Full parallel lock phase photon counting detection mode based NIRS cerebral function imaging system

A photon counting and detection mode technology, which is applied in the fields of spectral diagnosis, diagnostic recording/measurement, medical science, etc., can solve the problems of unreliable high sensitivity and large dynamic range, and the inability to obtain signal-to-noise ratio measurement data, so as to avoid sampling Effects of signal distortion, time resolution improvement, and cost reduction

Active Publication Date: 2017-10-17
TIANJIN UNIV
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Problems solved by technology

Even the use of highly sensitive photomultiplier tubes (PMTs) and avalanche photodiodes (APDs) cannot reliably achieve the high sensitivit

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  • Full parallel lock phase photon counting detection mode based NIRS cerebral function imaging system
  • Full parallel lock phase photon counting detection mode based NIRS cerebral function imaging system
  • Full parallel lock phase photon counting detection mode based NIRS cerebral function imaging system

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Embodiment Construction

[0031] The technical solution of the present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments, and the described specific embodiments are only for explaining the present invention, and are not intended to limit the present invention.

[0032] A NIRS brain function imaging system based on a fully parallel phase-locked photon counting detection mode proposed by the present invention includes a source-detector fiber arrangement array unit, a modulatable LED light source unit, a detection unit, an FPGA, and a computer control and data processing unit. Its principle block diagram is as follows figure 1 shown, where:

[0033] (1) Modulable LED light source part: including a modulable LED light source module, a multi-channel square wave signal modulation module, 20 bundles of source optical fibers and a power supply module.

[0034] (1) Modulatable LED light source module: This part includes semiconductor ligh...

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Abstract

The invention discloses a full parallel lock phase photon counting detection mode based NIRS (Near Infrared Spectrum) cerebral function imaging system. The full parallel lock phase photon counting detection mode based NIRS cerebral function imaging system includes a modulating LED light source unit, a source-detection optical fiber arrangement array unit, a detection unit, an FPGA and a computer control and data processing unit; the modulating LED light source unit includes an LED light source module, a multi-channel square signal generator module, and 20 source optical fibers; the LED light source module includes 60 LEDs having three wave lengths and an LED light source drive circuit; the multi-channel square signal generator module outputs 60 square signals with different frequencies; the source-detection optical fiber arrangement array unit includes a source-detection optical fiber arrangement paster for arranging 20 light source points and 12 detection points, a plurality of optical fibers and a plurality of detection optical fibers; the detection unit includes 12 detection optical fibers, 12 PMT photon counter and 12 channel X 60 variable gate lock phase photon counting detection modules. The imaging system is high in sensitivity, is large in dynamic range, and is high in time resolution.

Description

technical field [0001] The invention belongs to the technical field of near-infrared brain function imaging, and specifically relates to a multi-channel, multi-wavelength phase-locked photon counting full-parallel detection mode based on different frequency square wave modulation LED coding excitations and a NIRS brain function imaging system established based on this mode. A source-probe configuration scheme for the detection of visual functional areas in the occipital region was proposed. Background technique [0002] The occipital lobe of the hindbrain (referred to as the occipital region), as the main visual area, is one of the key areas in the study of visual stimulation brain function (referred to as visual brain function) [1] . The in vivo imaging study of the occipital visual function area is of great significance: in the field of scientific research, visual brain functional imaging is an important part of the study of the brain's cognitive mechanism, and it is help...

Claims

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Application Information

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IPC IPC(8): A61B5/00
CPCA61B5/0075A61B5/4064A61B5/4076A61B5/4088A61B5/4094A61B5/7203
Inventor 高峰贺捷丁雪梅丁号赵会娟
Owner TIANJIN UNIV
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