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Metronidazole and miconazole nitrate compound washing liquid and preparing method thereof

A metronidazole and miconazole nitrate compound formula and a technology for miconazole nitrate are applied in the field of metronidazole and miconazole nitrate compound lotion and preparation, and can solve the problems of slow effective effect and the like, achieve fast onset of effect, obvious synergistic effect, curative effect

Inactive Publication Date: 2015-11-25
QINGDAO HAIZHIYUAN INTELLIGENT TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, when metronidazole and miconazole nitrate are used alone to treat vaginitis, the symptoms of vaginitis caused by fungi are slow to take effect.

Method used

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  • Metronidazole and miconazole nitrate compound washing liquid and preparing method thereof
  • Metronidazole and miconazole nitrate compound washing liquid and preparing method thereof
  • Metronidazole and miconazole nitrate compound washing liquid and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A metronidazole nitrate miconazole compound lotion, the lotion components and parts by weight include: 5 parts of metronidazole, 8 parts of miconazole nitrate, 25 parts of Corydalis Corydalis, 45 parts of catechu, white fish tail 35 parts, Hydrangea 35 parts, Polygonum multiflorum 50 parts, Purslane 25 parts, Dog Antweed 50 parts, Zhi Licorice 35 parts, Angelica dahurica 15 parts, Cicada slough 8 parts.

[0038] A kind of preparation method of metronidazole nitrate miconazole compound lotion, comprises the following steps:

[0039] 1) preparing materials, preparing materials according to the components and parts by weight of a kind of metronidazole nitrate miconazole compound lotion;

[0040]2) Extraction of the active ingredients of the raw materials of traditional Chinese medicine, adding purified water into the extraction tank of Chinese medicines, the amount of purified water is 10 times the weight of the raw materials of traditional Chinese medicines, starting the ...

Embodiment 2

[0044] A metronidazole nitrate miconazole compound lotion, the lotion components and parts by weight include: 10 parts of metronidazole, 12 parts of miconazole nitrate, 30 parts of Corydalis Corydalis, 50 parts of catechu, white fish tail 40 parts, 40 parts of Hydrangea, 55 parts of Polygonum multiflorum, 30 parts of Purslane, 55 parts of Antweed, 40 parts of Zhi Licorice, 20 parts of Angelica dahurica, 12 parts of Cicada slough.

[0045] A kind of preparation method of metronidazole nitrate miconazole compound lotion, comprises the following steps:

[0046] 1) preparing materials, preparing materials according to the components and parts by weight of a kind of metronidazole nitrate miconazole compound lotion;

[0047] 2) Extraction of the active ingredients of the raw materials of traditional Chinese medicine, adding purified water into the extraction tank of Chinese medicines, the amount of purified water is 10 times the weight of the raw materials of traditional Chinese med...

Embodiment 3

[0051] A metronidazole nitrate miconazole compound lotion, the lotion components and parts by weight include: 7 parts of metronidazole, 11 parts of miconazole nitrate, 28 parts of Corydalis Corydalis, 47 parts of catechu, white fish tail 39 parts, 36 parts of Hydrangea, 53 parts of Polygonum multiflorum, 27 parts of Purslane, 51 parts of Antweed, 37 parts of Zhi Licorice, 18 parts of Angelica dahurica, 11 parts of Cicada slough.

[0052] A kind of preparation method of metronidazole nitrate miconazole compound lotion, comprises the following steps:

[0053] 1) preparing materials, preparing materials according to the components and parts by weight of a kind of metronidazole nitrate miconazole compound lotion;

[0054] 2) Extraction of the active ingredients of the raw materials of traditional Chinese medicine, adding purified water into the extraction tank of Chinese medicines, the amount of purified water is 10 times the weight of the raw materials of traditional Chinese medi...

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Abstract

The invention discloses metronidazole and miconazole nitrate compound washing liquid and a preparing method thereof. The washing liquid comprises, by weight, 5-10 parts of metronidazole, 8-12 parts of miconazole nitrate, 25-30 parts of rhizoma corydalis, 45-50 parts of cutch, 35-40 parts of Asian butteflybush roots and leaves, 35-40 parts of silence tenuis, 50-55 parts of polygonum multiflorum, 25-30 parts of purslane, 50-55 parts of green bristlegrass, 35-40 parts of radix glycyrrhizae preparata, 15-20 parts of radix angelicae, and 8-12 parts of periostracum cicadae. The preparing method comprises the steps of material preparation, crude traditional Chinese medicine effective constituent extraction and finished product preparation. The washing liquid is a Chinese and western medicine mixture, bacteriocidal / antimicrobial spectrum is improved, and the defect of western medicine that even though growth of most fungi is restrained, vaginitis caused by fungi can not be treated directly is overcome. The washing liquid is for local treatment of vaginitis through external use and directly acts on an affected part, the synergistic effect of multiple traditional Chinese medicines is remarkable, and the washing liquid becomes effective quickly and has a good treating effect.

Description

technical field [0001] The invention belongs to the field of topical external medicine, and specifically relates to a metronidazole nitrate miconazole compound lotion and a preparation method thereof. Background technique [0002] Vaginitis is the most common infectious disease in women. Its common symptoms are increased vaginal discharge, genital itching and burning pain, which may be accompanied by frequent urination, dysuria and dyspareunia. Gynecological examination showed increased vaginal discharge, vaginal mucosa hyperemia or scattered bleeding spots, a large amount of leucorrhea in the posterior fornix of the vagina, gray-yellow or yellow-green purulent discharge, sometimes foamy or white thick curd or bean dregs. Edema, scratches, and geographic erythema were seen on the vulva. [0003] Vaginal mucosal administration has a history of nearly a hundred years, and it has many advantages compared with traditional oral administration. It can be used not only locally, bu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/72A61P15/02A61P17/04A61P31/10A61P29/00A61K31/4164A61K31/4174A61K35/64
Inventor 袁国防周丽萍王小雅孙彦龙
Owner QINGDAO HAIZHIYUAN INTELLIGENT TECH