Cetilistat tablet and preparation method
A celistat and tablet technology, applied in the field of pharmaceutical manufacturing, can solve problems such as unqualified dissolution rate, unqualified product quality stability inspection, tableting and splitting, etc.
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Embodiment 1
[0014] Selistat Tablets (Prescription Quantity 1000 Tablets)
[0015] Selistat Tablets (Prescription Quantity 1000 Tablets)
[0016]
[0017] Preparation process: Weigh the prescribed amount of celistat, mannitol, microcrystalline cellulose, and croscarmellose sodium, mix well, weigh the prescribed amount of high-substituted hydroxypropyl cellulose and add it to 80% ethanol Solution, stirring to dissolve completely, used as adhesive to connect to the fluidized bed. Add the mixture into the fluidized bed, turn on the fan to keep the mixture in suspension, add binder to make wet granules, and dry for 30 minutes. Take out the granules, add the prescribed amount of magnesium stearate, mix evenly, measure the content of the granules, and press into tablets according to the content of the granules. Finished product testing. The packaging is vested.
Embodiment 2
[0019] Selistat Tablets (Prescription Quantity 1000 Tablets)
[0020]
[0021] Preparation process: Weigh the prescribed amount of celistat, mannitol, microcrystalline cellulose, and croscarmellose sodium, mix well, weigh the prescribed amount of high-substituted hydroxypropyl cellulose and add it to 80% ethanol Solution, stirring to dissolve completely, used as adhesive to connect to the fluidized bed. Add the mixture into the fluidized bed, turn on the fan to keep the mixture in suspension, add binder to make wet granules, and dry for 30 minutes. Take out the granules, add the prescribed amount of magnesium stearate, mix evenly, measure the content of the granules, and press into tablets according to the content of the granules. Finished product testing. The packaging is vested.
Embodiment 3
[0023] Selistat Tablets (Prescription Quantity 1000 Tablets)
[0024]
[0025]
[0026] Preparation process: Weigh the prescribed amount of celistat, mannitol, microcrystalline cellulose, and croscarmellose sodium, mix well, weigh the prescribed amount of high-substituted hydroxypropyl cellulose and add it to 80% ethanol Solution, stirring to dissolve completely, used as adhesive to connect to the fluidized bed. Add the mixture into the fluidized bed, turn on the fan to keep the mixture in suspension, add binder to make wet granules, and dry for 30 minutes. Take out the granules, add the prescribed amount of magnesium stearate, mix evenly, measure the content of the granules, and press into tablets according to the content of the granules. Finished product testing. The packaging is vested.
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