Surface enhanced fiber Raman probe

A Raman probe and surface enhancement technology, applied in Raman scattering, material analysis through optical means, measurement devices, etc., can solve problems such as low excitation efficiency and weak light field, and achieve low cost, simple manufacture, and easy operation. Convenient and flexible effects

Active Publication Date: 2017-04-26
GUILIN UNIV OF ELECTRONIC TECH
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Problems solved by technology

Most of these probes use the evanescent field transmitted in the optical fiber as the Raman excitation light. Although the active area is large, the optical field

Method used

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  • Surface enhanced fiber Raman probe
  • Surface enhanced fiber Raman probe
  • Surface enhanced fiber Raman probe

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Embodiment Construction

[0026] The surface-enhanced optical fiber Raman probe of the present invention adopts a coaxial dual-waveguide channel optical fiber, prepares a layer of metal nano-layer on the end face of the coaxial dual-waveguide channel optical fiber, and then adopts a fine grinding method to micronize the end face of the optical fiber. Processing to form a rotationally symmetrical truncated cone or an internal reflective structure of an arc-shaped truncated cone. The invention can realize in-situ excitation and acquisition of precisely positioned surface-enhanced Raman spectra, and is especially suitable for contact-type Raman scattering excitation of living cell tissues.

[0027] The present invention will be further described below in conjunction with specific drawings.

[0028] The present invention adopts Figure 1a The coaxial dual-waveguide channel fiber shown in, Figure 1b It represents the distribution of the optical fiber refractive index n along with the radius r. The optica...

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Abstract

The invention provides a surface enhanced fiber Raman probe. A metal nano-layer used for surface enhancement is prepared at the fiber end of a coaxial double-waveguide channel fiber, then the fiber end is finely ground to form an arc frustum playing the role of reflecting and converging exciting light in an annular core, and the converged exciting light is just positioned on the metal nano-layer, so that the exciting light and a substance to be tested at the contact point of the end surface of the probe are sufficiently interacted. When the exciting light passes through the metal nano-layer, surface enhancement Raman signals are generated by assistance of stimulation of surface plasma waves and the interaction with detected substances, so that the detection sensitivity of the fiber Raman probe is greatly improved. The surface enhanced fiber Raman probe can be used for the accurate positioning contact type measurement of a surface enhanced Raman spectrum, and is particularly suitable for the acquisition and measurement of a positioning contact type surface enhanced Raman spectrum of living cell tissues.

Description

technical field [0001] The invention relates to an optical fiber Raman probe, in particular to a surface-enhanced optical fiber Raman probe which can be used for in-vivo intervention and positioning contact acquisition of living cells of surface-enhanced Raman spectroscopy. Background technique [0002] The surface-enhanced Raman scattering effect refers to the phenomenon that the substance to be tested is adsorbed on the surface of the substrate with a rough metal nanolayer, thereby greatly enhancing the intensity of the Raman spectrum of the substance to be tested. In recent years, surface-enhanced Raman spectroscopy has been widely used in biochemical analysis, environmental monitoring, food safety and other fields. [0003] The combination of surface-enhanced Raman scattering effect and optical fiber is a research hotspot in recent years. On the one hand, the surface-enhanced Raman effect can enhance the Raman signal of the substance to be measured by several orders of ...

Claims

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Application Information

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IPC IPC(8): G01N21/65
CPCG01N21/658
Inventor 苑立波杨世泰
Owner GUILIN UNIV OF ELECTRONIC TECH
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