36results about How to "Effective blood sugar control" patented technology

The present invention relates to a new-type hypoglycemic medicine composition. Said new-type hypoglycemic medicine composition contains biguanide hypoglycemic medicine or its medicinal salt with effective dose, thiazolidione hypoglycemic medicine or its medicinal salt with effective dose, vitamins B with effective dose and medicinal carrier or excipient. Said invention also provides the application of said medicine composition in preparation of medicine for preventing and / or curing diabetes and its complication.

The invention belongs to the technical field of biology, and more specifically relates to hpyerglycemic composition and hpyerglycemic composite probiotics food for special dietary uses. The hpyerglycemic composition is prepared by medicinal and edible traditional Chinese medicines having probiotic and hpyerglycemic efficacy through cooperation. The effective functional components in the medicinal and edible traditional Chinese medicines can regulate and control blood sugar as well as improves intestinal flora. The composition can better regulate and control blood sugar, can regulate balance of intestinal flora, and can increase the immunity. The hpyerglycemic composite probiotics food is prepared by the hpyerglycemic composition, the medicinal and edible traditional Chinese medicines and the probiotics enable synergistic effect and mutual promotion, so that body physique can be integrally regulated, and a normal health state is maintained. Based on the improvement of body nutrition status, the effects for regulating and controlling blood sugar, eliminating hunger, and regulating stomach can be achieved, under condition that the medicine usage amount is reduced for patients, blood sugar can be effectively controlled, and diabetes and complication can be delayed and prevented.

The invention belongs to the field of probiotic application and particularly relates to application of an Akkermansia muciniphila BAA-835 strain in preparation for treating or preventing diabetes mellitus. According to the application, controlled experiments on C57 / BL6 male SPF mouse littermates which are randomly divided into a control group and a strain gavage group are adopted, an Akkermansia muciniphila BAA-835 strain suspension gavage test is given to the strain gavage group once a day for 5 weeks. By means of the tests, the glucose tolerance area under the curve of the strain gavage group is reduced by 21.3 percent in comparison with that of the control group, which verifies that the Akkermansia muciniphila BAA-835 strain has an effect of improving glycometabolism and can be applied to the field of treatment or prevention of diabetes mellitus.

The invention relates to potato resistance increasing powder and potato steamed bun premixing powder with a function of lowering blood sugar and belongs to the technical field of food processing. The potato resistance increasing powder is obtained by crushing potatoes, standing and mixing washed sediment with water, then carrying out microwave, toughening and ageing treatment, and suction-filtering, drying and crushing aged potato pulp to obtain the potato resistance increasing powder. By using the microwave treatment, one part of amylopectin is degraded to form new short amylose so that the content of the amylose is increased. The toughening treatment moderately facilitates the rearrangement of amylose molecules so that the arrangement is relatively ordered; after the starch is aged, double-spiral structure are formed at the tail end regions of the amylose molecules; and the double-spiral structures are close to a spiral aggregating body under the effects of hydrogen bonds and Van der Waals force to form a stable crystal structure, so that the starch is not easy to degrade by enzymes and the content of resisting starch is improved. The potato resistance increasing powder is mixed with plain flour at a specific ratio to obtain the potato steamed bun premixing powder; and steam buns produced by the potato steamed bun premixing powder can be used for effectively controlling blood glucose of patients with diabetic nephropathy.

The invention relates to low-GI biscuits as well as a preparation method and application thereof, and belongs to the field of foods. The biscuits comprise the following raw materials of flour, maltitol, edible oil, a modifier, flavored raw materials, resistant dextrin containing soluble dietary fibers and being low in GI value, konjaku flour, celery powder containing insoluble dietary fibers and being low in GI value, tartarian buckwheat powder, soybean powder, green bean powder, wheat fiber powder and buckwheat powder or black rice powder. The preparation method of the low-GI biscuits comprises the following steps of mixing the green bean powder with the soybean powder to obtain a first mixture; enabling the maltitol and the modifier to dissolve to obtain a second mixture; and then mixingall of the raw materials, performing stirring, performing curing, performing calendering, performing shaping and performing baking. The method is simple and easy to operate, and large-scale production can be realized. The made biscuits are balanced in nutrients and high in content of dietary fibers, have low GI value, and are rich in fragrance and loose in mouth feel. The biscuits are suitable for being eaten by patients needing to control the blood sugar, the peak of the blood sugar of the patients after the meal can be effectively controlled, and besides, the biscuits are strong in satiation, and can achieve the effect of controlling the body weight.

