A kind of preparation method of n-(1-imino-2,2-dinitroethyl)-2,2-dinitroacetamide potassium salt
A technology of dinitroacetamide and dinitroethyl, which is applied in the field of preparation of N--2,2-dinitroacetamide potassium salt, can solve the problem of no N- and the like, and can ensure safety and good heat dissipation. effect, the effect of improving process safety
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Embodiment 1
[0028] The peristaltic pump is used as the continuous conveying equipment for liquid materials, and the liquid material conveying pipeline adopts polytetrafluoroethylene pipes with an inner diameter of 2 mm. Prepare nitric-sulfur mixed acid in advance according to the volume ratio of concentrated sulfuric acid and fuming nitric acid at 1:1, and cool to room temperature. Weigh 5.0g of 2-methyl-4,6-dihydroxypyrimidine and 3.0g of potassium nitrate into a 500ml three-neck flask, add dichloromethane 3 times the mass of 2-methyl-4,6-dihydroxypyrimidine , start the agitator, control the temperature of the reaction material to -5 ~ 5 ° C, add 50 ml of nitric acid mixed acid at a rate of 0.5 ml / min, monitor the temperature of the material during the dropwise addition, and prevent the temperature of the material from rising by reducing the rate of addition , to ensure that the temperature of the material does not exceed 15°C. After adding nitric sulfur mixed acid, continue to nitrate ...
Embodiment 2
[0030] The peristaltic pump is used as the continuous conveying equipment for liquid materials, and the liquid material conveying pipeline adopts polytetrafluoroethylene pipes with an inner diameter of 3 mm. Prepare mixed nitric acid in advance according to the volume ratio of 98% concentrated sulfuric acid and fuming nitric acid at a volume ratio of 2:1, and cool to room temperature. Weigh 5.0g of 2-methyl-4,6-dihydroxypyrimidine and 1.8g of potassium sulfate into a 1000ml three-necked flask, add 10 times the mass of 2-methyl-4,6-dihydroxypyrimidine in chloroform , start the agitator, control the temperature of the reaction material to be 5-10°C, add 75ml of nitric-sulfur mixed acid at a rate of 0.5ml / min, monitor the temperature of the material during the dropwise addition, and prevent the temperature of the material from rising by reducing the rate of addition. Make sure that the temperature of the material does not exceed 15°C. After adding nitric sulfur mixed acid, conti...
Embodiment 3
[0032]The peristaltic pump is used as the continuous conveying equipment for liquid materials, and the liquid material conveying pipeline adopts polytetrafluoroethylene pipes with an inner diameter of 3 mm. Prepare mixed nitric acid in advance according to the volume ratio of 98% concentrated sulfuric acid and fuming nitric acid at a volume ratio of 1.5:1, and cool to room temperature. Weigh 5.0g of 2-methyl-4,6-dihydroxypyrimidine and 2.5g of potassium sulfate into a 1000ml three-neck flask, add tetrachloromethane 15 times the mass of 2-methyl-4,6-dihydroxypyrimidine , start the agitator, control the temperature of the reaction material to be 0-5°C, add 50ml of nitric-sulfur mixed acid at a rate of 0.5ml / min, monitor the temperature of the material during the dropwise addition, and prevent the temperature of the material from rising by reducing the rate of addition. Make sure that the temperature of the material does not exceed 10°C. After adding nitric sulfur mixed acid, co...
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