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Medicinal composition for local burn nursing

A composition and drug technology, applied in the directions of drug combination, medical formula, plant raw materials, etc., can solve the problems of inconvenient administration, easy scabbing and debridement, toxic and side effects, etc. The effect of accelerating wound healing and treating burn infection

Inactive Publication Date: 2015-12-30
张玉玲
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

While antibiotics kill human pathogenic bacteria, they also kill other non-pathogenic bacteria (including some probiotics), thus destroying the balance of normal flora in the human body, causing flora disorder, and causing insensitive bacteria or fungi to multiply; Moreover, western medicine antibiotics are mostly a single action target, and bacteria are prone to drug resistance, causing antibiotics to fail; in addition, western medicine antibiotics also have many toxic and side effects, and can cause allergic reactions. Therefore, there are many disadvantages in the application of western medicine antibiotics
[0005] Most of the active parts of traditional Chinese medicine are mixtures, and the active components can play a synergistic effect. Even mutated pathogens can hardly find a way to survive in this complex antibacterial atmosphere; and the existing traditional Chinese medicines for the treatment of burn infections have no bactericidal effect. Good, the effect on drug-resistant bacteria is not obvious, because the wound cannot be moisturized, the wound surface is easy to scab and debridement is painful, and the administration is not convenient, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A pharmaceutical composition for local burn care, comprising the following components: 0.2% caffeic acid, 1% gentisic acid, 0.5% β-sitosterol, 0.04% triclosan, 0.3% palmitic acid, 5% β- Chitosan, 1% glutamic acid, 2% ethyl acetate, 0.04% methionine, 4% traditional Chinese medicine extract, 2% traditional Chinese medicine superfine powder, and the balance is auxiliary materials;

[0034] Among them, the traditional Chinese medicine extract is made by extracting the following two groups of traditional Chinese medicine raw materials:

[0035] Group A is calculated in parts by weight: 20 parts of hanging orchid, 5 parts of thorn catalpa, 10 parts of honeysuckle, 8 parts of bitter bark, 6 parts of licorice, 5 parts of Eupatorium, 9 parts of rice broken flower root, 30 parts of large Eucalyptus;

[0036] Group B is calculated in parts by weight: 16 parts of sage, 9 parts of wild watermelon seedlings, 7 parts of Baba flowers, 30 parts of Caitou kidney, 20 parts of mulberry le...

Embodiment 2

[0049] A pharmaceutical composition for local burn care, comprising the following components: 1.1% caffeic acid, 2% gentisic acid, 1.5% β-sitosterol, 0.05% triclosan, 0.65% palmitic acid, 6% β- Chitosan, 1.7% glutamic acid, 2.25% ethyl acetate, 0.07% methionine, 7% traditional Chinese medicine extract, 3.5% traditional Chinese medicine superfine powder, also includes 0.45% cat oil, and the balance is auxiliary materials;

[0050] Among them, the traditional Chinese medicine extract is made by extracting the following two groups of traditional Chinese medicine raw materials:

[0051] Group A is calculated in parts by weight: 25 parts of hanging orchid, 7.5 parts of thorny catalpa, 16 parts of honeysuckle, 14 parts of bitter bark, 10.5 parts of licorice, 10 parts of eupatorium, 12 parts of rice broken flower root, 37.5 parts of large Eucalyptus;

[0052] Group B is calculated in parts by weight: 23 parts of sage, 12 parts of wild watermelon seedlings, 8.5 parts of Baba flowers,...

Embodiment 3

[0065] A pharmaceutical composition for local burn care, comprising the following components: 2% caffeic acid, 3% gentisic acid, 2.5% β-sitosterol, 0.06% triclosan, 1.0% palmitic acid, 7% β- Chitosan, 2.4% glutamic acid, 2.5% ethyl acetate, 0.1% methionine, 10% traditional Chinese medicine extract, 5% traditional Chinese medicine superfine powder, also includes 0.6% cat oil, and the balance is auxiliary materials;

[0066] Among them, the traditional Chinese medicine extract is made by extracting the following two groups of traditional Chinese medicine raw materials:

[0067] Group A is calculated in parts by weight: 30 parts of hanging orchid, 10 parts of thorny catalpa, 22 parts of brevifolia, 20 parts of bitter bark, 15 parts of licorice, 15 parts of eupatorium, 15 parts of rice crushed root, 45 parts of large Eucalyptus;

[0068] Group B is calculated in parts by weight: 30 parts of sage, 15 parts of wild watermelon seedlings, 10 parts of Baba flowers, 40 parts of Caitou ...

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PUM

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Abstract

The invention discloses a medicinal composition for local burn nursing. The medicinal composition comprises caffeic acid, gentisic acid, beta-sitosterol, triclosan, palmitic acid, beta-chitosan, glutamic acid, ethyl acetate, methionine, Chinese medical extract, Chinese medicinal super micropowder and accessories, wherein raw materials of the Chinese medical extract comprise chlorophytum comosum, kalopanax, lonicera pampaninii, barks of Indian quassiawood, licorice, lycopus lucidus, eurya chinensis roots, eucalyptus robusta, pilea lomatogramma hand.-mazz, hibiscus trionum, abutilon indicum, championella sarcorrhiza, folium broussonetiae, bittersweet herb, dischidia minor, green lilies and radishes; raw materials of the Chinese medicinal super micropowder comprise psychotria serpens, whiteflower leadwood roots, rust powder made of iron and acetic acid, henon bamboo juvenile leaves, umbilicaria esculenta, pternopetalum botrychioides, herbs of shiny cinquefoil and passiflora henryi hemsl; the accessories comprise glycerin, sodium alginate, a preservative, an anti-oxidation reinforcing agent, a surfactant, a stabilizer, an isotonic regulator and injection water. According to the medicinal composition, multiple Chinese herbal medicaments are combined, so that the medicinal composition has the effects of clearing heat, removing toxicity, cooling blood, protecting the heart, removing dampness, nourishing yin, reinforcing qi, nourishing blood and resisting bacteria and viruses, and is free of irritation to skin, burn infection can be effectively treated, and wound healing can be accelerated.

Description

technical field [0001] The invention relates to the technical field of medical care, in particular to a pharmaceutical composition for local burn care. Background technique [0002] After burns, the skin is destroyed as a natural shield against microbial invasion, and the necrotic skin tissue is a good "culture medium" for the growth and reproduction of microorganisms. Therefore, burn wounds are highly susceptible to infection. In recent years, due to the improvement of the treatment level of burn shock, the mortality rate of shock has decreased significantly. However, burn infection has become the leading cause of death in severe burns. Prevention and treatment of burn infection is the key to burn treatment. Common bacteria causing infection are Staphylococcus aureus, Pseudomonas aeruginosa, Citrobacter freundii, nitrate-negative bacilli, and other enteronegative bacilli. Severe burns may also have bacterial infections, anaerobic bacteria and viral infections. [0003]...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P17/02A61K33/26A61K31/198A61K31/192A61K31/085
Inventor 张玉玲
Owner 张玉玲
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