Antibacterial absorbable surgical suture and method for preparing same
A surgical suture and antibacterial technology, applied in the field of medical devices, can solve the problems of increasing the incidence of surgical site infection, increasing the economic burden of patients, and easy adsorption and hiding of bacteria, so as to avoid inflammation and wound infection, promote wound healing, and effectively Good for degradation and absorption
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
preparation example Construction
[0036] The preparation method of the antibacterial absorbable surgical suture thread of the present invention comprises prolamin dissolution, mixed oleic acid, preparation of silk-forming stock solution, preparation of silk and post-processing steps, the specific steps are as follows:
[0037] A. Dissolving gliadin: Add cereal gliadin into ethanol aqueous solution, stir until most of gliadin dissolves, and obtain gliadin mixture;
[0038] B. Mixed oleic acid: add oleic acid to the above prolamin mixture, stir at a constant temperature of 50-70°C at a speed of 500-700rpm / min until the solution is uniform and transparent, and a mixed solution is obtained;
[0039] C. Preparation of silk-forming stock solution: add chitosan to the above-mentioned mixed solution, stir at a speed of 500-700 rpm / min for 40-90 min at 60-70 ° C under heat preservation conditions, and then cool to room temperature at normal temperature and pressure. Obtain the silk stock solution;
[0040] D. Preparat...
Embodiment 1
[0049] 1. Under normal temperature and pressure, weigh 10g of zein, dissolve it in 50ml of 80% (about 43g, density 0.85932 g / ml) ethanol-water solution, stir with a glass rod until most of the zein dissolves , to obtain a zein mixture;
[0050] 2. Add 7ml of oleic acid (about 6.24g, density 0.891 g / ml) into the above-mentioned zein mixture, stir in a constant temperature magnetic stirrer at 50-70°C at a speed of 600rpm / min until the solution is uniform and transparent, and get Mixed liquid;
[0051] 3. Add 5g of chitosan to the above-mentioned mixed solution, stir at a constant temperature magnetic stirrer at a speed of 600rpm / min for 60min under the condition of 60-70°C heat preservation, then cool to room temperature under normal temperature and pressure to obtain silk stock solution;
[0052] 4. Put the above-mentioned silk-forming stock solution into the thread-forming device, and squeeze the thread-forming stock solution into an ice-water bath containing 10% by weight o...
Embodiment 2
[0055] 1. Under normal temperature and pressure, weigh 9g of wheat prolamin, dissolve it in 50ml of 89.8% (about 41.5g, density 0.82992 g / ml) ethanol-water solution, stir with a glass rod until most of the wheat alcohol dissolves Dissolving the protein to obtain the wheat prolamin mixture;
[0056]2. Add 8ml of oleic acid (about 7.12g, density 0.891 g / ml) into the above wheat prolamin mixture, stir in a constant temperature magnetic stirrer at 50-70°C at a speed of 500rpm / min until the solution is uniform and transparent, and get Mixed liquid;
[0057] 3. Add 10 g of chitosan to the above-mentioned mixed solution, stir at a constant temperature magnetic stirrer at a speed of 500 rpm / min for 90 min at a temperature of 60 to 70° C., and then cool to room temperature at normal temperature and pressure to obtain silk stock solution;
[0058] 4. Put the above-mentioned silk-forming stock solution into the thread-forming device, and squeeze the thread-forming stock solution into a...
PUM
Property | Measurement | Unit |
---|---|---|
concentration | aaaaa | aaaaa |
diameter | aaaaa | aaaaa |
diameter | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com