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Estimation method of HIFU damage shear wave elastic properties based on lk optical flow method

An elastic characteristic and shear wave technology, which is applied in the directions of acoustic wave diagnosis, infrasonic wave diagnosis, ultrasonic/sonic wave/infrasonic wave diagnosis, etc., can solve problems such as low signal-to-noise ratio, poor real-time performance, and low image resolution of ultrasonic imaging equipment, and achieve high sensitivity High performance, good real-time performance and good robustness

Active Publication Date: 2017-08-01
永春县产品质量检验所福建省香产品质量检验中心国家燃香类产品质量监督检验中心福建
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Problems solved by technology

However, there are some problems in using ultrasound to track the shear wave of acoustic radiation force: 1. The vibration displacement of the shear wave induced by ultrasonic excitation is on the order of microns, and its echo is easily disturbed by noise and the movement of the organism itself; 2. The existing ultrasonic equipment The signal-to-noise ratio is low, and the accuracy of the measured vibration displacement results is low; 3. The image resolution of the ultrasonic imaging equipment is low, and it is difficult to ensure the resolution and contrast of the elastic image; 4. The use of ultrasound to track shear waves Poor real-time performance

Method used

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  • Estimation method of HIFU damage shear wave elastic properties based on lk optical flow method
  • Estimation method of HIFU damage shear wave elastic properties based on lk optical flow method
  • Estimation method of HIFU damage shear wave elastic properties based on lk optical flow method

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Embodiment Construction

[0040] The shear elastic modulus μ of the polyacrylamide gel phantom containing bovine serum albumin (BSA) and the shear wave velocity c in the phantom are known t , the Young's modulus of elasticity E of the BSA phantom, and the shear wave velocity c in the phantom t The relationship is as follows:

[0041]

[0042]

[0043] in:

[0044] c t ——Shear wave velocity / m s -1 ;

[0045] ρ——The density of the medium / kg·m -3 ;

[0046] μ——shear modulus of elasticity / kPa;

[0047] E——Young's modulus of elasticity / kPa.

[0048] It can be seen from the above two formulas that under the premise that the density of the BSA phantom is known, the shear elasticity of the phantom can be quantitatively estimated by measuring the shear wave velocity in the phantom.

[0049]In order to obtain the shear wave velocity in the medium, the present invention adopts the peak time algorithm, i.e. TTP (time-to-peak) algorithm: select two known distances (usually 0.5mm- 1mm) mark points, dr...

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Abstract

The invention discloses an HIFU damage shear wave elastic characteristic estimation method based on LK optical flow. A damage formation and vibration continuous image is obtained with a high-speed camera when HIFU acts on tissue phantom, a vibration displacement curve of damage is obtained with the Lucas-Kanade optical flow method of an image pyramid, the propagation speed of acoustic radiation force shear wave generated on damage under the action of HIFU is calculated with the time-to-peak (TTP) method, quantitative estimation of shear elasticity modulus of damage can be conducted according to the relation among medium density, shear wave velocity in medium and medium shear elasticity modulus, and then the elastic characteristic of target tissue during treatment is monitored in real time and treatment effect is evaluated.

Description

technical field [0001] The invention belongs to the technical field of ultrasonic imaging, and in particular relates to a system and method for tracking shear waves and estimating elastic characteristics of high-intensity focused ultrasound (HIFU) thermal damage based on the LK pyramid optical flow method. Background technique [0002] High-intensity focused ultrasound (HIFU) therapy is one of the most promising new tumor treatment methods. Because of its non-invasive and precise treatment of deep target tissues, it has been clinically used in various tumor treatments. HIFU treatment focuses the high-energy ultrasonic beam emitted by the ultrasonic transducer on the target area of ​​the organism, and generates a transient high temperature above 60°C at the focus of the ultrasonic focus, and destroys the target area tissue after a few seconds through the thermal effect without damaging the surrounding area. organization to achieve therapeutic goals. The pathological changes ...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B8/08A61B8/00
CPCA61B8/08A61B8/52
Inventor 陆明珠张灵璐高雅马风超黄伟骏王睿万明习
Owner 永春县产品质量检验所福建省香产品质量检验中心国家燃香类产品质量监督检验中心福建
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