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Traditional Chinese medicine capsules for treating femoral head necrosis

A technology for femoral head necrosis and traditional Chinese medicine capsules, which is applied in the directions of capsule delivery, medical raw materials from mollusks, medical raw materials from leeches/worms, etc., can solve problems such as unreasonable prescription compatibility, enhanced drug toxicity, and weakened therapeutic effect. , to improve microcirculation, enhance metabolism, accelerate regeneration and repair, and promote metabolism and absorption.

Inactive Publication Date: 2017-01-11
卞永兴
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the pathological mechanism of femoral head necrosis has not been fully elucidated, and various theories have been proposed for its pathogenesis, but there is no public opinion so far.
Conventional Chinese medicine treatment is difficult to take care of comprehensively with only a few herbs, and a variety of drugs must be properly combined to improve the efficacy or reduce adverse reactions, so as to adapt to the treatment of complex diseases
In view of the complex interaction of various active ingredients of various Chinese medicinal materials in the body, changes in the pharmacokinetics and pharmacodynamics of various drugs in the body will have various effects on the interaction between drugs. When used in combination, it may not only produce synergistic drug effects, but also may produce antagonistic effects, which will lead to weakening of drug therapeutic effect or treatment failure. Some drugs in combination will also increase drug toxicity and cause adverse reactions; Enhanced, but when the therapeutic effect is excessively enhanced, it will exceed the body's ability to tolerate it, and it can also cause adverse reactions and even endanger patients.
Part of the research is to prepare traditional Chinese medicine prescriptions for the treatment of femoral head necrosis. The most common problem is the unreasonable compatibility of the prescriptions. It is often only based on the individual functions and indications of some single or compound medicines and some pharmacodynamic indicators. According to the theory of medicine, the random addition and subtraction of the flavor of the prescription results in unreasonable prescriptions, which contradicts the theory of traditional Chinese medicine.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Weighing: 18 grams of Bayleaf Palm, 16 grams of tap blood, 14 grams of melon seeds, 12 grams of Hualianqi, 9 grams of Chuanxiong, 9 grams of Guizhi, 8 grams of Salvia, 8 grams of Achyranthes bidentata, 7 grams of Millet, hook 7 grams of rattan, 6 grams of mulberry, 6 grams of scorpion, 5 grams of earthworm, 5 grams of walnut kernel, 6 grams of achyranthes bidentata, 7 grams of kudzu root, 9 grams of psoralen, 9 grams of drynaria, 10 grams of dog spine, 10 grams of epimedium, 8 grams of oyster, 8 grams of herb, 6 grams of Bupleurum, 7 grams of angelica, 8 grams of licorice, and 6 grams of Artemisia japonica.

[0043] The preparation method is as follows: remove impurities from the above medicinal materials, mix them, put them in a drying oven and dry them at a temperature of 120°C, grind them into fine powders of 100-130 meshes, put them into capsules at 0.5g / capsule after ultraviolet disinfection, and obtain finished product.

[0044] Dosage: Take orally, 2 times a day...

Embodiment 2

[0061] Weighing: 16 grams of tap blood, 14 grams of melon seeds, 12 grams of Hualianqi, 9 grams of Chuanxiong, 9 grams of Guizhi, 8 grams of Danshen, 8 grams of Achyranthes bidentata, 7 grams of Milletah, 7 grams of Uncaria, and mulberry 6 grams, 6 grams of scorpion, 5 grams of earthworm, 5 grams of walnut kernel, 6 grams of Achyranthes bidentata, 7 grams of kudzu root, 9 grams of psoralen, 9 grams of drynaria, 10 grams of dog spine, 10 grams of epimedium, 8 grams of oysters, 8 grams of herb, 6 grams of Bupleurum, 7 grams of angelica, 8 grams of licorice. The preparation method is the same as in Example 1.

[0062] Among the 10 patients with femoral head necrosis who selected the Chinese medicine capsules made in Example 2 of the present invention, 6 cases were cured, 2 cases took a turn for the better, 2 cases did not heal, and 0 cases had adverse reactions. The cure rate was 60%, and the total effective rate was 80%. The average healing time is 21 days. The cured and impro...

