Traditional Chinese medicine composition for treating female postmenopausal osteoporosis and preparing method thereof

A technique for osteoporosis and composition, which is applied in the field of traditional Chinese medicine composition for treating postmenopausal osteoporosis in women and its preparation field, can solve the problems such as insignificant effect, and achieve the goal of not being easy to carry and take, being easy to popularize and apply, and preparing The effect of simple and easy process

Inactive Publication Date: 2016-02-17
GUANGDONG JUZHICHENG TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The drug for treating postmenopausal osteoporosis disclosed in Chinese invention patent application 201510238699.X is prepared from the following raw materials in the weight ratio: 15 parts of Cuscuta, 12 parts of Gorgon, 25 parts of Divine Comedy, 10 parts of Drynaria, 7 parts of Caulis Spatholobus, 8 parts of Red Vine, 10 parts of Passepartout, 12 parts of Elderberry, 6 parts of Qingpi, 5 parts of Curcuma, but the effect of the existing traditional Chinese medicine preparations for treating premenopausal osteoporosis is not significant

Method used

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  • Traditional Chinese medicine composition for treating female postmenopausal osteoporosis and preparing method thereof
  • Traditional Chinese medicine composition for treating female postmenopausal osteoporosis and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] The traditional Chinese medicine composition is prepared from the following Chinese medicinal materials in parts by weight: 10 parts of Moringa leaves, 6 parts of Dipsacus, 5 parts of Codonopsis pilosula, 5 parts of Polygonatum, 5 parts of Rehmannia glutinosa, 3 parts of Spatholobus, Clematis 3 parts of Angelica dahurica, 3 parts of Chinese yam, 3 parts of rhubarb and 1 part of licorice.

[0040] The preparation method is as follows:

[0041] S1: Take leaves of Moringa oleifera oleifera, wash them, dry them, crush them, pass through a 100-mesh sieve, add 8 times the amount of ethanol with a volume fraction of 65% of the total amount of medicinal materials, then add 1% of the total amount of medicinal materials Helicase, soak at 38°C Extract for 1 hour, then reflux extraction at 80°C for 3 hours, filter, and concentrate the filtrate under reduced pressure to an extract with a relative density of 1.10 at 60°C to obtain Extract A;

[0042]S2: Weigh Dipsacus, Codonopsis, P...

Embodiment 2

[0046] The Chinese medicine composition is prepared from the following Chinese medicinal materials in parts by weight: 15 parts of Moringa leaves, 10 parts of Dipsacus, 8 parts of Codonopsis, 8 parts of Rhizoma Polygonatum, 8 parts of Rehmannia glutinosa, 6 parts of Spatholobus, Clematis 6 parts, 6 parts of Angelica dahurica, 4 parts of Chinese yam, 4 parts of rhubarb and 5 parts of licorice.

[0047] The preparation method is as follows:

[0048] S1: Take leaves of Moringa oleifera oleifera, wash them, dry them, crush them, pass through a 120-mesh sieve, add 10 times the amount of ethanol with a volume fraction of 75% of the total amount of medicinal materials, then add 1.5% of the total amount of medicinal materials Helicase, soak at 40°C Extract for 2 hours, then reflux extraction at 85°C for 5 hours, filter, and concentrate the filtrate under reduced pressure to an extract with a relative density of 1.20 at 60°C to obtain Extract A;

[0049] S2: Weigh Dipsacus, Codonopsis...

Embodiment 3

[0053] The traditional Chinese medicine composition is prepared from the following Chinese medicinal materials in parts by weight: 25 parts of Moringa leaves, 15 parts of Dipsacus, 10 parts of Codonopsis pilosula, 10 parts of Rhizoma Polygonatum, 10 parts of Rehmannia glutinosa, 9 parts of Spatholobus, and Clematis clematis 9 parts, 9 parts of Angelica dahurica, 6 parts of Chinese yam, 6 parts of rhubarb and 10 parts of licorice.

[0054] The preparation method is as in Example 2.

[0055] Pharmacodynamic study of Chinese medicine composition of the present invention:

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Abstract

The invention belongs to the field of traditional Chinese medicine, and discloses a traditional Chinese medicine composition for treating female postmenopausal osteoporosis and a preparing method thereof. The traditional Chinese medicine composition is prepared from, by weight, 10-25 parts of moringa oleifera leaves, 6-15 parts of radix dipsaci, 5-10 parts of codonopsis pilosula, 5-10 parts of rhizoma polygonati, 5-10 parts of radix rehmanniae praeparata, 3-9 parts of caulis spatholobi, 3-9 parts of radix clematidis, 3-9 parts of radix angelicae, 3-6 parts of Chinese yam, 3-6 parts of rhubarb and 1-10 parts of liquorice. The traditional Chinese medicine composition is prepared from natural traditional Chinese medicine, side effect is small, the preparing process is simple, the functions of enriching blood and stopping pain, strengthening tendons and bones, and promoting blood circulation to remove meridian obstruction are realized, and female postmenopausal osteoporosis can be effectively treated.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating female postmenopausal osteoporosis and a preparation method thereof. Background technique [0002] Postmenopausal osteoporosis, belonging to primary osteoporosis type I, is a multifactorial disease, heredity, lifestyle, nutrition, etc. are all related to the onset, such as family history of osteoporosis, insufficient calcium intake, lack of Physical activity, heavy smoking and drinking, early menopause or premenopausal bilateral oophorectomy are more prone to the disease. The disease mainly occurs in postmenopausal women (50-70 years old), and is caused by estrogen deficiency leading to bone loss and changes in bone tissue structure, which increases bone fragility and makes it easy to fracture, as well as pain, bone deformation, and complications caused by fractures. , and even death, seriously affect the health...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P19/10A61P15/00
CPCA61K36/185A61K36/232A61K36/344A61K36/484A61K36/486A61K36/708A61K36/716A61K36/804A61K36/8945A61K36/8969A61K2236/19A61K2236/331A61K2236/333A61K2236/39A61K2236/51
Inventor 邓凤桂
Owner GUANGDONG JUZHICHENG TECH
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