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Traditional Chinese medicine for treating allergic cutaneous vasculitis and preparation method

A technology for skin vasculitis and allergies, applied in skin diseases, pharmaceutical formulations, cardiovascular system diseases, etc., can solve the problems of obvious side effects, high recurrence rate, unsuitable for long-term application, etc., achieve no toxic side effects, exact curative effect, Effect without adverse reaction

Inactive Publication Date: 2016-06-15
高伟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine hormone therapy has obvious side effects, high recurrence rate, and difficult to control dosage, so it is not suitable for long-term application

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0037] The present invention also provides a preparation method of the above-mentioned Chinese medicine, the dosage form of the Chinese medicine is a capsule, and the preparation method includes the following steps:

[0038] In the first step, the raw materials of the traditional Chinese medicine composition are mixed in proportions, and ethanol with an alcohol concentration of 80 to 90% is added 3 to 5 times the mass of the mixture. The mixture is heated and refluxed for 40 to 60 minutes, extracted and filtered to obtain the first Extraction solution; the drug residue obtained by filtration is added with ethanol with an alcohol concentration of 80-90% which is 2 to 3 times the mass of the drug residue, heated under reflux for 30-50 minutes, extracted and filtered to obtain the second extract; the first extraction The liquid and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0039] In the second...

Embodiment 1

[0045] Example 1: Capsules

[0046] Take the golden thread grass 110g, the stone cicada grass 60g, the Hanxin grass 80g, the sorrel 320g, the bitter 490g, the orientia root 260g, the dog bone chai 70g, the three leaves 460g, the tree head cabbage root 140g, the butterfly vine 220g, the white bamboo shoots and leaves 130g, willow root 240g, large leaf horsetail 580g and snake root 340g;

[0047] Prepare according to the following steps:

[0048] The first step is to mix the raw materials of the traditional Chinese medicine composition in proportion, add ethanol with an alcohol concentration of 80% that is 4 times the mass of the mixture, heat and reflux for 60 minutes, extract, and filter to obtain the first extract; The medicine residue is added with ethanol with an alcohol concentration of 80% which is 3 times the mass of the medicine residue, heated to reflux for 30 minutes, extracted and filtered to obtain a second extract; the first extract and the second extract are combined an...

Embodiment 2

[0051] Example 2 Granules

[0052] Take the golden thread grass 130g, the stone cicada 90g, the Hanxin grass 70g, the sorrel 350g, the bitter 460g, the water chestnut root 280g, the dog bone wood 50g, the three leaves 480g, the tree head root 110g, the butterfly vine 250g, the white bamboo shoots and leaves 120g, willow root 220g, large leaf horsetail 560g and snake root 320g;

[0053] Prepare according to the following steps:

[0054] The first step: Mix the raw materials according to the ratio, add 90% ethanol with 3 times the alcohol concentration of the mixture, heat to boiling and reflux for 2 hours, filter, and use percolation at a rate of 2ml per minute. Slowly permeate, collect the percolate, and then concentrate it to a paste with a relative density of 1.05 at 75°C under a vacuum of 0.01Mpa, and spray dry. The inlet air temperature of the spray dryer is 180°C and the outlet air temperature is 80°C. Then pulverize into powder to make dry paste powder;

[0055] The second ste...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for treating allergic cutaneous vasculitis and a preparation method. The traditional Chinese medicine comprises the following raw medicine materials: polygonum filiforme, dindygulen peperomia herb, Indian skullcap herb with root, endive, physalis angulata, polygonum orientale root, diplospora dubia, threeleaf loosestrife herb, unilocular crateva root, passiflora papilio, acanthopanax trifoliatus branches and leaves, bast willow root, faber meadowrue root and rhizome and ophiorrhiza japonica. The traditional Chinese medicine provided by the invention has the beneficial effects of exact curative effect, no toxic or side effect and no adverse reaction when used for treating allergic cutaneous vasculitis by matching with a western medical conventional method.

Description

Technical field [0001] The invention relates to medical preparations containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for treating allergic skin vasculitis and a preparation method. Background technique [0002] Allergic cutaneous vasculitis (allergiccutaneous vasculitis) is also known as allergic vasculitis (allergic vasculitis), systemic allergic vasculitis (systemicallergic vasculitis), nodular cutaneous allergic rash (nodulardermalallergidi). It is a necrotizing inflammation of dermal capillaries and tiny blood vessels. It is more common in young people. Acute bacterial or viral infections often occur 1 to 2 weeks before the onset of this disease. Most patients only have skin involvement, and a few can involve internal organs. [0003] The initial lesions range from miliary to mung bean scarlet maculopapular rash and purpura, which gradually increase and can become blisters or blood blisters, or dark red nodules. ...

Claims

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Application Information

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IPC IPC(8): A61K36/81A61P17/00A61P9/14
CPCA61K36/81A61K9/1652A61K9/4866A61K36/185A61K36/254A61K36/28A61K36/52A61K36/539A61K36/67A61K36/70A61K36/704A61K36/71A61K36/74A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 高伟赵莹莹
Owner 高伟
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