Pharmaceutical composition for treating hyperostosis and preparation method of pharmaceutical composition

A bone hyperplasia and composition technology, applied in the field of medicine, can solve the problems of unsuitable temperature control, long course of treatment, slow effect, etc., and achieve the effect of supporting the body's righteousness, quick curative effect, and less toxic side effects

Inactive Publication Date: 2015-12-30
王玉龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, when using traditional Chinese medicine to treat hyperosteogeny, a single method such as external application or oral administration is often used for treatment. The course of treatment is long and the effect is slow, and the existing external application forms need to be heated in advance before hot compress, and the temperature is not suitable for control. Easy to cause burns and other problems

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A pharmaceutical composition for treating hyperosteogeny, comprising a combined oral dosage form and an externally applied dosage form;

[0029] The raw materials of oral dosage form are: Chuanshanlong 330g, Angelica dahurica 160g, Aracea 160g, Mianzi 330g, fried coix seed 160g, radish seed 160g, Tribulus terrestris 160g, Aconitum 180g, Aconitum 100g, brown sugar 30g;

[0030] Oral dosage form preparation method:

[0031] (1) Add 70vol% ethanol which accounts for 8 times the total weight of the 7 kinds of raw materials, and extract twice at 45°C, each After 90 minutes, the two extracts were combined and then concentrated to a paste (relative density: 1.1) to obtain a concentrated paste;

[0032] (2) Grind the fried barley and Angelica dahurica into powder to obtain a mixed powder, add the mixed powder and brown sugar to the above-mentioned concentrated paste, add honey, and make honeyed pills, each weighing 9g;

[0033] The dosage form for external application is comp...

Embodiment 2

[0038] A pharmaceutical composition for treating hyperosteogeny, comprising a combined oral dosage form and an externally applied dosage form;

[0039] The oral dosage form is made of the raw materials in the following weight proportions: 310g of Chuanshanlong, 150g of Angelica dahurica, 165g of Radix Araceae, 320g of Mianzi, 180g of fried barley, 150g of radish, 140g of Tribulus terrestris, 160g of Radix Aconiti, and 160g of Radix Black 90g, brown sugar 20g;

[0040] The preparation method of oral dosage form is with embodiment 1;

[0041] The dosage form for external application is composed of a medicine bag attached to the film and an acetic acid storage bag, and the medicine bag is made of the raw materials in the following weight ratio: 60g of safflower, 50g of Speranthema, 18g of centipede, and 80g of spinach , ephedra 70g, egg shell 70g;

[0042] The acetic acid reserve bag contains 210g of acetic acid;

[0043] The preparation method of the dosage form for external ...

Embodiment 3

[0045] A pharmaceutical composition for treating hyperosteogeny, comprising a combined oral dosage form and an externally applied dosage form;

[0046] The oral dosage form is made of the raw materials in the following weight proportions: 350g of Chuanshanlong, 140g of Angelica dahurica, 150g of Radix Araceae, 350g of Mianzi, 170g of fried barley, 155g of radish, 150g of Tribulus terrestris, 170g of Radix Aconiti, and 170g of Herb Black 80g, brown sugar 40g;

[0047] The preparation method of oral dosage form is with embodiment 1;

[0048] The dosage form for external application is composed of a medicine bag attached to the film and an acetic acid storage bag, and the medicine bag is made of the following raw materials in the weight ratio: 70g of safflower, 30g of Speranthema, 15g of centipede, and 100g of spinach , ephedra 90g, egg shell 60g.

[0049] The acetic acid reserve bag contains 180g of acetic acid;

[0050] The preparation method of the dosage form for external ...

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PUM

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Abstract

The invention belongs to the technical field of medicines and particularly relates to pharmaceutical composition for treating hyperostosis and a preparation method of the pharmaceutical composition. The pharmaceutical composition comprises an oral dosage form and an externally applied dosage form which are combined for use, wherein the oral dosage form comprises raw materials as follows: Japanese dioscorea roots, dahurian angelica roots, prepared jackinthepulpit tubers, sevenlobed yamn rhizomes, stir-fried coix seeds, radish seeds, tribulus fruits, prepared common monkshood mother roots, prepared kusnezoff monkshood roots and brown sugar; the externally applied dosage form comprises a medicine bag containing traditional Chinese medicine powder and attached to a film as well as an acetic acid storage bag, and the traditional Chinese medicine powder comprises raw materials as follows: safflower, trberculate speranskia herbs, centipedes, common cephalanoplos herbs, ephedra herbs and egg shells. Through combination of different delivery manners including an oral delivery manner and an external application delivery manner, the two manners are adopted simultaneously, the burden on intestines and stomachs of human bodies is reduced, toxic and side effects are small, the egg shells are added to the externally applied dosage form to have a the synergistic effect with acetic acid, drug infiltration can be promoted, the curative effect is quick, and both symptoms and root causes are treated.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for treating hyperosteogeny and a preparation method thereof. Background technique [0002] Osteoarthritis, also known as hypertrophic osteoarthropathy, is a chronic joint disease caused by joint degeneration and destruction of articular cartilage. It is a common clinical chronic low back and other strain diseases. The onset of hyperosteogeny is slow, without systemic symptoms, mostly middle-aged and elderly people over 50 years old. [0003] At the present stage, most of the drug effects are not long-lasting when Western medicine is used to treat hyperosteogeny, and the disease is easy to recur. It has been proved that Western medicine is not ideal for the treatment of hyperosteogeny. According to the argumentation of traditional Chinese medicine, bone hyperplasia is caused by kidney qi deficiency, qi and blood stasis, internal and exte...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61K36/286A61K36/47A61P19/08A61K31/7016A61K35/648A61K35/57
Inventor 王玉龙
Owner 王玉龙
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