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Pain treatment plaster and preparation method thereof

A technology of plaster and horse chestnut, applied in the directions of medical preparations containing active ingredients, pharmaceutical formulas, non-central pain relievers, etc.

Inactive Publication Date: 2015-12-09
JINZHOU ZIJIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Currently there is no drug that can effectively relieve cancer pain and can be used for a long time

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment １

[0021] Embodiment 1: a kind of plaster for treating pain, the weight (parts) proportioning composition of its former medicine is:

[0022] Chansu 2.5, Shengchuanwu 75, Liangmianzhen 100, Aesculus 50, Shengguan Baifu 50, Hibiscus leaf 50, Sanleng 50, Curcuma 50, Safflower 50, Clove 25, Asarum 25, Cinnamon 25, Bali Ma 25, Piper longum 25, Nardin 50, Kaempferum 25, Frankincense 500, Myrrh 50, Menthol 100, Borneol 50, Camphor 50, Methyl salicylate 25, Benzyl alcohol 25, Diphenhydramine hydrochloride 50, Nitrogen Ketones 200.

Embodiment 2

[0023] Embodiment 2: a kind of plaster for treating pain, the weight (part) proportioning of its former drug is composed of:

[0024] Toad Su 10, Sheng Chuan Wu 150, Liangmianzhen 200, Aesculus 100, Shengguan Baifu 100, Hibiscus leaf 100, Sanleng 100, Curcuma 100, Safflower 100, Clove, 50, Asarum 50, Cinnamon 50, Balima 50, Piper longum 50, Nardin 100, Kaempferum 50, Frankincense 100, Myrrh 100, Menthol 200, Borneol 100, Camphor 100, Methyl salicylate 50, Benzyl alcohol 50, Diphenhydramine hydrochloride 50, Azone 200.

Embodiment 3

[0025] Embodiment 3: a kind of preparation method of the plaster for treating pain, its preparation steps are as follows:

[0026] (1) Grinding 2.5 parts by weight of Chansu into fine powder of 120 mesh;

[0027] (2) Extraction preparation: the parts by weight are: Shengchuanwu 75, Liangmianzhen 100, Aescin 1zhihua 50, Shengguan Baifu 50, Hibiscus leaf 50, Sanleng 50, Curcuma 50, Safflower 50, Clove 25, Asarum 25, cinnamon 25, Balima 25, longum longum 25, nard pine 50, kaempferum 25, frankincense 50, myrrh 50, pulverize into coarse powder, add 90% ethanol to heat and reflux three times, each time for 1 hour, filter; combine The filtrate was concentrated under reduced pressure to a relative density of 1.30 (measured at 50°C) to make an extract;

[0028] (3) Ointment preparation: parts by weight are menthol 100, borneol 50, camphor 50, methyl salicylate 25, benzyl alcohol 25, diphenhydramine hydrochloride 50, azone 200, pressure sensitive adhesive 1000, step (1 ) mixed with th...

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Abstract

The present invention relates to a pain treatment plaster and a preparation method thereof. The pain treatment plaster treat can treat cancer pain, improve quality of life of cancer patients, prolong the survival time, can also treat pains caused by external rheumatalgia, various injuries from falls, fractures, contusions and strains, soft tissue injuries and the like. The pain treatment plaster comprises the following original drugs by weight: 2.5-10 parts of venenum bufonis, 75-150 parts of radix aconiti kusenzoffii, 100-200 parts of radix zanthoxyli, 50-100 parts of paris polyphylla, 50-100 parts of raw Korean mondshood root, 50-100 parts of hibiscus leaves, 50-100 parts of rhizoma sparganii, 50-100 parts of curcuma zedoary, 50-100 parts of safflower, 25-50 parts of cloves, 25-50 parts of asarum, 25-50 parts of cinnamon, 25-50 parts of dysosma versipellis, 25-50 parts of fructus piperis longi, 50-100 parts of rhizoma nardostachyos, 25-50 parts of rhizoma kaempferiae, 50-100 parts of frankincense, 50-100 parts of myrrh, 100-200 parts of menthol, 50-100 parts of borneol, 50-100 parts of camphor, 25-50 parts of methyl salicylate, 25-50 parts of benzyl alcohol, 50 parts of diphenhydramine hydrochloride and 200 parts of azone.

Description

technical field [0001] The invention relates to a plaster and a preparation method thereof, in particular to a plaster for treating pain and a preparation method thereof. Background technique [0002] Pain is a common and main symptom of cancer patients, causing great physical and mental pain to patients and seriously affecting the quality of life of patients. In addition, pain caused by rheumatism, various bruises, soft tissue injuries, etc. is also a very common disease. The treatment of cancer pain usually adopts the three-stage drug analgesic method advocated by WHO, that is, the first stage of non-hormonal analgesics, the second stage of weak opioid analgesics such as codeine, and the third stage of strong opioid analgesics such as morphine , although it can achieve a certain curative effect, due to the particularity of long-term drug use in tumor patients, it will inevitably lead to patient intolerance, and drug overdose caused by drug tolerance and addiction will accu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/70A61P29/00A61K31/045A61K31/125A61K31/618A61K35/56
Inventor 宋丽华沈桂艳其他发明人请求不公开姓名
Owner JINZHOU ZIJIN PHARMA
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