Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of Viola yedoensis in preparation of drug for preventing and treating infection of dengue II viruses

A technology of violetidine and virus infection, applied in the directions of antiviral agents, pharmaceutical formulations, plant raw materials, etc., to achieve the effect of preventing and treating dengue fever infection

Active Publication Date: 2016-08-31
GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no report on the anti-dengue virus activity of violadin and its application in anti-dengue virus in the literature.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of Viola yedoensis in preparation of drug for preventing and treating infection of dengue II viruses
  • Application of Viola yedoensis in preparation of drug for preventing and treating infection of dengue II viruses

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0040] Take 10kg of dried whole herb of Viola chinensis, soak in 100L of distilled water for 30 minutes, decoct for 30 minutes, filter while hot, concentrate to a thick extract with a specific gravity of 1.05-1.1, and dry to obtain the water extract of Viola chinensis.

example 2

[0041] Example 2: (granules)

[0042] Get 300g of the water extract of Example 1, add auxiliary materials such as sucrose and dextrin, place in a fluidized granulator for mixing, granulate, dry, and pack, 9g per bag. This product is brown-green granule with slightly sweet and bitter taste. Other items should comply with the relevant provisions of the 2010 edition of the Pharmacopoeia of the People's Republic of China under the granules.

example 3

[0043] Example 3: (capsules)

[0044] Take 300 g of the water extract of Example 1, add auxiliary materials such as starch, place in a boiling granulator, mix, granulate, and dry. The obtained granules are packed into No. 1 hard gelatin capsules, each 0.3 g, divided into 100 capsules. This product is a capsule, the content is brown-green granules or powder, slightly bitter taste, for oral use. Other items should comply with the relevant regulations under the capsules of the Pharmacopoeia of the People's Republic of China 2010 Edition.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to application of Viola yedoensis in preparation of a drug for preventing and treating infection of dengue II viruses. According to the application, a Viola yedoensis aqueous extract is capable of obviously inhibiting the dengue II viruses and can be used for treating the drug for preventing and treating the infection of the dengue II viruses. The drug for preventing and treating the infection of the dengue II viruses is a clinically acceptable solid or liquid oral preparation prepared from the Viola yedoensis aqueous extract and a conventional dosage of medically acceptable auxiliary materials.

Description

technical field [0001] The invention relates to a pharmaceutical preparation containing an undetermined structure from a plant, in particular to a new application of Viola Viola plant of Viola family Viola in pharmacy. Background technique [0002] Dengue virus belongs to Flaviviridae and Flavivirus genus in classification. Including 4 different serotypes, namely type Ⅰ, Ⅱ, Ⅲ, Ⅳ dengue virus. Dengue fever is an acute infectious disease caused by dengue virus. It is mainly transmitted by Aedes aegypti and Aedes albopictus. The main clinical manifestations are high fever, headache, muscle and joint pain, rash, enlarged lymph nodes and leukopenia, etc. In severe cases, hemorrhage or shock may occur, and even death. The disease is mainly prevalent in tropical and subtropical regions. Currently, cases have occurred in more than 100 countries and regions around the world, and about 2.5 to 3 billion people are at risk of dengue virus infection. The disease has seriously affected...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/86A61P31/14
CPCA61K36/86A61K2236/331A61K2236/51A61K2236/53Y02A50/30
Inventor 李耿赖小平吴建国
Owner GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com