The invention relates to a newly-developed medicine compound for diabetes which contains sulfonylureas drug for diabetes or a bioactive metabolite of the sulfonylureas drug for diabetes or pharmaceutical salt of the sulfonylureas drug for diabetes, and thiazolidinedione drug for diabetes or pharmaceutical salt and vitamin B of the thiazolidinedione drug for diabetes. The compound contains the sulfonylureas drug for diabetes of therapy dose or the bioactive metabolite of the sulfonylureas drug for diabetes or the pharmaceutical salt of the sulfonylureas drug for diabetes, the thiazolidinedione drug for diabetes of therapy dose or the pharmaceutical salt and therapy dose of vitamin B of the thiazolidinedione drug for diabetes or compound which is related to the thiazolidinedione drug for diabetes and has similar bioactivity and pharmaceutical carrier or excipient. The invention also relates to the purpose of the compound in preparation of drug for treating diabetes or preventing diabetes complication, belonging to the pharmaceutical field.

The invention belongs to the technical field of medicines, and particularly discloses an oral insulin nanometer granular preparation and a method for preparing the same. The oral insulin nanometer granular preparation is provided with core-shell structures. Cores of the oral insulin nanometer granular preparation are nanometer composite cores which comprise chitosan quaternary ammonium salt and insulin, and shells of the oral insulin nanometer granular preparation are hyaluronic acid or sulfhydrylation hyaluronic acid which is coated on the surfaces of the cores. The oral insulin nanometer granular preparation and the method have the advantages that nanometer grains are high in entrapment efficiency and / or medicine-loading rate and have small intestine mucus adhesion and penetration functions, accordingly, absorption of the insulin at small intestine positions can be improved, and the oral insulin nanometer granular preparation is high in oral bioavailability; blood glucose can be effectively controlled after the oral insulin nanometer granular preparation is orally taken, blood glucose change is stable as compared with subcutaneous injection, excellent blood glucose reducing effects can be realized by the oral insulin nanometer granular preparation, and the oral insulin nanometer granular preparation is high in bioavailability; the blood glucose can be effectively controlled,accordingly, unnecessary suffering of diabetes mellitus patients can be relieved to a great extent, and the oral insulin nanometer granular preparation is safe and convenient.

The invention discloses a Chinese medicinal preparation for treating diabetes, belonging to the field of medicines. The raw materials of active ingredients of the Chinese medicinal preparation consist of rhizome of Chinese asystasiella, yam, fruit of Thatch screwpine, litsea glutinosa, aralia chinensis, herb of rose glorybind, Chinese ladiestresses root, spirulina platensis, herb of Chinese mesona, leaf of cluster mallow, purple hypoestes herb, running mallow root, rhizome of whorledleaf solomonseal, stem and leaf of hedge glorybind, yew and herb of rough melic. The Chinese medicinal preparation has the effects of reinforcing qi, nourishing yin, promoting secretion of salvia or body fluid, clearing heat and lowering blood sugar, has an obvious treatment effect on phenomena of deficiency of vital qi such as lack of energy, tiredness, puffiness, weakness, or weight loss, thick tongue or teeth mark, is prepared from pure traditional Chinese medicines, has low toxic or side effect, can be used for treating both symptoms and root causes, can effectively control the blood sugar and the urine sugar to restore the functions such as strength and energy, has a certain recovery effect on pancreatic tissue damage, and has the characteristics of obvious curative effect, no relapse after cure, low cost, safety and stability.

