Phytosterol compound lipid-decreasing formula and preparation method for tablet thereof

The technology of phytosterol and tablet is applied in the field of phytosterol compound lipid-lowering formula and tablet preparation field, which can solve the problems of single action mode, poor tablet stability, poor solubility of phytosterol and the like, and achieves improved effect, The effect of improving stability

Pending Publication Date: 2017-05-10
广州莱可福生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the solubility of phytosterols is not good, and the absorption rate of healthy people is usually less than 5% of the content in food, far lower than the 35-70% absorption rate of cholesterol
[0005] Existing ph...

Method used

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  • Phytosterol compound lipid-decreasing formula and preparation method for tablet thereof
  • Phytosterol compound lipid-decreasing formula and preparation method for tablet thereof
  • Phytosterol compound lipid-decreasing formula and preparation method for tablet thereof

Examples

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Embodiment 1

[0028] The phytosterol compound lipid-lowering formula of the present embodiment includes the following components: by weight, 15 parts of phytosterol, 5 parts of soybean peptide, 5 parts of β-glucan, 1 part of lecithin, and 10 parts of mannitol , 1 part of maltodextrin, 0.01 part of sucralose and 5 parts of microcrystalline cellulose.

[0029] The tablet preparation method of the phytosterol compound lipid-lowering prescription of the present embodiment comprises the following steps:

[0030] Step 1, take 15 parts of phytosterol, 5 parts of soybean peptide, 5 parts of β-glucan, 1 part of lecithin, 10 parts of mannitol, 1 part of maltodextrin, 0.01 part of sucralose and 5 parts of microcrystalline cellulose Mix and stir evenly to obtain a mixture;

[0031] Step 2, adding 50% ethanol solution to the mixture and performing wet granulation with a wet granulator to obtain wet granules;

[0032] Step 3, drying the wet granules in a hot air circulation oven at 50°C to obtain dry g...

Embodiment 2

[0036] The phytosterol compound lipid-lowering formula of the present embodiment includes the following components: in parts by weight, 30 parts of phytosterols, 20 parts of soybean peptides, 15 parts of β-glucan, 10 parts of lecithin, and 30 parts of mannitol , 10 parts of maltodextrin, 0.5 parts of sucralose and 15 parts of microcrystalline cellulose.

[0037] The tablet preparation method of the phytosterol compound lipid-lowering prescription of the present embodiment comprises the following steps:

[0038] Step 1: Take 30 parts of phytosterol, 20 parts of soybean peptide, 15 parts of β-glucan, 10 parts of lecithin, 30 parts of mannitol, 10 parts of maltodextrin, 0.5 parts of sucralose and microcrystalline cellulose 15 parts of the element were mixed and stirred evenly to obtain a mixture;

[0039] Step 2, adding 60% ethanol solution to the mixture and using a wet granulator to carry out wet granulation to obtain wet granules;

[0040] Step 3, drying the wet granules in ...

Embodiment 3

[0044] The phytosterol compound lipid-lowering prescription of the present embodiment includes the following components: by weight, 70 parts of phytosterols, 50 parts of soybean peptides, 30 parts of β-glucan, 20 parts of lecithin, and 70 parts of mannitol , 30 parts of maltodextrin, 1 part of sucralose and 30 parts of microcrystalline cellulose.

[0045] The tablet preparation method of the phytosterol compound lipid-lowering prescription of the present embodiment comprises the following steps:

[0046] Step 1: Take 70 parts of phytosterol, 50 parts of soybean peptide, 30 parts of β-glucan, 20 parts of lecithin, 70 parts of mannitol, 30 parts of maltodextrin, 1 part of sucralose and microcrystalline cellulose Mix and stir 30 parts of plain ingredients evenly to obtain a mixture;

[0047] Step 2, adding 75% ethanol solution to the mixture and using a wet granulator to carry out wet granulation to obtain wet granules;

[0048] Step 3, drying the wet granules in a hot air circ...

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Abstract

The invention discloses a phytosterol compound lipid-decreasing formula and a preparation method for a tablet thereof. The formula comprises the following components in parts by weight: 15-70 parts of phytosterol, 5-50 parts of soybean peptide, 5-30 parts of beta-glucosan, 1-20 parts of lecithin, 10-70 parts of mannite, 1-30 parts of maltodextrin, 0.01-1 part of sucralose and 5-30 parts of microcrystalline cellulose. The preparation method for the tablet thereof comprises the following steps: mixing and stirring; performing wet granulation; drying; stabilizing grain size; and pressing into the tablet, thereby acquiring the tablet of the formula. The invention has the beneficial effects that the formula has an excellent lipid-decreasing effect, is capable of effectively reducing the blood lipid level of hyperlipidemia patient and has a lipid-decreasing healthcare function; the tablet prepared according to the preparation method for the tablet tastes nice; the tablet is high in stability.

Description

technical field [0001] The invention relates to the field of health food, in particular to a phytosterol compound lipid-lowering prescription and a tablet preparation method thereof. Background technique [0002] Blood lipid is a general term for total cholesterol (TC), triglyceride (TG) and lipids (such as phospholipids) in plasma. Hyperlipidemia refers to excessive blood lipid levels, which are specifically manifested as elevated levels of TC, TG, and LDL-C (low-density lipoprotein cholesterol), and decreased levels of HDL-C (high-density lipoprotein cholesterol). [0003] Hyperlipidemia often causes some diseases that seriously endanger human health, such as atherosclerosis, coronary heart disease, cerebral thrombosis, cerebral hemorrhage, pancreatitis, etc., especially among middle-aged and elderly people. Therefore, both at home and abroad attach great importance to the research and treatment of blood lipid lowering. [0004] Phytosterols are commonly used lipid-lower...

Claims

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Application Information

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IPC IPC(8): A23L33/11A23L33/18A23L33/115A23L33/125A23L29/30A23L29/00
Inventor 钟伟杰
Owner 广州莱可福生物科技有限公司
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