Preparation method of self-repairing hydrogel type dressing material based on layer-by-layer assembly function

A layer-by-layer self-assembly and self-healing technology, applied in skin care preparations, pharmaceutical formulations, cosmetic preparations, etc., can solve the problems of mechanical properties decline, shorten the service life of materials, affect the normal use performance of materials, etc., and achieve easy operation. , good antibacterial properties, excellent self-healing properties
CN107375995AInactive Publication Date: 2017-11-24临沂市人民医院
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
临沂市人民医院
Publication Date
2017-11-24
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a preparation method of a self-repairing hydrogel type dressing material based on a layer-by-layer assembly function. The hydrogel dressing material is controllably constructed by selecting the optimal assembly elements, utilizing the advantages of a layer-by-layer assembly technology on constructing a gel membrane material, and adjusting the optimal assembly conditions (acid-base value, ion strength, solvent, etc.). Furthermore, based on the layer-by-layer assembly technology, target substances with different properties and performances can be assembled to the dressing material through many modes, and the target substances can be controllably released. The prepared dressing material has the following characteristics: (1) the dressing material has a strong dressing performance and excellent biocompatibility and thus is an ideal wet dressing material; (2) the dressing material has an excellent controlled release function and is capable of precisely releasing loaded drugs under specific incentive conditions; and (3) the dressing material has an excellent self-repairing performance and can repair damaged parts rapidly, the service life is prolonged, and the secondary damage caused by replacement is avoided.
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Description

technical field

[0001] The invention relates to a method for preparing a self-healing hydrogel dressing material based on layer-by-layer assembly functions. By screening the optimal assembly primitives and adjusting the optimal assembly conditions (pH, ionic strength, solvents, etc.) The controllable construction of the gel film material can improve the antibacterial performance of the material, greatly improve the service life of the dressing material, and reduce the secondary damage caused by replacement, which belongs to the technical field of biomedical materials. Background technique

[0002] A medical dressing is a protective covering over a wound to help control bleeding, prevent infection, and absorb secretions. Traditional wound dressings are mainly gauze, bandages, cotton, etc., which can provide wounds with layer-by-layer assembly of therapeutic drugs, stop bleeding, prevent water, electrolytes, and other foreign substances from stimulating, and accelerate wound h...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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