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Drug for treating demyelinating polyneuropathy and preparation method of drug

A technology for polyneuropathy and demyelination, which can be applied to nervous system diseases, drug combinations, and pharmaceutical formulations, and can solve problems such as large side effects

Inactive Publication Date: 2015-11-04
哈尔滨泉兴科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, plasma exchange, intravenous immunoglobulin infusion and other methods are generally used to treat this disease, and western medicine is taken orally. During the treatment process of the above methods, patients suffer great pain, and the side effects are relatively large, and symptoms such as heart failure may even occur, which is dangerous. sex

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] A drug for demyelinating polyneuropathy and a preparation method thereof, which are prepared according to the following ratios in parts by weight: oryzanol 9-14 parts, Clematis 6-11 parts, Radix Paeoniae Alba 5-10 parts, Rhizoma Chuanxiong 6- 12 parts, 4-11 parts of loofah, 5-10 parts of curculigo, 6-9 parts of overlord flower, 5-8 parts of lost stick, 5-11 parts of golden button head, 6-12 parts of red madder, 5- 10 parts, 5-10 parts of Zhitian pepper, 6-11 parts of mountain orange, 5-12 parts of Cynomorium, 5-10 parts of wolfberry root, 6-11 parts of Eucommia, 5-10 parts of Magnolia officinalis, 4-8 parts of Qianjinzi 5-9 parts, solidago 5-9 parts. See Example 2 for the preparation method.

[0040] Typical cases:

[0041] Li, female, 36 years old, the patient said that her limbs were sore and weak, and her lower limbs gradually became paralyzed within two weeks. Yellow and greasy fur was diagnosed as acute inflammatory demyelinating polyneuropathy. After giving ...

Embodiment 2

[0043] Prepared according to the following weight ratios: 9 parts of oryzanol, 11 parts of Clematis, 8 parts of white peony, 12 parts of Chuanxiong, 4 parts of loofah, 7 parts of curculigo, 7 parts of Bawanghua, 8 parts of lost sticks, 5 parts of golden button head, 6 parts of red madder, 10 parts of phellodendron, 5 parts of Zhitian pepper, 9 parts of mountain orange, 9 parts of Cynomorium, 10 parts of wolfberry root, 11 parts of Eucommia, 5 parts of Magnolia officinalis, 6 parts of Qianjinzi, Solidago 7 servings.

[0044] Preparation method: prepared by the following steps,

[0045] (1) Remove impurities from the above-mentioned Chinese medicine raw materials, dry them in the sun, grind them into powder, and mix them evenly; (2) Put the above-mentioned Chinese medicine raw materials in a silver bucket and seal them, store them for 10 days, take them out and wrap them in kraft paper, and then Dry in the shade for 2 days; (3) Stir the oryzanol and the traditional Chinese m...

Embodiment 3

[0049] Prepared according to the following weight ratios: 11 parts of oryzanol, 8 parts of Clematis, 5 parts of white peony, 6 parts of Chuanxiong, 7 parts of loofah, 5 parts of curculigo, 9 parts of Bawanghua, 5 parts of lost sticks, 8 parts of golden button head, 10 parts of red madder, 7 parts of Phellodendron cortex, 10 parts of Zhitian pepper, 11 parts of mountain orange, 5 parts of Cynomorium, 8 parts of wolfberry root, 6 parts of Eucommia, 7 parts of Magnolia officinalis, 8 parts of Qianjinzi, Solidago 5 servings. The preparation method is the same as in Example 2.

[0050] Typical cases:

[0051] Pan, male, 34 years old, the condition is relatively slow. Within three weeks, the limbs gradually become weak, the waist and knees are sore and weak, and the muscles are thin, accompanied by dizziness and tinnitus, red tongue with less coating, and thready pulse. The diagnosis is acute inflammatory demyelinating disease. Polyneuropathy: Symptoms improved after one course ...

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PUM

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Abstract

A drug for treating demyelinating polyneuropathy is prepared from components in parts by weight as follows: 9-14 parts of oryzanol, 6-11 parts of clematis root, 5-10 parts of white peony root, 6-12 parts of Szechuan lovage rhizome, 4-11 parts of loofah sponge, 5-10 parts of common curculigo rhizome, 6-9 parts of pitaya flower, 5-8 parts of claoxylon indicumHassk, 5-11 parts of acmella oleracea, 6-12 parts of radix rubiae, 5-10 parts of phellodendron amurense, 5-10 parts of red cluster pepper, 6-11 parts of melodinus suaveolens, 5-12 parts of cynomorium songaricum, 5-10 parts of boxthorn root, 6-11 parts of eucommia bark, 5-10 parts of cortex magnoliae officinalis, 4-8 parts of caper euphorbia seeds and 5-9 parts of solidago. The drug has a very good treatment effect on acute inflammatory demyelinating polyneuropathy.

Description

technical field [0001] The invention relates to a medicine for demyelinating polyneuropathy. Background technique [0002] Acute inflammatory demyelinating polyneuropathy, the main lesion is extensive inflammatory demyelination of the nerve roots around the nerves, sometimes involving the meninges, spinal cord and brain, clinical features are rapidly developing symmetrical weakness of the extremities with tendon reflexes Mainly disappear. In severe cases, bulbar and respiratory muscle paralysis may be life-threatening. Primary disease mainly occurs in young adults and children, slightly more in men, and slightly more in winter and summer. About 2 / 3 of the patients had a history of upper respiratory tract or digestive tract infection several days to several weeks before the onset. At present, plasma exchange, intravenous immunoglobulin infusion and other methods are generally used to treat this disease, and western medicine is taken orally. During the treatment process of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P25/00A61P29/00A61K31/575
Inventor 闫丽华
Owner 哈尔滨泉兴科技有限公司