A kind of antibacterial hand sanitizer containing purslane and preparation method thereof

A technology of purslane and hand sanitizer, which is applied in the field of daily cleaning products, can solve the problems of low solubility, insignificant increase, and less research, and achieve the effects of increased content, good antibacterial activity, and optimized purification process

Active Publication Date: 2021-02-26
SHANDONG ZHUSHI PHARMA GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Purslane (scientific name: Portulaca oleracea L.) is an annual herb plant. The whole plant of purslane contains bactericidal and anti-inflammatory ingredients. Purslane contains antibacterial components. However, most of the current research work on the extraction of purslane focuses on the extraction and application of its polysaccharide components, and there are few related studies on its antibacterial components.
The inventor of the present application has found out a kind of method of extracting bacteriostatic component from purslane through research, but when applying the extracted bacteriostatic component in washing product, find that its solubility in water is very little, water The solubility increases with the increase of the external temperature, but the increase is not obvious

Method used

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  • A kind of antibacterial hand sanitizer containing purslane and preparation method thereof
  • A kind of antibacterial hand sanitizer containing purslane and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The steps of preparing antibacterial hand sanitizer in this example are as follows:

[0026] 1. Extract the antibacterial components of purslane

[0027] (1) Remove impurities from the whole herb of purslane, dry it at a constant temperature at 40-50°C until anhydrous, then pulverize and sieve to 50-60 mesh to obtain purslane powder;

[0028] (2) purslane powder is placed in the ethanol aqueous solution that contains hydrochloric acid volume concentration, the massfraction of the contained hydrochloric acid of control ethanol aqueous solution is 0.5%, the liquid-solid ratio of control ethanol aqueous solution and purslane powder is 5:1; use ultrasonic power of 125W to extract at 55°C to obtain ethanol extract;

[0029] (3) Concentrate the above extract under reduced pressure until it has no alcohol smell, add water to prepare a 9mg / ml crude extract solution, and absorb it through the macroporous resin D101 at a rate of 5.2BV / h. Wash the macroporous resin with water gr...

Embodiment 2

[0038] The steps of preparing antibacterial hand sanitizer in this example are as follows:

[0039] 1. Extract the antibacterial components of purslane

[0040] (1) Remove impurities from the whole herb of purslane, dry it at a constant temperature at 40-50°C until anhydrous, then pulverize and sieve to 50-60 mesh to obtain purslane powder;

[0041] (2) purslane powder is placed in the ethanol aqueous solution that contains hydrochloric acid volume concentration, the massfraction of the contained hydrochloric acid of control ethanol aqueous solution is 0.6%, the liquid-solid ratio of control ethanol aqueous solution and purslane powder is 6:1; extract with ultrasonic power 150W at 58°C to obtain ethanol extract;

[0042] (3) Concentrate the above-mentioned extract under reduced pressure until it has no alcohol smell, add water to prepare a 10mg / ml crude extract solution, and absorb it through the macroporous resin H-103 at a speed of 4BV / h, and use it after the crude extract ...

Embodiment 3

[0051] The steps of preparing antibacterial hand sanitizer in this example are as follows:

[0052] 1. Extract the antibacterial components of purslane

[0053] (1) Remove impurities from the whole herb of purslane, dry it at a constant temperature at 40-50°C until anhydrous, then pulverize and sieve to 50-60 mesh to obtain purslane powder;

[0054] (2) purslane powder is placed in the ethanol aqueous solution that contains hydrochloric acid volume concentration, the massfraction of the contained hydrochloric acid of control ethanol aqueous solution is 0.8%, the liquid-solid ratio of control ethanol aqueous solution and purslane powder is 8:1; extract with ultrasonic power 175W at 60°C to obtain ethanol extract;

[0055] (3) Concentrate the above extract under reduced pressure until it has no alcohol smell, add water to prepare a 12mg / ml crude extract solution, and absorb it through the macroporous resin D101 at a rate of 3.8BV / h. Wash the macroporous resin with water greate...

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Abstract

The invention provides a purslane-containing antibacterial hand sanitizer and a preparation method thereof, belonging to the technical field of daily cleaning products. The antibacterial hand sanitizer is made of the following raw materials in parts by weight: 6-10 parts of cocamidopropyl betaine, 4-8 parts of alkylphenol polyoxyethylene ether, and 3-5 parts of isopropyl palmitate , 1-3 parts of hyaluronic acid, 2-4 parts of sodium chloride, 2-5 parts of maltitol, 0.3-0.8 parts of purslane extract, 0.03-0.06 parts of glycyrrhizic acid, 70-90 parts of water. The hand sanitizer of the invention has better antibacterial and antibacterial effects, is safe and mild, and is relatively safe to human bodies.

Description

【Technical field】 [0001] The invention relates to the technical field of daily cleaning products, in particular to an antibacterial hand sanitizer containing purslane and a preparation method thereof. 【Background technique】 [0002] In daily life, people's hands are easily exposed to bacteria and dirt, and if they cannot be cleaned in a timely and effective manner, it may endanger their health. Especially for special occupational groups such as doctors and nurses, hand hygiene is even more important. As a new type of hand cleaning product, hand sanitizer appeared later than traditional cleaning products such as soap and soap, but it is popular because of its convenient use, saving time and water, avoiding cross-infection, easy storage, and reducing natural consumption. More and more consumers love it. However, the hand sanitizers currently on the market are still mainly chemical products, which add harmful ingredients such as bactericides and preservatives. After cleaning,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/63A61Q17/00A61Q19/10A61P31/02A61P31/04
CPCA61K8/345A61K8/63A61K8/97A61K2800/592A61K2800/82A61Q17/005A61Q19/10
Inventor 祝蕾程志鹏
Owner SHANDONG ZHUSHI PHARMA GRP CO LTD
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