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Degradable anastomosis pin in living body and production process for degradable anastomosis pin

A production process and staple technology, which are applied in the field of biodegradable staples and their production processes, can solve the problem that staple materials cannot take into account the plastic deformation ability and corrosion resistance, and achieve the requirements of ensuring biological safety and satisfying the corrosion rate. Requirements, good blood compatibility

Active Publication Date: 2016-11-09
CHANGZHOU WASTON MEDICAL APPLIANCE CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] The purpose of the present invention is to solve the problem that current staple materials cannot take into account both good plastic deformation ability and high corrosion resistance, and to provide a biomaterial with high corrosion resistance, good plastic deformation ability and good biocompatibility. Degradable staple and its production process

Method used

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  • Degradable anastomosis pin in living body and production process for degradable anastomosis pin
  • Degradable anastomosis pin in living body and production process for degradable anastomosis pin

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Embodiment Construction

[0042] The present invention will now be described in further detail.

[0043] A biodegradable staple, the composition of its components by mass percentage is shown in the following table:

[0044]

[0045] A production process of biodegradable staples, comprising the following steps:

[0046] 1) Weigh each component in proportion;

[0047] 2) Dry the components weighed above in an oven at 100°C for 1-2 hours;

[0048] 3) Add the weighed Zn, Mn, Sn, Ag and Mg into the graphite crucible, after vacuuming, pass it into the BF 6 and CO 2 The mixed gas is used as a protective gas, and the components are completely dissolved under the condition of 700-800°C, and then kept for 10-20min.

[0049] 4) Add HA powder into a graphite crucible containing Zn, Mn, Sn, Ag and Mg for melting, and stir evenly to obtain a melting solution;

[0050] 5) Pour the smelting solution into a pre-dried graphite mold to obtain a magnesium alloy ingot;

[0051] 2. Heat treatment process of magnesium...

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Abstract

The invention relates to the technical field of tissue engineering, in particular to a degradable anastomosis pin in a living body and a production process for the degradable anastomosis pin. The anastomosis pin consists of the following components in percentage by mass: 2-6% of Zn, 2-5% of Mn, 0.1-1% of Sn, 1.5-2% of Ag, 0.5-2% of HA powder and the balance Mg. The degradable anastomosis pin in the living body can be naturally degraded in the living body, i.e., is degraded in the body within certain time after medical effect is achieved, so that economical burden and body burden, caused by second operation, on a patient are avoided; Al and rare-earth metal are avoided in aspect of component design, and biological safety of materials are guaranteed in aspect of material selection; the degradable anastomosis pin has high corrosion resistance, good plastic deformation capacity and good biocompatibility, and meets requirements, on a corrosion rate, of internal implant materials; and moreover, the degradable anastomosis pin is free of obvious cell toxicity and is good in blood compatibility, and can meet the requirements, on biocompatibility, of the internal implant materials.

Description

technical field [0001] The invention relates to the technical field of tissue engineering, in particular to a biodegradable staple and a production process thereof. Background technique [0002] Medical metal materials will still occupy an important position in the field of biomaterials in the future, because medical metal materials have excellent mechanical properties. 316L stainless steel, titanium and titanium alloys, and Co-Cr alloys have been widely used for their excellent mechanical properties. However, a common problem in existing metal implant materials such as stainless steel and titanium alloy is poor mechanical compatibility with biological bone. The tensile strength of stainless steel, titanium alloy, etc. is more than 5 times higher than that of natural bone, and the elastic modulus is more than 10 times higher. Such materials can produce a great "stress shielding" effect on local bone tissue after being implanted in the human body. Due to the decreased stre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C22C23/04C22C23/00C22C1/02C22F1/06A61L31/02A61L31/14
CPCA61L31/022A61L31/028A61L31/148C22C1/02C22C23/00C22C23/04C22F1/06
Inventor 周建良吴伟敏戴明凯
Owner CHANGZHOU WASTON MEDICAL APPLIANCE CO LTD
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