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Method for improving bulk density of branched chain amino acid powder

An amino acid powder, branched-chain amino acid technology, applied in the direction of antidote, powder delivery, pharmaceutical formulations, etc., can solve the problems of high energy consumption, fine craftsmanship, etc., and achieve the effect of improving the taste of taking and increasing the bulk density.

Active Publication Date: 2016-02-03
AMINO LIFE WUXI BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These methods require elaborate processes or high energy consumption

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] The mass ratio of leucine, isoleucine and valine is 2:1:1, hydroxypropyl methylcellulose accounts for 0.4% of amino acid mass, trehalose accounts for 2% of amino acid mass, and hypromellose Base cellulose was mixed with water to make a solution with a mass fraction of 5%, then trehalose was added and stirred evenly, then branched-chain amino acids were added, stirred at 500rpm for 0.5h to make the amino acid materials and additives more evenly mixed, spray-dried and shaped, and passed 180 Mesh sieve to obtain branched-chain amino acid products.

Embodiment 2

[0014] The mass ratio of leucine, isoleucine and valine is 2:1:1, hydroxypropyl methylcellulose accounts for 0.5% of amino acid mass, trehalose accounts for 3% of amino acid mass, and hypromellose Base cellulose was mixed with water to form a solution with a mass fraction of 8%, then trehalose was added and stirred evenly, then branched-chain amino acids were added, stirred at 500rpm for 1 hour to make the amino acid materials and additives more evenly mixed, spray-dried and shaped, passed through 180 mesh Sieve to obtain branched-chain amino acid products.

Embodiment 3

[0016] The mass ratio of leucine, isoleucine and valine is 2:1:1, hydroxypropyl methylcellulose accounts for 0.45% of amino acid mass, trehalose accounts for 1% of amino acid mass, and hypromellose Base cellulose was mixed with water to form a solution with a mass fraction of 10%, then trehalose was added and stirred evenly, then branched-chain amino acids were added, and stirred at a speed of 500rpm for 0.5h to make the amino acid materials and additives more evenly mixed, spray-dried and shaped, and passed 180 Mesh sieve to obtain branched-chain amino acid products.

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Abstract

The invention discloses a method for improving the bulk density of branched chain amino acid powder and belongs to the field of amino acid preparations. The method comprises the steps that additives hydroxypropyl methyl cellulose (HPMC) and trehalose are added in the leucine, isoleucine and valine mixing process. The adding amount of the hydroxypropyl methyl cellulose is 0.4-0.5% by mass of amino acid, and the adding amount of the trehalose is 1-3% by mass of the amino acid. By adding an appropriate amount of the additives hydroxypropyl methyl cellulose and an appropriate amount of the trehalose, a branched chain amino acid product having stronger adhesive power is obtained, the bulk density of the branched chain amino acid product is improved from 0.25 to 0.3 g / ml and 0.65 to 0.8 g / ml.

Description

technical field [0001] The invention relates to a method for increasing the bulk density of branched-chain amino acid powder, belonging to the field of amino acid preparations. Background technique [0002] Amino Acid: A general term for a class of organic compounds containing amino and carboxyl groups. The basic unit of biological functional macromolecular protein is the basic substance that constitutes the protein required for animal nutrition, and is an important nutrient element for the human body to maintain normal physiological activities. For example: branched-chain amino acids, including L-leucine, L-isoleucine, and L-valine, are all essential amino acids for the human body, and their combination is referred to as BCAA (BranchChainAminoAcid). , Prolong life and other effects. It can help the body strongly resist muscle breakdown and nutrient loss, increase muscle stress resistance, promote protein synthesis and metabolism in the post-exercise recovery period, accel...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/38A61K47/26A61K31/198A61K9/14A61P3/02A61P39/00A61P5/00A61P37/04A61P21/00
Inventor 徐凤鸣
Owner AMINO LIFE WUXI BIOTECH
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