Method of using electronic tongue to rapidly detect bitterness of berberine hydrochloride

A technology of berberine hydrochloride and electronic tongue, which is applied in the field of food science, can solve problems such as poor repeatability, and achieve the effects of short detection time, simple detection conditions, and small sample volume

Inactive Publication Date: 2017-04-19
SHANGHAI INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Aiming at the above-mentioned technical problems in the prior art, the present invention provides a kind of method that detects the bitter taste of berberine hydrochloride quickly with electronic tongue, described this method that detects the bitter taste of berberine hydrochloride fast with electronic tongue will solve the problem of traditional sensory In the evaluation, the sensory evaluation is highly subjective and has poor repeatability

Method used

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  • Method of using electronic tongue to rapidly detect bitterness of berberine hydrochloride
  • Method of using electronic tongue to rapidly detect bitterness of berberine hydrochloride
  • Method of using electronic tongue to rapidly detect bitterness of berberine hydrochloride

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Embodiment 1

[0028] An evaluation method for rapidly detecting the bitterness of medicines with an electronic tongue, comprising the steps of:

[0029] 1. Preparation of berberine hydrochloride standard solution as test sample

[0030] According to ISO3972 regulations, prepare berberine hydrochloride standard solution. First, take 20-25 mg of berberine hydrochloride, dilute to 100 mL with distilled water, and prepare a 0.2-0.25 g / L berberine hydrochloride solution. Use a 10mL pipette to draw 1mL, 2mL, 3mL, 4mL, 5mL, 6mL, 7mL, 8mL, 9mL, 10mL of 0.25g / L berberine hydrochloride solution, and dilute to 100mL with distilled water to prepare 0.0025g / L , 0.0050g / L, 0.0075g / L, 0.0100g / L, 0.0125g / L, 0.0150g / L, 0.0175g / L, 0.0200g / L, 0.0225g / L, 0.0250g / L ten groups of hydrochloric acid Berberine standard solution.

[0031] 2. Establish an electronic tongue sensor array, collect measurable electrical signals, generate taste fingerprint information, extract characteristic data from taste fingerprint...

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Abstract

The invention discloses a method of using an electronic tongue to rapidly detect the bitterness of berberine hydrochloride. The method comprises the following steps: preparing a standard solution of berberine hydrochloride; establishing an electronic tongue sensor array; pouring the standard solution into a special electronic tongue cup, putting an electronic tongue into a prepared sample to preheat the sensors, then putting the electronic tongue into a sample solution to collect the sample signals so as to obtain a corresponding LDA map and PCA map of the electronic tongue; obtaining the response value of the electronic tongue; subjecting the standard solution to qualitative analysis by means of PCA principal component analysis and LDA discrimination function analysis to obtain a map representing the relationship between the bitterness levels and the response values of the electronic tongue; detecting the berberine hydrochloride sample solution, and obtaining the bitterness level of the sample solution according to the relationship map. The provided method has the advantages that high prediction precision and simple operation, and cannot be easily influenced by external factors.

Description

technical field [0001] The invention belongs to the field of food science, and relates to berberine hydrochloride, in particular to a method for quickly detecting the bitterness of berberine hydrochloride with an electronic tongue. Background technique [0002] Berberine hydrochloride, also known as berberine, is an isoquinoline alkaloid mainly found in Berberidaceae plants such as Coptidis Rhizoma and Cortex Phellodendri. Berberine hydrochloride has been widely used in the treatment of intestinal infection, suppurative otitis media, bacillary dysentery, etc. Studies have shown that it also has a certain effect on tuberculosis, respiratory tract infection, acute tonsillitis and other diseases. [0003] With the urgent requirements for the evaluation and quality control of food and drug taste in the food and drug industry, there is an increasing demand for objective and rapid analytical diagnostic instruments such as electronic tongues. Strong practical significance. [000...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/416G01N33/00
CPCG01N27/416G01N33/0001
Inventor 冯涛王慧庄海宁陈忠秋王文欣王旭增赵宇曾小兰张三丰王晶晶吴阳童彦尊
Owner SHANGHAI INST OF TECH
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