Application of tannin micro-capsule in preparation of pig feed additive

A feed additive and tannin technology, which is applied in the application field of tannin microcapsules in the preparation of pig feed additives, can solve the problems of limited types of tannic acid products, no dosage form specifications, limited use methods, etc., and can change the palatability. Problems, few side effects, effect of promoting growth of pigs

Inactive Publication Date: 2016-04-06
GUANGZHOU INSIGHER BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It can be seen that in the field of animal medicine, the product types of tannic acid are limited and the use of specific products is limited, and it is inconvenient to use drugs due to lack of dosage form specifications

Method used

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  • Application of tannin micro-capsule in preparation of pig feed additive
  • Application of tannin micro-capsule in preparation of pig feed additive

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1 5

[0027] The preparation of embodiment 1 gallnut tannin gelatin microcapsule

[0028] At a temperature of 25°C, dissolve 10 g gallic tannin in a gelatin solution with a mass fraction of 4%, add 10% acetic acid solution to adjust the pH to 3.5-3.8, add 60% Na 2 SO 4 An appropriate amount of aqueous solution precipitates gelatin. Cool the reaction solution to 15°C, add an appropriate amount of 37% formaldehyde solution under stirring, then add 20% NaOH solution to adjust the pH to 7 to obtain Galla tannin gelatin solidified capsules, suction filter, and wash with water until formaldehyde-free to obtain Galla tannin gelatin Microcapsules. The content of Galla tannin in microcapsules is 27.4% by mass fraction.

Embodiment 2 5

[0029] The stability study of embodiment 2 Galla gall tannin gelatin microcapsules

[0030] Galla tannin gelatin microcapsules (prepared in Example 1) and galla tannin were placed in weighing bottles respectively, placed at 60°C for 10 days, and samples were taken on the 0th day, the 5th day and the 10th day, according to Purity analysis conditions were used to test the purity, and the results showed that the purity of Gallic tannin changed greatly on the 5th and 10th day at a temperature of 60°C, while the purity of Gallic tannin gelatin microcapsules remained stable (Table 1).

[0031] Table 1 Purity analysis of Galla tannin and its microcapsules after high temperature treatment

[0032] testing sample

Embodiment 3 5

[0033] Embodiment 3 Galla tannin gelatin microcapsules influence on pig feed palatability

[0034] 70 105-day-old healthy meat pigs with similar body weights were divided into 7 test groups as shown in Table 2, with 10 pigs in each group. Each group added Galla tannin in different forms and doses as shown in Table 2 to the basal feed, wherein the microcapsules represent Galla tannin gelatin microcapsules prepared in Example 1. All test pigs were fasted synchronously for 12 hours before the test. After 12 hours, the test pigs in each group were free to eat feed containing different doses of test samples, and observed for 30-60 minutes. When the test pigs no longer eat, the statistics of different test groups To evaluate the effect of adding different forms of gallic tannins to the feed on the feed intake of pigs. The simple feed without any form of Gallic tannin was used as the control group. The results showed that after adding different forms of gallic tannin in the feed, t...

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Abstract

The invention discloses an application of a tannin micro-capsule in preparation of a pig feed additive. According to the tannin micro-capsule and an oral preparation thereof, the problem about tannin palatability to pigs is remarkably solved, meanwhile, the oral preparation adopting gastrointestinal drug delivery is provided for the tannin as an antidiarrheal agent and a pig growth accelerant, and the tannin micro-capsule and the oral preparation thereof are the novel and safe pig feed additive with low side effects, are used for promoting pig growth and have broad application prospect in the pig breeding industry.

Description

Technical field: [0001] The invention belongs to the field of feed additives, in particular to the application of tannin microcapsules in the preparation of pig feed additives. Background technique: [0002] Microcapsules or microcapsules are microcapsules with a diameter of 1-5000 microns formed by using natural or synthetic polymer materials as the capsule wall shell to wrap solid or liquid drugs. The process of making microcapsules is called microencapsulation. Drug microencapsulation can improve the stability of the drug, mask the bad smell and taste of the drug, prevent the inactivation of the drug in the gastrointestinal tract, reduce the irritation of the drug to the gastrointestinal tract, slow or control the release of the drug, and make the liquid drug solid It has the characteristics of simplification, reducing drug compatibility changes and concentrating drugs in the target area. Microencapsulated drugs can also be further made into microencapsulated preparatio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K50/30A23K20/00
Inventor 彭险峰覃宗华
Owner GUANGZHOU INSIGHER BIOTECHNOLOGY CO LTD
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