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Erodible anhydrous polyethylene oxide film

A technology of polyethylene oxide and water film, which is used in the preparation of skin care preparations, medical preparations of inactive ingredients, and preparation of detergent mixture compositions

Active Publication Date: 2017-09-26
EVEREADY BATTERY CO INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Another problem is the sustained and prolonged release rate of PEO

Method used

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  • Erodible anhydrous polyethylene oxide film
  • Erodible anhydrous polyethylene oxide film
  • Erodible anhydrous polyethylene oxide film

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0124] Erodable water-free films prepared by solvent casting

[0125] Add the desired amount of A200V and stir until A200V was dissolved to make a fluid composition. To this clear solution was added DOW CORNING's Elastomer 9546 with stirring, followed by flexible resin. The solution is then cooled to room temperature and the support polymer is added with mixing PLUS Vinyl Acetate / Butyl Maleate / Isobornyl Acrylate Terpolymer over a period of about 15 minutes, after which the powdered PEO was slowly added until the PEO was completely dispersed in the mixture with few or no lumps. To this dispersion was added polyethylene glycol-200 with stirring for about 10 minutes, followed by the addition of 375 for about 10 more minutes. Additional isopropanol was added to adjust the viscosity to about 1200 cP to about 2000 cP.

[0126] A 1 / 8 inch thick stainless steel plate was fitted with a silicone treated release paper on the top side. Using a suitable scraper, pour the fluid...

Embodiment 22

[0142] Example 22. Solvent Casting Erodable Anhydrous Films Comprising PEO and Polyurethane

[0143] A solution of 18 grams of LUBRIZOL SP 80A-150 polyurethane polymer and 12 grams of LUBRIZOL SG 80A polyurethane polymer in 190 grams of tetrahydrofuran was prepared as mixture A. To 11 grams of mixture A was added a dispersion comprising 14.25 grams of polyethylene oxide particles having a particle size of less than 53 microns in 13.5 grams of tetrahydrofuran (mixture B). The resulting composition was mixed, poured into a frame and allowed to air dry for 40 minutes to evaporate the solvent. A pressure sensitive adhesive layer with an attached liner was placed on the film before the film was removed from the frame and further dried in an oven at 80°C for 24 hours. The PEO / polyurethane film contained 11% by weight polyurethane and 89% by weight PEO. When this procedure was repeated using 22 grams of Mixture A and Mixture B provided above, the resulting PEO / polyurethane film con...

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Abstract

An erodible anhydrous film useful in delivering active agents to a surface including keratinous surfaces, and hard or soft surfaces is disclosed. The erodible anhydrous film contains polyethylene oxide in combination with a support polymer, and optionally, other additives for skin care, fabric care, or hard surface cleaning. The erodible anhydrous film is useful when used as a comfort strip for enhancing shaving.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to US Provisional Application No. 62 / 057487, filed September 30, 2014, the contents of which are hereby incorporated by reference in their entirety. technical field [0003] In general, the present invention relates to anhydrous compositions and methods of forming erodible anhydrous polyethylene oxide membranes, erodable anhydrous membranes produced thereby and uses of said membranes. The erodible, water-free films can deliver active agents to substrates in a consistent and durable manner for a variety of applications. Background of the invention [0004] The background of the invention is most closely related to the field of shaving, but the invention is also applicable to other uses requiring delivery of active agents to substrates, such as delivery of therapeutic agents to keratinous surfaces (such as the surface of skin or hair) or delivery of cleansing agents delivered to the subs...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/86A61K8/39A61K8/02A61Q9/04A61Q9/02A61Q19/00
CPCA61K8/0216A61K8/39A61K8/86A61Q9/02A61Q9/04A61Q19/00C11D2111/12A61K8/8152A61K9/7007A61K47/32A61K47/34A61Q19/007A61Q19/08C11D3/3707C11D3/3757
Inventor J·A·史密斯G·克勒特R·梅塔R·麦科马克P·伯吉奥
Owner EVEREADY BATTERY CO INC