A kind of preparation method of sericin/glycerin blend film and its product and application

A technology of blending film and glycerin, which is applied in the field of biomaterials, can solve the problems of low toxicity and biocompatibility, and achieve the effects of promoting healing, strong antibacterial and growth inhibition
CN106947268BActive Publication Date: 2019-06-21SOUTHWEST UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SOUTHWEST UNIV
Publication Date
2019-06-21

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Abstract

The invention relates to a preparation method of a sericin / glycerol blend membrane as well as a production and application thereof. The preparation method comprises the following steps: mixing sericin solution with glycerol, then pouring into a mould, drying, and carrying out film formation, so that the sericin / glycerol blend membrane is obtained. The defects of brittleness and difficulty in forming of sericin can be overcome by utilizing the glycerol, and flexibility of the sericin membrane is improved, so that the sericin membrane can be mildly and softly contacted with skin; then in-situ synthesis of nanosilver is carried out on the surface of the sericin / glycerol blend membrane by virtue of a green simple method, so that a nanosilver / sericin / glycerol blend membrane with antibacterial effect is prepared, and the nanosilver / sericin / glycerol blend membrane has excellent shape, stability and mechanical properties; and meanwhile, the sericin / glycerol blend membrane has good biocompatibility and has important economic benefit and social significance.
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Description

technical field

[0001] The invention belongs to the field of biomaterials, and in particular relates to a method for preparing a sericin / glycerin blend film, and also relates to products and applications prepared by the method. Background technique

[0002] Sericin and fibroin are the main components of silk protein, and sericin accounts for 25%-30% of the total silk protein. Sericin has 18 kinds of amino acids, most of which have polar groups such as hydroxyl, carboxyl, and amino groups. These polar hydrophilic groups endow sericin with good moisture retention, hygroscopicity and reactivity. Sericin is a natural, readily available, and inexpensive protein resource. The high hydrophilicity of sericin can maintain the moist environment of the wound and absorb the wound exudate, which in turn contributes to the healing of the wound. Sericin can resist oxidation, anticoagulation, and has good biocompatibility, reactivity and biodegradability, so sericin is considered to be an...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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