The invention discloses a low-glycemic-value baked cake suitable for being eaten by people with diabetes mellitus and a production method of the baked cake. The baked cake is prepared from the following raw materials in parts by weight: 10-20 parts of a traditional Chinese medicine extract, 5-10 parts of albumen powder, 5-10 parts of oat bran, 0.5-1.5 parts of methyl alpha-D-glucopyranoside, 0.5-1.5 parts of di(2-aminoethyl)hydrogen phosphate (CAS:6094-81-1), 25-35 parts of inulin, 3-8 parts of egg white, 3-8 parts of a cake emulsifier, 1-3 parts of baking powder and 20-30 parts of water. Theprepared baked cake is low in glycemic value, is capable of assisting people with diabetes mellitus to effectively control blood glucose and has obvious effects on the prevention of hypoglycemia, cardio-cerebrovascular complications and diabetes mellitus and the delaying of hunger.

The invention discloses a composition for regulating blood sugar as well as a preparation method and application thereof. The composition comprises inulin, peanut peptide, galactooligosaccharide, isomaltooligosaccharide, beta-glucan and vitamin C; wherein the inulin is an inulin mixture with the polymerization degree of 24-60. The inulin is used as a main raw material, the polymerization degree of the inulin is optimized, and meanwhile, various prebiotics, dietary fibers and vitamin C are added, so that the components play a synergistic role, proliferation of intestinal probiotics can be promoted, and the intestinal environment can be improved; in addition, fermentation of beneficial bacteria can be promoted to generate short-chain fatty acid, the sensitivity of insulin of type II diabetes patients is improved, food intake is reduced, then blood sugar is effectively controlled, fasting blood glucose of the diabetes patients is remarkably reduced, and glycated serum protein and glucose tolerance levels are improved. The composition provided by the invention is comprehensive in nutrition and excellent in blood sugar reducing effect, and has important significance on treatment and prevention and treatment of diabetes.

The invention discloses a pharmaceutical composition for treating diabetes, and a preparation method and application thereof. The pharmaceutical composition for treating diabetes comprises the following raw materials by weight: inner shell membrane of fowl's egg, Prunus mume, Chinese garlic, rhizoma anemarrhenae, chicken's gizzard membrane, dodder seed, honey-fried licorice root and epimedium. The preparation method comprises the following concrete steps: weighing of the raw materials; alcohol extraction; water extraction; and preparation of the pharmaceutical composition. The invention provides application of the pharmaceutical composition in preparation of drugs used for treating diabetes. The pharmaceutical composition is capable of benefiting qi, nourishing yin, generating body fluid, clearing heat and reducing blood sugar; after administration of the pharmaceutical composition, blood sugar and urine sugar are effectively controlled, glycated serum protein obviously decreases, certain restoration effect is exerted on damage of alloxan to pancreas tissue, and no toxic and side effect is exerted; so the pharmaceutical composition provides a new option for a variety of symptoms caused by diabetes.

The invention provides a diabetes comprehensive nutrient formula food. According to the diabetes comprehensive nutrient formula food, selenium-enriched vegetable protein powder is taken as a nutritional raw material, a plurality of Chinese herbal medicines used for treating diabetes are added; and lily capable of nourishing heart and moistening lung, and clearing heart and calming the nerves, and polygonatum rhizome and haw which are capable of adjusting spleen and stomach functions are added; mannose oligomer is added to promote intestinal tract absorption, the diabetes comprehensive nutrient formula food possesses obvious effect on middle aged and old people with poor intestinal tract absorption functions. The diabetes comprehensive nutrient formula food can be prepared into a powder preparation for long term of eating, and can be absorbed easily.

The invention belongs to the technical field of food processing, concretely discloses a food composition, and also discloses a preparation method and a purpose of the food composition. The food composition is prepared by reasonably selecting and scientifically compounding the following components of brown rice, oats, purple potatoes, celeries, black fungus, soybean protein isolate, resistant dextrin, skimmed milk powder, crystalline fructose, konjak refined flour and white kidney bean extracts. The food composition can realize meal replacement satiety and achieves the effect of effectively controlling blood sugar. The invention also provides a preparation method of the food composition. A food composition product prepared by using the preparation method can achieve the effects of rapid dispersion after water addition and no agglomeration, is convenient to brew, and has good taste. The food composition provided by the invention can be used for meal replacement for diabetic people, weight reduction for normal people groups and the like.