Embodiment 3

[0064] Weighing: 16 grams of tap blood, 12 grams of Hualianqi, 9 grams of Chuanxiong, 9 grams of Guizhi, 8 grams of Salvia, 8 grams of Achyranthes bidentata, 7 grams of Milletah, 7 grams of Uncaria, 6 grams of Sangji, Scorpion 6 grams, 5 grams of earthworm, 5 grams of walnut kernel, 6 grams of achyranthes, 7 grams of kudzu root, 9 grams of psoralen, 9 grams of drynaria, 10 grams of dog spine, 8 grams of oysters, 8 grams of atractylodes, 6 grams of Bupleurum gram, 7 grams of angelica, 8 grams of licorice. The preparation method is the same as in Example 1.

[0065] Among the 10 femoral head necrosis patients who selected the Chinese medicine capsules made by the embodiment of the present invention 3, 5 cases were cured, 2 cases took a turn for the better, 3 cases were unhealed, 0 cases had adverse reactions, the cure rate was 50%, and the total effective rate was 70%. The average healing time is 23 days. The cured and improved patients were followed up for 24 months, and 1 ca...

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PUM

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Abstract

The invention discloses traditional Chinese medicine capsules for treating femoral head necrosis. The capsules are prepared from the following traditional Chinese medicinal materials by weight: 18 parts of corypha umbraculifera, 16 parts of all-grass of ophiorrhiza umbricola, 14 parts of muskmelon seeds, 12 parts of polygonum runcinatum, 9 parts of chuanxiong rhizomes, 9 parts of cassia twigs, 8 parts of red sage roots, 8 parts of twotooth achyranthes roots, 7 parts of suberect spatholobus stems, 7 parts of uncaria, 6 parts of Chinese taxillus herbs, 6 parts of scorpions, 5 parts of earthworms, 5 parts of walnut kernels, 6 parts of twotooth achyranthes roots, 7 parts of kudzuvine roots, 9 parts of malaytea scurfpea fruits, 9 parts of fortune's drynaria rhizomes, 10 parts of cibot rhizomes, 10 parts of epimedium herbs, 8 parts of oysters, 8 parts of atractylodes rhizomes, 6 parts of Chinese thorowax roots, 7 parts of Chinese angelica, 8 parts of licorice roots and 6 parts of hairy wormwood herbs. Clinical experiments prove that by means of rational compatibility of the traditional Chinese medicinal materials, the femoral head necrosis can be treated and not easy to relapse, the capsules take effect quickly, and the overall adjustment effect and the long-term effect are realized.

Description

technical field [0001] The invention relates to a traditional Chinese medicine capsule, in particular to a traditional Chinese medicine capsule for treating femoral head necrosis. Background technique [0002] Avascular necrosis of the femoral head is a disease in which the blood supply vessels of the femoral head are damaged or interrupted, causing the apoptosis of bone cells, which in turn leads to changes in the bone structure of the femoral head, and then develops into a disease of femoral head collapse and joint dysfunction. It is one of the more common bone and joint difficult diseases in clinical practice. At present, osteonecrosis of the femoral head has been widely studied by orthopedic doctors, and various theories have been put forward for its etiology and pathogenesis. Trauma, long-term steroid use, and excessive alcohol consumption have been widely recognized as the most common causes of osteonecrosis of the femoral head. However, the pathological mechanism of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61K9/48A61P19/08A61K35/646A61K35/62A61K35/618
CPCA61K36/889A61K9/48A61K35/618A61K35/62A61K35/646A61K36/11A61K36/126A61K36/185A61K36/21A61K36/232A61K36/233A61K36/236A61K36/282A61K36/284A61K36/296A61K36/42A61K36/484A61K36/486A61K36/487A61K36/488A61K36/52A61K36/537A61K36/54A61K36/704A61K36/74A61K2300/00
Inventor 卞永兴其他发明人请求不公开姓名
Owner 卞永兴
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