A traditional Chinese medicine capsule for treating coronary heart disease and preparation method thereof
A technology for Chinese medicine capsules and coronary heart disease, which is applied in the fields of medical formula, capsule delivery, cardiovascular system diseases, etc. It can solve the problems of unstable quality, low transfer rate of active ingredients, strong hygroscopicity of Chinese medicine products, etc., and prolong the disintegration time limit , easy to realize industrialization, and improve the effect of extraction and transfer rate
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Embodiment 1
[0032] Capsules were prepared according to the following formula and process, and the data are listed in Table 1 below.
[0033] Weigh the white peony root (paeoniflorin content is 4.4%), epimedium, and hawthorn in the formula amount and add it to the extraction tank, seal it, add water 10 times the total amount of medicinal materials, adjust the pH value of the solution to about 4 with a pH regulator, and add the formula Amount of excipients, soaked and extracted at 50°C for 2 hours, filtered, the filtrate was concentrated under reduced pressure to a viscous liquid, added 95% ethanol until the alcohol content was 65%, stood for 24 hours, filtered, the filtrate was concentrated under reduced pressure to obtain a thick paste, and the amount of red The ginseng powder is mixed and dried together, crushed into fine powder, passed through a 60-mesh sieve to obtain a dry powder of traditional Chinese medicine extract, which is directly filled into capsules, and an appropriate amount ...
Embodiment 2
[0039] Capsules were prepared according to the following formula and process, and the data are listed in Table 2 below.
[0040] Weigh the white peony (paeoniflorin content is 4.4%), epimedium and northern hawthorn in the formula amount and add them to the extraction tank, seal it, add water 12 times the total amount of medicinal materials, adjust the pH value of the solution to about 4 with a pH regulator, and add the formula Amount of excipients, soaked and extracted at 30°C for 8 hours, filtered, the filtrate was concentrated under reduced pressure to a viscous liquid, added 95% ethanol until the alcohol content was 70%, stood for 24 hours, filtered, the filtrate was concentrated under reduced pressure to obtain a thick paste, and the amount of red The ginseng powder is mixed and dried together, crushed into a fine powder, passed through a 60-mesh sieve to obtain a dry powder of traditional Chinese medicine extract, directly filled into capsules, and an appropriate amount of...
Embodiment 3
[0046] Capsules were prepared according to the following formula and process, and the data are listed in Table 3 below.
[0047] Weigh the white peony root (paeoniflorin content is 4.4%), epimedium, and hawthorn in the formula amount and add it to the extraction tank, seal it, add water 10 times the total amount of medicinal materials, adjust the pH value of the solution to about 4 with a pH regulator, and add the formula Amount of excipients were soaked and extracted at 40°C for 5 hours, filtered, the filtrate was concentrated under reduced pressure to a viscous liquid, added 95% ethanol until the alcohol content was 70%, stood for 24 hours, filtered, the filtrate was concentrated under reduced pressure to obtain a thick paste, and the amount of red ginseng was mixed with the formula The powders are mixed and dried together, crushed into fine powder, passed through a 60-mesh sieve to obtain dry powder of traditional Chinese medicine extract, directly filled into capsules, and an...
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