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Traditional Chinese medicine composition for treating canine coronavirus infection and preparation method of traditional Chinese medicine composition

A technology of coronavirus and composition, which is applied in the field of traditional Chinese medicine composition and its preparation for the treatment of canine coronavirus infection, can solve the problems of easy recurrence, fast transmission speed, strong infectivity of canine coronavirus infection, etc., and achieve no drug resistance sex, no drug residue effect

Inactive Publication Date: 2015-09-16
TIANJIN DAYS NONGDA BIOTECH DEV LIMITED
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Canine coronavirus infection is highly contagious and spreads quickly, which is extremely harmful to puppies. If it is not controlled in time, it will cause a large number of deaths, and it is easy to relapse, which will bring great economic losses to the dog industry.
[0003] At present, there is no specific medicine for canine coronavirus infection, and symptomatic treatment is mainly used, such as antiemetic, antidiarrheal, rehydration, antibiotics to prevent secondary infection, or vaccination in advance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A traditional Chinese medicine granule for treating canine coronavirus infection, the parts by weight of each raw material are as follows: 30 parts of Evodia rutaecarpa, 10 parts of Codonopsis pilosula, 10 parts of ginger, 10 parts of Chinese yam, 10 parts of longan meat, 7 parts of honeysuckle, 8 parts of Brucea javanica, Pulsatilla 15 parts. The preparation method is as follows: (1) crush the traditional Chinese medicine to 60 mesh, weigh according to the formula amount, and three-dimensionally mix the traditional Chinese medicine powder; (2) put the traditional Chinese medicine powder into the extraction tank, add 10 times the amount of water and boil twice, each time Boil for 4 hours; (3) filter to remove medicinal residues, and combine the filtrate twice; (4) concentrate the filtrate under reduced pressure at 60°C to 10% of the original volume to obtain a concentrated extract; (5) weigh 30 parts of Yuanming powder, white granulated sugar 20 parts, 40 parts of starc...

Embodiment 2

[0029] A traditional Chinese medicine granule for treating canine coronavirus infection, the parts by weight of each raw material are as follows: 15 parts of Evodia rutaecarpa, 13 parts of Codonopsis pilosula, 15 parts of ginger, 15 parts of Chinese yam, 7 parts of longan meat, 13 parts of honeysuckle, 10 parts of Brucea javanica, Pulsatilla 12 parts. The preparation method is as follows: (1) crush the traditional Chinese medicine to 60 mesh, weigh according to the formula amount, and three-dimensionally mix the traditional Chinese medicine powder; (2) put the traditional Chinese medicine powder into the extraction tank, add 10 times the amount of water and boil twice, each time Boil for 4 hours; (3) filter to remove medicinal residues, and combine the filtrate twice; (4) concentrate the filtrate under reduced pressure at 60°C to 10% of the original volume to obtain a concentrated extract; (5) weigh 30 parts of Yuanming powder, white granulated sugar 20 parts, 40 parts of star...

Embodiment 3

[0031] A traditional Chinese medicine granule for treating canine coronavirus infection, the parts by weight of each raw material are as follows: 12 parts of Evodia rutaecarpa, 10 parts of Codonopsis pilosula, 10 parts of ginger, 12 parts of Chinese yam, 6 parts of longan meat, 15 parts of honeysuckle, 15 parts of Brucea javanica, Pulsatilla 20 parts. The preparation method is as follows: (1) crush the traditional Chinese medicine to 60 mesh, weigh according to the formula amount, and three-dimensionally mix the traditional Chinese medicine powder; (2) put the traditional Chinese medicine powder into the extraction tank, add 10 times the amount of water and boil twice, each time Boil for 4 hours; (3) filter to remove medicinal residues, and combine the filtrate twice; (4) concentrate the filtrate under reduced pressure at 60°C to 10% of the original volume to obtain a concentrated extract; (5) weigh 30 parts of Yuanming powder, white granulated sugar 20 parts, 40 parts of star...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating canine coronavirus infection and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials: fructus evodiae, codonopsis pilosula, fresh ginger, Chinese yam, longan aril, honeysuckle, brucea javanica and root of Chinese pulsatilla; the traditional Chinese medicine composition can be a granule. The preparation method comprises the following preparation steps: (1) crushing the traditional Chinese medicines into 40-100 meshes, weighing according to the formula ratio, and mixing in a three-dimensional manner to obtain traditional Chinese medicine powder; (2) feeding the traditional Chinese medicine powder into an extraction tank, adding 5-15fold water, and boiling twice and 2-12 hours each time; (3) filtering and removing herb residues, and merging filtrate of twice; (4) carrying out vacuum concentration on filtrate at 30-80 DEG C until the volume is 10%-30% of original volume to obtain a concentrated extract; (5) weighing 20-50 parts of anhydrous sodium sulphate, 10-50 parts of white granulated sugar and 20-60 parts of starch, and mixing the anhydrous sodium sulphate, the white granulated sugar and the starch; (6) evenly adding 10-20 parts of concentrated extract into the mixed powder by three times, adding while stirring for 10-30 minutes; and (7) granulating, and drying at 40-80 DEG C, so as to obtain the finished product. The traditional Chinese medicine composition provided by the invention has the efficacies of lowering the adverse flow of qi, preventing or arresting vomiting, supporting yang, checking diarrhea, strengthening the spleen, benefiting vital qi, soothing the nerves, clearing away heat and toxic materials, cooling blood and checking dysentery; and the recovery rate on the canine coronavirus infection can reach more than or equal to 95%.

Description

technical field [0001] The invention belongs to the field of Chinese veterinary medicine preparations, in particular to a Chinese medicine composition for treating canine coronavirus infection and a preparation method thereof. Background technique [0002] Canine coronavirus infection is a highly contagious disease mainly caused by gastroenteritis caused by canine coronavirus (CCV), and it is one of the main infectious diseases that endanger the dog industry at present. Canine coronavirus (CCV) can infect dogs of all breeds and ages (puppies suffer the most), causing gastroenteritis symptoms of varying severity, characterized by frequent vomiting, diarrhea, depression, anorexia and other symptoms. The disease can occur throughout the year, and is more frequent in winter. Sick dogs are the main source of infection. Dogs can be infected through the respiratory tract, digestive tract, feces and pollutants. The disease is highly contagious and spreads quickly, and can spread to...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P31/14
Inventor 曲荟芬何志霞贾庆红王郁刘强赵光伟刘毅斌
Owner TIANJIN DAYS NONGDA BIOTECH DEV LIMITED
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