Method for extracting silymarin

An extraction method, the technology of silymarin, applied in the direction of organic chemistry, etc., can solve the problems of increasing the extraction time cost and economic cost, the influence of silymarin extraction purity, and the failure of oil extraction, so as to save the softening and soaking process, ensure the extraction purity, Effect of increasing extraction rate and purity

Inactive Publication Date: 2018-02-16
内蒙古昶辉生物科技股份有限公司
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Problems solved by technology

The problem with this method is that after the milk thistle seeds are crushed, the oil cannot be completely extracted, which will have a certain impact on the subsequent extraction purity of silymarin; another technique is to shell the milk thistle seeds first, and then use water Silymarin is extracted from silyma

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  • Method for extracting silymarin
  • Method for extracting silymarin
  • Method for extracting silymarin

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Embodiment Construction

[0031] In view of the problems existing in the prior art, a method for extracting silymarin can avoid the influence of oil in silymarin seeds on the extraction of silymarin, and at the same time can improve the extraction rate of silymarin, which not only ensures the extraction purity but also improves the extraction efficiency.

[0032] In order to make the objectives, technical solutions and advantages of the present invention clearer, the present invention will be described in detail below with reference to the accompanying drawings and specific embodiments.

[0033] figure 1 It is the flow chart of the present invention to extract silymarin, such as figure 1 As shown, the following specific implementations are included.

[0034] Step S10, soaking milk thistle seeds in ethyl acetate for a predetermined time;

[0035] In this step, the silybum seed and 99% ethyl acetate are mixed and soaked for 1-2 hours according to the weight ratio of 1:(0.9-1.1), so that the silybum she...

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Abstract

The invention relates to a method for extracting silymarin. The method is characterized by comprising the following steps: soaking silybum marianum seeds in ethyl acetate for a preset time; taking thesoaked silybum marianum seeds out from the ethyl acetate, adding the soaked silybum marianum seeds into a hulling machine, and shelling the silybum marianum seeds; putting the silybum marianum shellinto an extraction tank of tank group type gradient extraction equipment, and adding ethyl acetate and a diluent into the extraction tank; performing gradient extraction on the silybum marianum shellto obtain a primary extracting solution of silymarin; concentrating the primary extracting solution to obtain a silybum marianum concentrated solution; and adding an alkaline aqueous solution into theconcentrated solution and performing stirring, then performing standing, precipitating and drying, and performing crushing and sieving so as to obtain the silymarin. According to the scheme providedby the invention, a gradient extraction mode is used, so that the extraction rate of the silymarin is increased, and the production energy consumption and the production cost are reduced.

Description

technical field [0001] The embodiments of the present invention relate to a production method, in particular to a production method of silymarin. Background technique [0002] Silymarin is a mixture of flavonoid lignans derived from the seeds of Silybum marianum. Its main components include flavonoids such as silibinin, isosilibinin, dehydrosilibinin, silymarin and silibinin. Silymarin has hepatoprotective and choleretic effects and is mainly used for the treatment of liver diseases. Secondly, it also has obvious anti-lipid peroxidation, anti-radiation, scavenging free radicals, anti-stomach ulcer and other effects. It has good effects in lowering blood lipids, preventing and treating atherosclerosis, preventing cerebral ischemia, and resisting platelet aggregation. Non-toxic, non-teratogenic and mutagenic. [0003] At present, there are two main extraction methods for silymarin, one is organic solvent extraction, and the other is alkali extraction and acid precipitation...

Claims

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Application Information

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IPC IPC(8): C07D407/04
CPCC07D407/04
Inventor 张成亮马亚琼赵永强徐旭贾洪涛
Owner 内蒙古昶辉生物科技股份有限公司
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