The invention relates to special health steamed bread for chronic kidney diseases and belongs to the technical field of clinical nutritious foods. The special health steamed bread for the chronic kidney diseases comprises the following raw materials: 10 parts of wheat meal, 55-65 parts of starch, 4-8 parts of soluble dietary fibers, 10-15 parts of buckwheat meal and 10-15 parts of pearl barley powder, wherein the total amount of the buckwheat meal and the pearl barley powder is 20-25 parts. According to the special health steamed bread, the ratios of the wheat meal, the starch and the soluble dietary fibers are adjusted; and meanwhile, the buckwheat meal and the pearl barley powder, which are compounded according to the specific ratio, are added to prepare the special health steamed bread for the chronic kidney diseases, which has abundant nutritional ingredients and has the effects of improving the mouth feel, reducing the protein content and lowering the glucose improving index is prepared through adjusting the ratios of the wheat meal, the starch and the soluble dietary fibers and adding the buckwheat meal and the pearl barley powder which are compounded according to the specific ratio. The blood glucose and blood pressure can be effectively controlled after people eat the steamed bread for a long period, the development of CKD including diabetic nephropathy and hypertensive nephropathy, caused by a plurality of etiological factors, is delayed, and the health effect is good.

The diabetes treating medicine is one kind of Chinese medicine preparation and features that it is prepared with prepared rhizome of rehmannia, dogwood pulp, ophiopogon root, figwort root, morinda root and other eight kinds of Chinese medicinal materials in certain weight proportion. The present invention can control blood sugar and bi-directionally regulate blood sugar effectively, and has high total effective rate on diabetes, especially diabetes in the second stage.

The embodiment of the invention discloses a traditional Chinese medicine for treating diabetes, and relates to the technical field of medicine. The traditional Chinese medicine is prepared from, by weight, 4-12 parts of ginseng, 2-7 parts of cordyceps militaris, 9-17 parts of radix salviae miltiorrhizae, 5-13 parts of rhizoma atractylodis, 5-13 parts of radix curcumae, 5-13 parts of pericarpium citri reticulatae viride, 2-7 parts of Chinese magnoliavine fruit, 5-13 parts of radix scutellariae, 5-13 parts of cortex lycii radicis, 5-13 parts of rhizoma alismatis, 5-13 parts of fiveleaf gynostemma herb, 4-16 parts of flos lonicerae, 5-13 parts of herba salviae plebeiae and 9-16 parts of radix tinosporae. The traditional Chinese medicine for treating the diabetes has the advantages that the traditional Chinese medicine comprises the fourteen Chinese herbal medicine ingredients, acts on the internal organs, tonifies the lung and spleen, soothes the liver and nourishes the heart, promotes blood circulation to remove blood stasis, clears heat and removes toxicity, nurses the internal organs, restores the disordered viscera functions, enhances the degraded viscera function, cures diabetesfundamentally and is suitable for the treatment of the diabetes and complications thereof, taking is convenient and simple, and the effect is good.

The invention relates to a sugar-lowering drug composition and application thereof. The composition comprises 1) medicinal dosage of vildagliptin, 2) medicinal dosage of any one or combination of thiazolidinedione sugar-lowering drugs or medicinal salt thereof, sulfonylurea sugar-lowering drugs or medicinal salt thereof or biguanide sugar-lowering drugs or medicinal salt thereof and 3) B vitamins. The invention relates to application of the sugar-lowering drug composition to preparing the drugs for treating and / or controlling diabetes or diabetic complications. The composition can effectively overcome the defect that type 2 diabetes can not be controlled by singly taking the commonly used sugar-lowering drugs or vildagliptin in the prior art and simultaneously addition of the B vitamins is conductive to enhancing the treatment effect of the drug, effectively controlling the blood sugar, protecting the endothelial cell functions in a synergic manner, slowing rising of plasma homocysteine of the diabetes patients, especially the diabetes patients associated with chronic complications and reducing the diabetic complications.

