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Chlorophyll ointment for preventing and treating mosquito bite, and preparation method thereof

A technology of mosquito bites and chlorophyll, applied in the field of medicine, can solve the problems of inconspicuous therapeutic effect and low absorption rate, and achieve significant mosquito repellent effect, reduce ear weight difference, and high transdermal absorption rate

Active Publication Date: 2016-12-21
GUANGDONG COOWAY BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] However, the current anti-mosquito bite ointment has a low ointment absorption rate, needs to be used for a long time, and the therapeutic effect is not obvious

Method used

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  • Chlorophyll ointment for preventing and treating mosquito bite, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1, a kind of chlorophyll ointment of prevention and treatment mosquito bite

[0033] The chlorophyll ointment for preventing and controlling mosquito bites consists of the following components and their weight percentages:

[0034] Chlorophyll 10%, Nuciferine 8%, Syringic Acid 4%, Oil Phase Base 24%, Emulsifier 10%, Penetration Enhancer 6%, Ethyl p-hydroxybenzoate 0.1% and Water 37.9%; It is composed of beeswax, lecithin and isopropyl myristate in a weight ratio of 1:6:0.5; the emulsifier is composed of glyceryl stearate and triethanolamine in a weight ratio of 2:3; the penetration enhancer is composed of urea and menthol in a weight ratio of 2:5.

[0035] Preparation:

[0036] S1 Take the oil phase matrix and heat it to 75°C to dissolve, then add nuciferine and syringic acid, stir until completely dissolved, and obtain the oil phase liquid;

[0037] S2 Add the emulsifier into water and heat to 75°C, stir until completely dissolved to obtain an aqueous pha...

Embodiment 2

[0039] Embodiment 2, a kind of chlorophyll ointment that prevents mosquito bite

[0040] The chlorophyll ointment for preventing and controlling mosquito bites consists of the following components and their weight percentages:

[0041]Chlorophyll 16%, Nuciferine 10%, Syringic Acid 6%, Oil Phase Base 20%, Emulsifier 8%, Penetration Enhancer 4%, Ethyl p-hydroxybenzoate 0.12% and Water 35.9%; It is composed of beeswax, lecithin and isopropyl myristate in a weight ratio of 2:5:1; the emulsifier is composed of glyceryl stearate and triethanolamine in a weight ratio of 3:2; the penetration enhancer is composed of urea and menthol in a weight ratio of 3:4.

[0042] Preparation:

[0043] S1 Take the oil phase matrix and heat it to 80°C to dissolve, then add nuciferine and syringic acid, stir until completely dissolved, and obtain the oil phase liquid;

[0044] S2 Add the emulsifier into water and heat to 80°C, stir until completely dissolved to obtain an aqueous phase liquid;

[0...

Embodiment 3

[0046] Embodiment 3, a kind of chlorophyll ointment that prevents mosquito bite

[0047] The chlorophyll ointment for preventing and controlling mosquito bites consists of the following components and their weight percentages:

[0048] 20% of chlorophyll, 12% of nuciferine, 8% of syringic acid, 12% of oily base, 6% of emulsifier, 2% of penetration enhancer, 0.16% of ethyl p-hydroxybenzoate and 39.84% of water; said oily base It is composed of beeswax, lecithin and isopropyl myristate in a weight ratio of 3:4:2; the emulsifier is composed of glyceryl stearate and triethanolamine in a weight ratio of 4:1; the penetration enhancer is composed of urea and menthol in a weight ratio of 4:3.

[0049] Preparation:

[0050] S1 Take the oil phase matrix and heat it to 85°C to dissolve, then add nuciferine and syringic acid, stir until completely dissolved, and obtain the oil phase liquid;

[0051] S2 Add the emulsifier into water and heat to 85°C, stir until completely dissolved to o...

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Abstract

The invention belongs to the field of medicine, and particularly relates to a chlorophyll ointment for preventing and treating mosquito bite, and a preparation method thereof. The chlorophyll ointment mainly comprises chlorophyll, nuciferine, syringic acid, an oil phase matrix, an emulsifier, a permeation promoter, a preservative and water. According to the present invention, the chlorophyll ointment has the significant effects inflammation eliminating, itching stopping and mosquito repelling, has characteristics of high percutaneous absorption rate, high drug loading rate and high transdermal rate, can be quickly and effectively treat the mosquito bite wound, is the ideal mosquito bite preventing and treating ointment, and is easy to promote and apply.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a chlorophyll ointment for preventing mosquito bites and a preparation method thereof. Background technique [0002] Chlorophyll is the green pigment in the photosynthetic membrane, which is the main component for capturing light in photosynthesis. Chlorophyll is a general term for magnesium and nitrogen on the four pyrrole rings combined with porphyrin as the skeleton of green pigments, there are several types such as a, b, c, d and e. In recent years, green food has received widespread attention, and some physiological functions of chlorophyll in green plants have also begun to receive attention. [0003] The structure of chlorophyll is very similar to that of heme, it is easy to be absorbed by the human body, and has the function of revitalizing cells. It is widely used in medicine, food and daily chemical industry. Since chlorophyll is a natural product, it has no toxic s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/555A61K31/473A61K31/192A61K9/06A61K47/44A61K47/24A61K47/14A61K47/18A61K47/10A61K47/16A61P17/02A61P17/04A61P29/00
CPCA61K9/0014A61K9/06A61K31/192A61K31/473A61K31/555A61K47/10A61K47/14A61K47/16A61K47/18A61K47/24A61K47/44A61K2300/00
Inventor 陈松彬易萍倪彦艳刘杰森张爱萍李小翠
Owner GUANGDONG COOWAY BIOTECH CO LTD