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Traditional Chinese medicine composition for treating pollen allergy

A technology for pollen allergy and composition, applied in the field of medicine, can solve problems such as insignificant treatment effect, achieve the effects of less toxic and side effects, simple raw materials, and improved treatment effect

Inactive Publication Date: 2016-05-18
INST OF BASIC RES & CLINICAL MEDICINE CHINA ACAD OF CHINESE MEDICAL SCI +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are not many compositions for treating pollen allergy, and the therapeutic effect is not significant

Method used

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  • Traditional Chinese medicine composition for treating pollen allergy
  • Traditional Chinese medicine composition for treating pollen allergy
  • Traditional Chinese medicine composition for treating pollen allergy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A traditional Chinese medicine composition for treating pollen allergy, comprising the following raw materials in parts by mass: 4 parts of ephedra extract, 11 parts of trichosanthemi extract, mixed uniformly.

[0022] The extraction method of described ephedra extract is:

[0023] (1) Crush ephedra, pass through a 10-mesh sieve, add 3 times the weight of 50% ethanol, heat and reflux at 70°C for 2 extractions, each time for 40 minutes, combine the extracts, and filter to obtain the filtrate;

[0024] (2) Use 0.5mol / L NaOH solution to adjust the pH of the filtrate to 9-10, then pass the filtrate through the ion exchange resin column at a flow rate of 1mL / min, and then use 2BV of 0.5-1.5mol / L ammonia water, 2BV 1.0mol / L ammonia water and 80% ethanol mixture, 2BV 2.0mol / L ammonia water and 70% ethanol mixture were eluted sequentially, the elution flow rate was 1mL / min, and the eluents were combined;

[0025] (3) Concentrate the eluent under reduced pressure to obtain an e...

Embodiment 2

[0032] A traditional Chinese medicine composition for treating pollen allergy, comprising the following raw materials in parts by mass: 6 parts of ephedra extract, 13 parts of trichosanthes extract, mixed uniformly.

[0033] The extraction method of described ephedra extract is:

[0034] (1) Crush ephedra, pass through a 10-mesh sieve, add 4 times the weight of 50% ethanol, heat and reflux at 75°C for 2 extractions, each time for 50 minutes, combine the extracts, and filter to obtain the filtrate;

[0035] (2) Use 0.5mol / L NaOH solution to adjust the pH of the filtrate to 9-10, then pass the filtrate through the ion exchange resin column at a flow rate of 1.2mL / min, and then use 3BV of 1.0mol / L ammonia water and 3BV of 1.5mol / L ammonia water and 80% ethanol mixture, 3BV of 2.5mol / L ammonia water and 70% ethanol mixture were eluted sequentially, the elution flow rate was 1.2mL / min, and the eluents were combined;

[0036] (3) Concentrate the eluent under reduced pressure to ob...

Embodiment 3

[0043] A traditional Chinese medicine composition for treating pollen allergy, comprising the following raw materials in parts by mass: 8 parts of ephedra extract, 15 parts of trichosanthemi extract, mixed uniformly.

[0044] The extraction method of described ephedra extract is:

[0045] (1) Crush ephedra, pass through a 10-mesh sieve, add 5 times the weight of 50% ethanol, heat and reflux at 80°C for 2 extractions, each time for 60 minutes, combine the extracts, and filter to obtain the filtrate;

[0046] (2) Use 0.5mol / L NaOH solution to adjust the pH of the filtrate to 9-10, then pass the filtrate through the ion exchange resin column at a flow rate of 1.5mL / min, and then use 4BV of 1.5mol / L ammonia water and 4BV of 2.0mol / L ammonia water and 80% ethanol mixture, 4BV of 3.0mol / L ammonia water and 70% ethanol mixture were eluted sequentially, the elution flow rate was 1.5mL / min, and the eluents were combined;

[0047] (3) Concentrate the eluate under reduced pressure to o...

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Abstract

The invention discloses traditional Chinese medicine composition for treating pollen allergy. The traditional Chinese medicine composition is prepared from extracts of ephedra herbs and mongolian snakegourd roots and can be prepared in any oral dosage form in pharmacy, such as tablets, capsules, granules, pills and syrup. Raw materials are simple, by comparison with other composition for treating pollen allergy, the cost is reduced, a specific traditional Chinese medicine extraction method is adopted, the extraction rate of effective ingredients of traditional Chinese medicines is increased, the treatment effect is improved, and the traditional Chinese medicine composition has few toxic and side effects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating pollen allergy, which belongs to the field of medicine. Background technique [0002] In nature, pollen is a major allergen. Whenever the spring is warm and the flowers are blooming, the most likely to cause pollen allergies are seed trees, such as wolfberry, castor, Kochia, and sycamore. These plants have a large amount of pollen, small size, high content in the air, and are easier to spread on windy days, so more people suffer from pollen allergies during outings in spring. [0003] After the oily and polysaccharide substances contained in pollen are inhaled, they will be digested by nasal secretions, and then more than ten kinds of antibodies will be released. If this antibody meets the invading pollen and accumulates in large quantities, it will cause skin allergies. [0004] At present, there are not many compositions for treating pollen allergy, and the therapeuti...

Claims

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Application Information

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IPC IPC(8): A61K36/428A61P37/08A61K36/17
CPCA61K36/17A61K9/0095A61K9/1652A61K9/2059A61K36/428A61K2236/333A61K2236/39A61K2236/55A61K2300/00
Inventor 吕爱平张戈吕诚赵宁王茂林白箐安党蕾何冰
Owner INST OF BASIC RES & CLINICAL MEDICINE CHINA ACAD OF CHINESE MEDICAL SCI
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