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A blood lipid-lowering compound based on squid swim bladder polypeptide and its preparation method

A compound and blood lipid-lowering technology, which is applied in food science, the function of food ingredients, and protein-containing food ingredients, can solve problems such as lowering blood lipids, affecting physical health, and increasing the burden on the liver, so as to reduce the content and improve blood micro-fat. Circulation, the effect of reducing cardiovascular disease

Active Publication Date: 2020-10-16
北京中科上医中医学研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The composition reduces blood lipids by promoting the decomposition of triglycerides and high-density lipoproteins by the liver, which increases the burden on the liver and will affect the health of the body in the long run

Method used

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  • A blood lipid-lowering compound based on squid swim bladder polypeptide and its preparation method

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Embodiment 1

[0017] A blood lipid-lowering compound based on squid swim bladder polypeptide, the ingredients and parts by weight are: 80-95 parts of squid swim bladder polypeptide, 10-15 parts of Panax notoginseng saponins, 0.0001-0.0002 parts of guaiacol, 1 part of fish oil ~10 parts, 0.5~2 parts of vitamin C and 0.0002~0.0006 parts of citrus lactone. The average molecular weight of swim bladder polypeptide is 550.0~750.0 Da, the content of glycine is 16.3~16.6%, the content of hydroxyproline is 7.7~8.1%, the content of alanine is 7.4~7.9%, and the content of proline is 6.8~ 7.1%, the content of glutamic acid is 6.6~6.9%, the content of arginine is 6.2~6.5%, the content of aspartic acid is 4.3~4.6%, and the content of arginine is 3.8~4.1%.

[0018] A method for preparing a blood lipid-lowering compound based on squid swim bladder polypeptide, the preparation steps are:

[0019] 1) Wash the squid swim bladder, homogenate, add 0.17~0.23mol / L Na according to the weight volume ratio of 1g:15...

Embodiment 2

[0024] A blood lipid-lowering compound based on squid swim bladder polypeptide, the ingredients and the most preferred parts by weight are: 90 parts of squid swim bladder polypeptide, 13 parts of Panax notoginseng saponins, 0.0001 part of guaiacol, 6 parts of fish oil, and vitamin C 1.3 parts and 0.0004 parts of bergamotide.

[0025] A method for preparing a blood lipid-lowering compound based on squid swim bladder polypeptide, the preparation steps are:

[0026] 1) Homogenized squid swim bladder and Na 2 HPO 4 -NaH 2 PO 4 The buffer solution (pH 6.0~7.5, concentration 0.2 mol / L) was mixed and homogenized according to the weight volume ratio of 1g:18ml, and then the pH value was adjusted to 6.5 to obtain the mixed solution;

[0027] 2) Raise the temperature of the mixture to 55°C, stir and preheat for 10 minutes, then microwave at 400 W for 15 minutes; add neutral protease and papain complex enzyme system (1:1, w / w) according to 2.3% of the raw material mass, The enzymati...

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Abstract

The present invention discloses a blood lipid lowering compound based on miichthys miiuy swimming bladder polypeptides and a preparation method thereof. The compound comprises the following ingredients in parts by weight: 80-95 parts of the miichthys miiuy swimming bladder polypeptides, 10-15 parts of radix notoginseng total saponins, 0.0001-0.0002 part of guaiacol, 1-10 parts of fish oil, 0.5-2 parts of vitamin C and 0.0002-0.0006 part of bergapten. Beneficial effects are as follows: the prepared compound is green and safe, free of toxic and side effects, low in molecular weight, easy for absorption and high in utilization rates, at the same time can supplement needs of users for amino acids, etc., lowers blood pressure, at the same time increases blood flow volumes of coronary arteries and brain blood vessels, improves blood microcirculation of heart and brain tissues, can effectively reduce contents of serum cholesterols and low density lipoproteins in human body, and reduces incidence of cardiovascular diseases. The preparation method uses a biological enzymolysis, and is simple in steps, high in efficiency and low in costs.

Description

technical field [0001] The invention relates to the field of health food, in particular to a blood fat-lowering compound based on squid swim bladder polypeptide and a preparation method thereof. Background technique [0002] Hyperlipidemia is a systemic disease, which refers to high total cholesterol (TC) and / or triglyceride (TG) or low high-density lipoprotein cholesterol (HDL-C) in the blood, which is called blood lipid in modern medicine abnormal. Lipids are insoluble or slightly soluble in water and must be combined with proteins to exist in the form of lipoproteins. Therefore, hyperlipidemia is also commonly referred to as hyperlipoproteinemia. Hyperlipidemia is a common and frequently-occurring disease of middle-aged and elderly metabolic diseases, and it is the main factor causing coronary heart disease, arteriosclerosis, cerebral thrombosis and cerebral hemorrhage. In recent years, due to the improvement of living standards, high-calorie foods in daily diet have gr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23L33/10A23L17/00A23L33/18
CPCA23V2002/00A23V2200/326A23V2200/3262A23V2200/30A23V2250/55
Inventor 王斌赵文浩赵玉勤潘欣
Owner 北京中科上医中医学研究院
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