The invention relates to a functional food composition for assisting in reducing blood sugar. The composition comprises the following components in parts by weight: 40-60 parts of a food mixture for reducing blood sugar, 10-20 parts of a food mixture rich in trace elements and 20-30 parts of a food mixture capable of improving the human immunity. The food mixture for reducing blood sugar includesChinese yams, bitter gourds, pumpkin, konjac, laver and onions. The food mixture rich in trace elements includes green soybeans, brown rice and pea seedlings. The food mixture capable of improving thehuman immunity includes hawthorn fruits, spirulina and lentinus edodes. The invention also provides a preparation method of the functional food composition for assisting in reducing blood sugar. Thefunctional food composition for assisting in reducing blood sugar can effectively control blood sugar, has no side effect, prevents and controls diabetic complications, and can improve organism immunity.

The invention discloses a healthcare biscuit exclusive for a diabetic and a preparation method thereof. Specifically, the healthcare biscuit exclusive for the diabetic not only can help the diabetic to effectively control blood glucose, but has obvious effects in preventing hypoglycemia, delaying hunger, enhancing satiety, preventing cardio-cerebrovascular complications and gout complications and preventing diabetes. The biscuit is characterized by being natural, nutritional, convenient, delicious, nontoxic and harmless, and belongs to the technical field of nutrition and healthcare food. The biscuit has the advantages that the healthcare mechanism of the product is clearer, 100% pure oat flour is used as a main material, the formula is precise, the defects of like products are overcome by means of auxiliary ingredients, and the biscuit has obvious advantages in functionality and safety.

The invention relates to the field of traditional Chinese herbal medicines and in particular to a traditional Chinese herbal medicine formula for treating diabetes and a preparation and application of the traditional Chinese herbal medicine formula. The traditional Chinese herbal medicine formula for treating diabetes is capable of stably reducing blood glucose, effectively controlling blood glucose, improving human body immunity and improving physiques of patients suffering from hyperglycemia and diabetes. In long-term taking of the preparation made of the traditional Chinese herbal medicine formula provided by the invention, damaged islet cells can be effectively repaired, insulin resistance can be alleviated, circulation of pancreas blood can be improved, pancreas blood undersupply can be alleviated, and transformation of pancreas islet functions and absorption and utilization of cells upon sugar can be accelerated.

The present invention provides an oral preparation comprising secondary wet granules prepared by coating the primary wet granules with a mixed aqueous solution of an α-glucosidase inhibitor and hydroxypropyl cellulose, wherein the primary wet granules are prepared by coating the primary wet granules with A mixed powder comprising metformin and hydroxypropyl cellulose is prepared by combining an aqueous solution of hydroxypropyl cellulose as a binding solution. In addition, the present invention provides a method for preparing an oral preparation, comprising the steps of: injecting mixed powder of metformin and hydroxypropyl cellulose into a fluidized bed granulator, and injecting an aqueous solution of hydroxypropyl cellulose spraying onto the mixed powder to produce primary wet granules; and spraying a mixed aqueous solution of an α-glucosidase inhibitor and hydroxypropyl cellulose onto the primary wet granules in a fluidized bed granulator to produce secondary wet granules.

The invention belongs to the technical field of medicine, and specifically discloses an oral preparation for lowering blood sugar and a preparation method thereof, which consists of the following raw materials in terms of weight fraction: 5-10 parts of gliclazide, 15-20 parts of metformin hydrochloride, aka 5-10 parts of wave sugar, 10-15 parts of carboxymethyl cellulose, 0.1-0.5 parts of magnesium stearate, 1-5 parts of polacrilin potassium resin (IRP88), 0.1-0.5 parts of aspartame and mannitol 5‑10 servings. The present invention combines several hypoglycemic drugs with different effects, which have synergistic effects, complement each other, improve curative effect, effectively control blood sugar, reduce complications, and effectively reduce body weight and blood fat while lowering blood sugar.

The invention provides brewing oat meal replacement porridge capable of regulating blood sugar balance and controlling body weight, and the brewing oat meal replacement porridge capable of regulating the blood sugar balance is prepared from the following components by weight: 50 parts of isomaltulose; 35 parts of oatmeal with hulls; 9 parts of oat powder; 3 parts of konjaku flour; 1 part of maltitol; 1 part of sorbitol; 0.5 part of a white kidney bean extract; 0.3 part of L-arabinose; 0.1 part of inulin; and 0.1 part of chitosan oligosaccharide. According to the functional brewing powder for regulating the blood sugar balance, the isomaltulose, the oatmeal, the oat flour and various saccharides are compounded, so that the functional brewing powder not only can help diabetic patients to effectively control blood sugar and help obese users to control body weight, but also has obvious effects in the aspects of preventing hypoglycemia, delaying hunger, preventing and treating cardiovascular and cerebrovascular complications and preventing diabetes.

