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Compound preparation for treating rheumatic arthritis

A technology for rheumatoid arthritis and compound preparations, which is applied in the direction of anti-inflammatory agents, non-central analgesics, and medical preparations containing active ingredients. It is convenient to take and carry, and the effect of eliminating pain

Inactive Publication Date: 2016-08-10
JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the onset of action is slow and the treatment period is long

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A compound preparation for treating rheumatoid arthritis, comprising the following components in the following mass percentages: 2% of prednisone acetate, 75% of cinnamaldehyde, and the balance is pharmaceutical filling materials.

[0022] Cinnamaldehyde and prednisone acetate are taken in mass percentages, cinnamaldehyde is clathrated with β-cyclodextrin, prednisone acetate is added with medicinal filling auxiliary materials, stirred and mixed, granulated, and granulated. The sized prednisone acetate granules are mixed with β-cyclodextrin-included cinnamaldehyde granules, and can be compressed into tablets and coated with film coating or sugar coating.

[0023] The tablet can be used for treating rheumatoid arthritis, rapidly relieves symptoms of rheumatoid arthritis, and achieves the effects of anti-inflammation and pain relief, expelling wind and dampness, warming meridians and expelling cold.

Embodiment 2

[0025] A compound preparation for treating rheumatoid arthritis, comprising the following components in the following mass percentages: 8% of prednisone acetate, 60% of cinnamaldehyde, and the balance is pharmaceutical filling materials.

[0026] Cinnamaldehyde and prednisone acetate are taken in mass percentage, and cinnamaldehyde is clathrated with β-cyclodextrin. Prednisone acetate is added to pharmaceutical filling materials, stirred and mixed, granulated, and granulated. The sized prednisone acetate granules are mixed with β-cyclodextrin-included cinnamaldehyde granules, and directly filled into capsules.

[0027] The capsule can be used for treating rheumatoid arthritis, rapidly relieves symptoms of rheumatoid arthritis, and achieves the effects of anti-inflammation and pain relief, expelling wind and dampness, warming meridians and expelling cold.

Embodiment 3

[0029] A compound preparation for treating rheumatoid arthritis, comprising the following components in the following mass percentages: 10% of prednisone acetate, 15% of cinnamaldehyde, and the balance is pharmaceutical filling materials.

[0030] Take polyvinyl alcohol-6000, which is 3 times the total weight of prednisone acetate and cinnamaldehyde in mass percentage, and heat it to 70°C. After melting, add prednisone acetate and cinnamaldehyde, stir evenly, move to the dropping pill machine, and keep melting The temperature of the solution is 50°C, and it is dropped into glycerin at 10°C from top to bottom at a moderate dropping speed to make drop pills, which are then coated.

[0031]The dropping pill can be used for treating rheumatoid arthritis, rapidly relieves symptoms of rheumatoid arthritis, and achieves the effects of anti-inflammation and pain relief, expelling wind and dampness, warming meridian and expelling cold.

[0032] The invention is a compound preparation p...

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PUM

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Abstract

The invention discloses a compound preparation for treating rheumatic arthritis. The compound preparation consists of the following raw materials in percentage by mass: 2-10% of prednisone acetate, 15-75% of cinnamaldehyde and the balance of pharmaceutical filling adjuvant materials, and the compound preparation for treating the rheumatic arthritis is in the dosage form of dropping pills, tablets or capsules. The compound preparation disclosed by the invention is prepared by combining the cinnamaldehyde, which serves as a main medicinal component in a traditional Chinese medicine, namely cortex cinnamomi, and the prednisone acetate as raw materials. The preparation has functions of resisting inflammation and relieving pain, dispelling wind and eliminating dampness, warming channel and expelling cold. Compared with existing anti-rheumatic drugs, the compound preparation, which is the combination of the cinnamaldehyde and the prednisone acetate, not only can reduce the side effects of the prednisone acetate but also can improve a curative effect. The preparation, on treating the rheumatic arthritis, has the characteristics of being significant in curative effect, short in treatment course, not easy for recurrence and the like, and the preparation has the advantages of being simple in preparation process, controllable in quality, convenient to take and carry and the like; and a finished product (the compound preparation) is good in market development prospect.

Description

technical field [0001] The invention relates to a compound preparation, in particular to a compound preparation for treating rheumatoid arthritis. Background technique [0002] Rheumatoid arthritis is a kind of allergic disease related to group A beta hemolytic streptococcus infection, and it is one of the main manifestations of rheumatic fever, which is more common in adults. Rheumatoid arthritis often starts with acute fever and joint pain. The typical manifestations are mild or moderate fever, migratory polyarthritis, and the affected joints are mostly knees, ankles, shoulders, elbows, wrists and other large joints. Commonly caused by One joint is transferred to another joint, and the local lesion is red, swollen, hot, and severe pain. Some patients also have several joints at the same time. Atypical patients only have joint pain without other inflammatory manifestations. Acute inflammation usually occurs within 2-4 days. Week subsides, does not stay sequelae, but often ...

Claims

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Application Information

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IPC IPC(8): A61K31/573A61K31/11A61P19/02A61P29/00
CPCA61K31/573A61K31/11A61K2300/00
Inventor 杨武亮谭舒舒胡源祥宋玉鹏陈海芳罗小泉袁金斌
Owner JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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