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A kind of antibacterial medical excipient and preparation method thereof

A technology of auxiliary materials and cotton fibers, which is applied in the field of antibacterial medical auxiliary materials and its preparation, can solve the problems of poor liquid absorption ability and poor compatibility of antibacterial materials, achieve soft hand feeling, good biocompatibility, and improve antibacterial performance Effect

Active Publication Date: 2019-12-24
NANYANG NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation method is to heat and mix the components, and then heat and react under low vacuum. After the product is dried, it is extruded in a twin-screw extruder to obtain a modified chitosan medical antibacterial material; the antibacterial material has poor liquid absorption. , poor compatibility, not suitable for use as medical accessories

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] An antibacterial medical auxiliary material, comprising the following raw materials in parts by weight: 40 parts of cotton fiber, 15 parts of carboxymethyl chitosan, 2 parts of nano-zinc oxide, 20 parts of sodium alginate, 20 parts of sea squirrel, and 30 parts of Eupatorium , 30 parts of Daqingye and 30 parts of rhubarb.

[0032] Wherein the particle size of nano zinc oxide is 20nm.

[0033] A preparation method of an antibacterial medical auxiliary material, comprising the following steps:

[0034] (1) Pre-treat the cotton fibers first: use the QBS-80B steam explosion process test bench, place the cotton fibers in the processing chamber, maintain the steam pressure at 1.0Mpa for 100s, and then instantly launch the steam explosion and dry Finally put it into the mixed solvent mixed according to the weight ratio of 1:0.5:1 to dissolve, and obtain the cotton spinning stock solution with a mass fraction of 0.8%;

[0035] (2) Mix astragalus, Eupatorium, Folium Folium and...

Embodiment 2

[0039] An antibacterial medical auxiliary material, comprising the following raw materials in parts by weight: 42 parts of cotton fiber, 14 parts of carboxymethyl chitosan, 2.5 parts of nano-zinc oxide, 22 parts of sodium alginate, 22 parts of seaweed, and 28 parts of Eupatorium , 28 parts of Daqingye and 28 parts of rhubarb.

[0040] Wherein the particle size of nano zinc oxide is 30nm.

[0041] A preparation method of an antibacterial medical auxiliary material, comprising the following steps:

[0042] (1) Pre-treat the cotton fibers first: use the QBS-80B steam explosion process test bench, place the cotton fibers in the processing chamber, maintain the steam pressure at 1.2Mpa for 90s, and then instantly launch the steam explosion and dry Then put it into the mixed solvent mixed by weight ratio 1: 1.5: 2 to dissolve, and obtain the cotton spinning stock solution with a mass fraction of 0.9%;

[0043] (2) Mix the seaweed, Eupatorium, Daqingye and rhubarb, crush them to 90 m...

Embodiment 3

[0047] An antibacterial medical auxiliary material, comprising the following raw materials in parts by weight: 44 parts of cotton fiber, 13 parts of carboxymethyl chitosan, 3 parts of nano-zinc oxide, 24 parts of sodium alginate, 24 parts of sea squirrel, and 26 parts of Eupatorium , 26 parts of Daqingye and 26 parts of rhubarb.

[0048] Wherein the particle size of nano zinc oxide is 40nm.

[0049] A preparation method of an antibacterial medical auxiliary material, comprising the following steps:

[0050] (1) Pre-treat the cotton fibers first: use the QBS-80B steam explosion process test bench, place the cotton fibers in the processing chamber, maintain the steam pressure at 1.4Mpa for 80s, and then eject the steam explosion instantly, dry Finally, put it into the mixed solvent mixed by weight ratio 1: 1.5: 3 to dissolve, and obtain a cotton spinning stock solution with a mass fraction of 1.0%;

[0051] (2) Mix the seaweed, Eupatorium, Daqingye and rhubarb, crush them to 1...

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Abstract

The invention discloses an anti-bacterial medical auxiliary material and a preparation method thereof, and belongs to the field of a medical auxiliary material. The anti-bacterial medical auxiliary material is prepared from the following raw materials in parts by weight: 40 to 50 parts of cotton fibers, 10 to 15 parts of carboxymethyl chitosan, 2 to 3 parts of nano zinc oxide, 20 to 30 parts of sodium alginate, 20 to 30 parts of cuttle bone, 20 to 30 parts of herba lycopi, 20 to 30 parts of folium isatidis and 20 to 30 parts of radix et rhizoma rhei. According to the anti-bacterial medical auxiliary material, the cotton fibers and the sodium alginate are blended; the carboxymethyl chitosan, the nano zinc oxide and extracts of traditional Chinese medicine are added; the cotton fibers are pre-processed; the preparation method is improved; moisture absorption performance and anti-bacterial performance of medical dressing are greatly improved.

Description

technical field [0001] The invention relates to the field of medical auxiliary materials, in particular to an antibacterial medical auxiliary material and a preparation method thereof. Background technique [0002] Medical dressings are one of the most commonly used medical supplies in hospitals. Medical dressings are wound-wrapping supplies, medical materials used to cover wounds or other damaged parts, generally referring to gauze or non-woven fabrics or cotton, etc., which can protect wounds from mechanical damage. Sexual injury, prevent wound infection, promote wound healing as soon as possible. [0003] Chinese Patent Publication No. CN 101791425 B discloses an antibacterial and healing-promoting gel material for preparing medical wound dressings and a preparation method thereof. Antibacterial and healing-promoting gel materials for preparing medical wound dressings, including natural gelling agents, chitosan, bioactive substances, soluble silver salts and organic acid...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/40A61L15/28A61L15/18A61L15/44A61L15/46A61L15/42A61K36/855A61K36/708A61P31/04A61P17/02A61K35/618
CPCA61K35/618A61K36/195A61K36/315A61K36/53A61K36/704A61K36/708A61K36/855A61K2236/333A61K2236/39A61K2236/51A61L15/18A61L15/28A61L15/40A61L15/42A61L15/44A61L15/46A61L2300/30A61L2300/404A61L2300/412A61L2300/45C08L5/04C08L5/08A61K2300/00
Inventor 马勤阁魏荣锐柳文敏桑志培刘光印
Owner NANYANG NORMAL UNIV
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