The present invention provides an oral formulation which contains a secondary wet granule produced by coating a primary wet granule with a mixed aqueous solution of an alpha-glycosidase inhibitor and hydroxypropyl cellulose, wherein said primary wet granule is produced by combining a mixed powder comprising metformin and hydroxypropyl cellulose with an aqueous solution of hydroxypropyl cellulose serving as a binding solution. In addition, the present invention provides a method for preparing an oral formulation, comprising the steps of: injecting the mixed powder of metformin and hydroxypropyl cellulose into a fluidized bed granulator, and spraying the aqueous solution of hydroxypropyl cellulose onto the mixed powder to produce a primary wet granule; and spraying the mixed aqueous solution of alpha-glycosidase inhibitor and hydroxypropyl cellulose onto the primary wet granule in the fluidized bed granulator to produce a secondary wet granule.

The invention provides instant brewing powder for regulating blood sugar balance, the instant brewing powder for regulating the blood sugar balance is prepared from the following components in parts by weight: 45 parts of isomaltulose; 39 parts of coarse grain compound powder (oat, buckwheat, quinoa and the like); 5 parts of rice germs; 5 parts of wheat aleurone layer; 3 parts of konjaku flour; 1 part of maltitol; 1 part of sorbitol; 0.5 part of a white kidney bean extract; 0.3 part of L-arabinose; 0.1 part of inulin; and 0.1 part of chitosan oligosaccharide. According to the functional brewing powder for regulating the blood sugar balance, the isomaltulose, the coarse grain compound powder, the rice germs, the wheat aleurone layer and various saccharides are compounded, so that diabetes patients can be helped to effectively control blood sugar, moreover, the brewing powder has obvious effects in the aspects of preventing hypoglycemia, delaying hunger, preventing and treating cardiovascular and cerebrovascular complications, preventing diabetes and managing body weight.

The invention provides a functional beverage for regulating blood sugar balance, which is prepared from two main components: 1, a functional slow-release sugar formula component accounting for 10% by weight; and 2, the weight ratio of water and taste components of the beverage is 90%. The functional slow-release sugar is prepared from the following components: 60 parts of isomaltulose; 10 parts of rice germs; 10 parts of a wheat aleurone layer; 8 parts of konjaku flour; 5 parts of maltitol; 5 parts of sorbitol; 0.7 part of red date powder; 0.1 part of a white kidney bean extract; 0.1 part of L-arabinose; 0.05 part of inulin; and 0.05 part of chitosan oligosaccharide. According to the functional beverage for regulating blood sugar balance, the isomaltulose, the rice germs, the wheat aleurone layer and various saccharides are compounded, so that the functional beverage not only can help diabetic patients to effectively control blood sugar, but also has obvious effects in the aspects of preventing hypoglycemia, delaying hunger, preventing and treating cardiovascular and cerebrovascular complications, preventing diabetes mellitus and managing weight.

The invention provides a traditional Chinese medicine for treating diabetes and a preparation method. The traditional Chinese medicine is prepared from, by weight, 2-5 parts of milkvetch roots, 15-25 parts of prepared manyflower solomonseal rhizomes, 12-20 parts of stir-fried rhizoma atractylodis macrocephalae, 17-25 parts of common yam rhizomes, 24-40 parts of coix seeds, 16-25 parts of rhizoma polygonati odorati and 15-25 parts of semen lagenariae sicerariae. All the ingredients of the traditional Chinese medicine is soaked and decocted to obtain a traditional Chinese medicine preparation. The traditional Chinese medicine for treating the diabetes has the effects of benefiting qi, tonifying the spleen, reinforcing the kidney, securing essence, clearing heat and dispersing blood stasis, is used for treating the diabetes and has the advantages of effectively controlling blood glucose and being less in side effect and convenient to use, all the medicines supplement each other, and the effect is excellent.