbone meal material, a preparation method and application thereof. The preparation method of the tuna fishbone meal material provided by the invention includes: conducting preliminary crushing on tuna fishbone to obtain a fishbone preliminary material, cooking the fishbone preliminary material at 90-100DEG C and under 1.0-1.1bar for 1-4h to obtain a fishbone initial material; soaking the fishbone initial material in a sodium hydrogen sulfite buffer solution with a mole concentration of 4-7% for 2-4h, then conducting calcinations at 800-1000DEG C for 4-10h to obtain a fishbone material, and then carrying out crushing and sieving treatment to obtain fishbone meal material with different particle size ranges. The invention additionally provides the tuna fishbone meal material prepared by the method. The invention also provides application of the tuna fishbone material as a medical orthopaedic filling material. The tuna fishbone material can be used as an individual bone filling material and dental filling material, and also can be compounded with other materials into widely applied biomedical materials.

Description

technical field [0001] The invention belongs to the field of medical hygiene materials, and in particular relates to a tuna fish bone meal material and a preparation method and application thereof. Background technique [0002] Studies have found that strontium has a dual mechanism to induce bone regeneration. First, the research on the mechanism of bone regeneration reveals that osteoblasts and osteoclasts are coupled together in bone remodeling. For the first time, it is clarified that osteoblasts and osteoclasts are not isolated during bone remodeling, but are coupled through TGF-beta1 signaling molecules. Secondly, in the study of the mechanism of strontium promoting osteogenesis, it was found that strontium may act through a completely different receptor from CaSR, that is, the Wnt pathway receptor LRP5 / LRP6. This breakthrough discovery brings new ideas to the treatment of osteoporosis. [0003] Aiming at the characteristics of strontium in the treatment of osteoporo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/36
Inventor 余遵雄崔旭高楠莎岳建辉李红龙窦庶华潘浩波
Owner SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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