Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

An application of hydroxypropyl methyl cellulose in upper gastrointestinal tract mucous membrane damage nursing

A technology of hydroxypropyl methylcellulose and sodium carboxymethylcellulose, which is applied in the application field of hydroxypropyl methylcellulose in the care of upper gastrointestinal mucosal injury, and can solve the problem of slow onset of action and local damage The problem of drug use and large amount of drug in the mucosal part of the skin can be solved, and the effect of long duration, good film-forming effect and strong adhesion can be achieved.

Active Publication Date: 2017-08-15
HEFEI JIUYAN MEDICINE TECH DEV
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, anti-inflammatory drugs are mostly used in the treatment of esophageal mucosal injuries. They are administered through the gastrointestinal tract, injection or intravenous infusion, and are basically administered systemically. The dosage is large, and the drug cannot be directly applied to the locally damaged mucosa, and the onset of effect is slow.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • An application of hydroxypropyl methyl cellulose in upper gastrointestinal tract mucous membrane damage nursing
  • An application of hydroxypropyl methyl cellulose in upper gastrointestinal tract mucous membrane damage nursing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Weigh 1 g of hydroxypropyl methylcellulose and 1000 g of purified water.

[0033] Add hydroxypropyl methylcellulose into purified water with a total water consumption of 40% under stirring, and continue stirring until the swelling is completely transparent;

[0034] Add the rest of the purified water and stir for 0.5h, that is.

Embodiment 2

[0036] Weigh 15 grams of hydroxypropyl methylcellulose and 1000 grams of purified water.

[0037] Add hydroxypropyl methylcellulose into purified water with a total water consumption of 40% under stirring, and continue stirring until the swelling is completely transparent;

[0038] Add the rest of the purified water and stir for 0.5h, that is.

Embodiment 3

[0040] Weigh 28 grams of hydroxypropyl methylcellulose and 1000 grams of purified water.

[0041] Add hydroxypropyl methylcellulose into purified water with a total water consumption of 40% under stirring, and continue stirring until the swelling is completely transparent;

[0042] Add the rest of the purified water and stir for 0.5h, that is.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
dynamic viscosityaaaaaaaaaa
Login to View More

Abstract

An application of hydroxypropyl methyl cellulose in upper gastrointestinal tract mucous membrane damage nursing is disclosed. The hydroxypropyl methyl cellulose can also be a hydroxypropyl methyl cellulose-containing composition comprising 1-28 parts by weight of hydroxypropyl methyl cellulose and 1000 parts by weight of purified water. A preparing method includes adding the hydroxypropyl methyl cellulose into the purified water the weight of which is 40% of the total weight of the purified water under stirring, stirring the mixture continuously until the hydroxypropyl methyl cellulose swells thoroughly and a clear solution is formed, adding the rest purified water into the mixture, and stirring the mixture until thorough dissolution. The hydroxypropyl methyl cellulose and the composition generate effects of film in an upper gastrointestinal tract. The generated film has mucous membrane adhesiveness so that functions of the film are sustainable.

Description

technical field [0001] The invention relates to the application of a substance with special efficacy, in particular to the application of hydroxypropyl methylcellulose in the care of upper digestive tract mucosal injury. Background technique [0002] The upper gastrointestinal tract consists of the oral cavity, pharynx, esophagus, stomach, and duodenum. Mouth: Consists of lips, cheeks, palate, teeth, tongue and oral glands. After the oral cavity is stimulated by food, the glands in the oral cavity secrete saliva, and the chewed food is mixed with saliva, and the amylase in saliva can partially decompose carbohydrates through the esophagus through the lubricating effect of saliva. Pharynx: is the common passage of the respiratory and digestive tracts. The pharynx can be divided into three parts, the nasopharynx (part), the oropharynx (part), and the hypopharynx (part) according to the passages with the nasal cavity, oral cavity and larynx. The main function of the pharynx ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/717A61K31/724A61P1/04A61P31/04A61P29/00
CPCA61K31/717A61K31/724A61P1/02A61K9/08A61K47/38A61P1/04A61K47/26A61K47/12A61K47/36A61K47/42A61K47/02A61K47/14
Inventor 高宇卜允利
Owner HEFEI JIUYAN MEDICINE TECH DEV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com