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Oral plaque revealing agent and preparation method thereof

A display agent and plaque technology, which is applied in material analysis by observing the influence of chemical indicators, and analysis by chemical reaction of materials, etc., can solve the problem of poor diffusion mobility, environmental pollution in the clinic, and inability to move colonies. Labeling and other problems, to achieve the effects of good stability, avoidance of pollution, and controllable conditions of the preparation method

Active Publication Date: 2021-01-05
LONGGANG DISTRICT CENT HOSPITAL OF SHENZHEN +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The purpose of the present invention is to overcome the above-mentioned deficiencies of the prior art, provide a kind of oral plaque revealing agent and its preparation method, to solve the problem that the existing oral plaque revealing agent causes the environmental pollution of the clinic and poor diffusion mobility. The technical problem of marking the trajectory of bacterial colony movement in space

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  • Oral plaque revealing agent and preparation method thereof
  • Oral plaque revealing agent and preparation method thereof
  • Oral plaque revealing agent and preparation method thereof

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preparation example Construction

[0032] On the other hand, the embodiment of the present invention also provides the preparation method of the oral plaque display agent of the embodiment of the present invention described above. The preparation method of the embodiment of the present invention comprises the following steps:

[0033] Step S01: Prepare organic phase components according to the organic phase components contained in the oral plaque display agent of the above-mentioned invention embodiment;

[0034] Step S02: Add the organic phase components or directly prepare the water phase components with the water phase components contained in the oral plaque display agent according to the embodiment of the present invention, and perform mixing and emulsification until the organic dyeing The agent is dispersed in the water phase in the form of organic solution particles.

[0035] Specifically, in the above step S01, the components contained in the organic phase are as described above for the oral plaque disp...

Embodiment 1

[0047] This embodiment provides an oral plaque display agent and a preparation method thereof. In this embodiment, the oral plaque display agent is an emulsion, and the organic phase of the emulsion includes organic dye phycoerythrin (sodium four-point fluorescein), ethanol, glycerol, peppermint oil, polyvinylpyrrolidone (PVP), methylol Sodium cellulose, and the content ratio of organic dye phycoerythrin (sodium four-point fluorescein), ethanol, glycerol, peppermint oil, polyvinylpyrrolidone (PVP), sodium hydroxymethyl cellulose is 1.5g phycoerythrin (Four-point fluorescein sodium): 15mL ethanol: 10mL glycerol: 5ml peppermint oil: 0.2mL polyvinylpyrrolidone (PVP): 0.5g sodium hydroxymethylcellulose; aqueous phase purified water.

[0048] A preparation method of the present embodiment oral plaque display agent is as follows:

[0049] Preparation of phase S11.A: In a 100ml Erlenmeyer flask, add 1.5g phycoerythrin (sodium four-point fluorescein), 15mL ethanol, 10mL glycerol, 5ml...

Embodiment 2

[0052] This embodiment provides an oral plaque display agent and a preparation method thereof. The oral plaque display agent of this embodiment is an emulsion, the organic phase of the emulsion includes petrolatum and erythrosine, and the mass content ratio of petrolatum and erythrosine is 100:2.5; the aqueous phase of the emulsion includes sodium phosphate, Calcium carbonate, sorbitol solution, polyvinyl alcohol, water, sodium hydroxymethyl cellulose and other components, and the content ratio of sodium phosphate, calcium carbonate, sorbitol solution, polyvinyl alcohol, water, sodium hydroxymethyl cellulose is : 0.76g sodium phosphate: 12.6g calcium carbonate: 55g70% sorbitol solution: 3g polyvinyl alcohol: 30ml water: 2g sodium hydroxymethylcellulose.

[0053] A preparation method of the present embodiment oral plaque display agent is as follows:

[0054] S21. Preparation of phase A: fully mix 100g of vaseline and 2.5g of erythrosine through a colloid mill to form a uniform...

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Abstract

The invention provides an oral cavity bacterial plaque display agent and a preparation method thereof, wherein the oral cavity bacterial plaque display agent comprises a water phase and an organic phase dispersed in the water phase, the organic phase contains an effective amount of an organic staining agent and an oil carrier supporting the organic staining agent, and the particle size of the organic phase is nano-scale. According to the present invention, the organic phase of the oral cavity bacterial plaque display agent is dispersed in the water phase in the form of the nano-scale micro-particles, such that the oral cavity bacterial plaque display agent can mark and display the bacterial plaque in the oral cavity of the patient, and the movement track of the bacterial plaque in the consulting room space can be marked because the dispersion movement of the organic phase is easily achieved due to the nano-scale particle size so as to achieve the infection control research during the oral cavity diagnosis and treatment; and with the preparation method, the organic phase can be dispersed in the forms of the nanoparticles and the micro-particles, and the stability of the oral cavitybacterial plaque display agent dispersion system can be ensured.

Description

technical field [0001] The invention belongs to oral pharmaceutical products, in particular to an oral plaque display agent and a preparation method thereof. Background technique [0002] The aerosol and fine dust produced in the process of oral clinical diagnosis and treatment seriously threaten the health of medical staff and patients. The aerosols carrying microorganisms can enter different parts of the respiratory tract according to their particle diameters; most of the particles with a diameter of 1-4 μm can directly reach the alveoli and cause infection. At present, the requirements and standards for air microbial quality (hereinafter referred to as air quality) are static, but in actual work, due to the use of various instruments, various diagnostic and treatment operations, and the flow of people, the air quality will be seriously affected, especially in the oral cavity. The diagnosis and treatment operations of the department are more specific and have a greater im...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/78
CPCG01N21/78
Inventor 高永波
Owner LONGGANG DISTRICT CENT HOSPITAL OF SHENZHEN