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Pharmaceutical composition for treating diabetes, and preparation method and application thereof

A composition and diabetes technology, applied in the field of medical applications, can solve problems such as organ side effects and no substantial breakthrough in diabetes, and achieve the effect of reducing glycated serum protein, no toxic side effects, and lowering blood sugar

Inactive Publication Date: 2016-03-30
陈雪琴
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, dozens of Chinese and Western medicines are used in clinical treatment. However, due to the lack of substantial breakthroughs in the research on the pathology and etiology of diabetes, the treatment of diabetes is still in the research stage of controlling blood sugar, increasing urine sugar and preventing comprehensive complications.
In addition, patients who take western medicine for a long time will have side effects on the kidney, liver, heart, spleen, stomach and other organs.
The efficacy of various pure Chinese medicine preparations newly developed in China is also in the stage of controlling blood sugar and increasing urine sugar. There is no convincing scientific basis for any drug to repair human pancreatic tissue damage.

Method used

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  • Pharmaceutical composition for treating diabetes, and preparation method and application thereof
  • Pharmaceutical composition for treating diabetes, and preparation method and application thereof
  • Pharmaceutical composition for treating diabetes, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A pharmaceutical composition for treating diabetes, which is composed of the following raw materials in parts by weight: 20 parts of phoenix clothes, 20 parts of green calyx plum, 15 parts of scallion, 5 parts of anemarrhena, 5 parts of gallinaceous gold, 3 parts of dodder seed, and roasted licorice 3 parts, 1 part of epimedium.

[0021] The preparation method of the pharmaceutical composition for the treatment of diabetes, the specific steps are as follows:

[0022] (1) taking material: take each raw material according to parts by weight;

[0023] (2) Alcohol extraction: Take out half of each raw material, extract once at 70°C with 80% ethanol at a concentration of 5 times the weight of the material, and extract once for 20 minutes each time, combine the extracts obtained multiple times, and pass through 150 μm Sieve the permeate, concentrate until the water content is 50% to obtain the alcohol extract;

[0024] (3) Water extraction: crush the remaining raw materials...

Embodiment 2

[0028] A pharmaceutical composition for treating diabetes, which is composed of the following raw materials in parts by weight: 22 parts of phoenix clothes, 22 parts of green calyx plum, 16 parts of scallion, 7 parts of anemarrhena, 7 parts of gallinaceous gold, 3.5 parts of dodder, and roasted licorice 3.5 parts, 1.5 parts of epimedium.

[0029] The preparation method of the pharmaceutical composition for the treatment of diabetes, the specific steps are as follows:

[0030] (1) taking material: take each raw material according to parts by weight;

[0031] (2) Alcohol extraction: take out half of each raw material, extract 2 times at 75°C with 82% ethanol with a concentration of 5.5 times the weight of the material, and extract twice for 25 minutes. Sieve the permeate, concentrate until the water content is 45% to obtain the alcohol extract;

[0032] (3) Water extraction: crush the remaining raw materials to 0.6cm particles, then add water according to 12 times the weight o...

Embodiment 3

[0036] A pharmaceutical composition for treating diabetes, which is composed of the following raw materials in parts by weight: 25 parts of phoenix clothes, 25 parts of green calyx plum, 18 parts of scallion, 8 parts of anemarrhena, 8 parts of gallinaceous gold, 4 parts of dodder seed, and roasted licorice 4 parts, 2 parts of epimedium.

[0037] The preparation method of the pharmaceutical composition for the treatment of diabetes, the specific steps are as follows:

[0038] (1) taking material: take each raw material according to parts by weight;

[0039] (2) Alcohol extraction: take out half of each raw material, extract 3 times at 80°C with 85% ethanol with a concentration of 6.5 times the weight of the material, and extract 30 minutes each time, combine the extracts obtained multiple times, and pass through 200 μm Sieve the permeate, concentrate until the water content is 40% to obtain the alcohol extract;

[0040] (3) Water extraction: crush the remaining raw materials ...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating diabetes, and a preparation method and application thereof. The pharmaceutical composition for treating diabetes comprises the following raw materials by weight: inner shell membrane of fowl's egg, Prunus mume, Chinese garlic, rhizoma anemarrhenae, chicken's gizzard membrane, dodder seed, honey-fried licorice root and epimedium. The preparation method comprises the following concrete steps: weighing of the raw materials; alcohol extraction; water extraction; and preparation of the pharmaceutical composition. The invention provides application of the pharmaceutical composition in preparation of drugs used for treating diabetes. The pharmaceutical composition is capable of benefiting qi, nourishing yin, generating body fluid, clearing heat and reducing blood sugar; after administration of the pharmaceutical composition, blood sugar and urine sugar are effectively controlled, glycated serum protein obviously decreases, certain restoration effect is exerted on damage of alloxan to pancreas tissue, and no toxic and side effect is exerted; so the pharmaceutical composition provides a new option for a variety of symptoms caused by diabetes.

Description

technical field [0001] The invention relates to the technical field of medical application, in particular to a pharmaceutical composition for treating diabetes and its preparation method and application. Background technique [0002] Diabetes is one of the three most difficult diseases in the world. For decades, countries all over the world have carried out long-term and unremitting research and development. There have been two major breakthroughs in the history of diabetes treatment: the first was in the 1950s, when China first artificially synthesized insulin, which shocked the world; the second was the advent of biguanide and sulfonylurea oral hypoglycemic drugs, which made diabetic patients blood sugar can be temporarily controlled. At present, there are dozens of Chinese and Western medicines used in clinical treatment. However, since there is no substantial breakthrough in the research on the pathology and etiology of diabetes, the treatment of diabetes is still in th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61P3/10A61K35/57
CPCA61K35/57A61K36/296A61K36/39A61K36/484A61K36/736A61K36/8962A61K36/8964A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 陈雪琴
Owner 陈雪琴
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