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Compound Chinese herbal medicine antibacterial mouthwash and preparation method thereof

A technology of mouthwash and Chinese herbal medicine, which is applied in the field of daily necessities, can solve the problems of black hairy tongue, metronidazole mouthwash taste change, decalcification of tooth surface, etc., and achieve the effect of inhibiting the killing effect

Inactive Publication Date: 2018-05-18
NANCHANG HANGKONG UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Most of the antibacterial mouthwashes currently on the market add ingredients such as metronidazole or hydrogen peroxide, but the use of metronidazole mouthwashes has adverse reactions such as taste changes and oral mucosal tingling, nausea, and vomiting. Long-term use of hydrogen peroxide can cause tooth surface decalcification And side effects such as black hairy tongue

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] In this example, a composite Chinese herbal antibacterial mouthwash is prepared from the following components by weight: 0.05g of wormwood extract; 0.05g of coral coral; 15g of absolute ethanol; 5g of glycerin; 1g of K12+DGL; EDTA-disodium 0.02g; ascorbic acid 0.01g; essence (mint) 0.01g; add deionized water to 100g.

[0046] A kind of preparation method of composite Chinese herbal medicine antibacterial mouthwash described in the present embodiment comprises the following steps:

[0047] (1) Dried wormwood, cut it into pieces and weighed it, added absolute ethanol according to the solid-to-liquid ratio of 1g:12ml, ultrasonically extracted for 3 hours, and then carried out suction filtration to obtain the ethanol extract of wormwood. Use a rotary evaporator to evaporate a large amount of ethanol at 45°C to obtain the wormwood extract (extract);

[0048] (2) According to the formula, dissolve the wormwood extract, grass coral extract and peppermint essence in absolute e...

Embodiment 2

[0050] In this example, a composite Chinese herbal antibacterial mouthwash is prepared from the following components by weight: 0.15g of wormwood extract; 0.15g of coral coral; 15g of absolute ethanol; 10g of glycerin; 1.1g of K12+DGL; 0.03g of disodium EDTA; 0.03g of ascorbic acid; 0.03g of essence (mint); add deionized water to 100g.

[0051] A kind of preparation method of composite Chinese herbal medicine antibacterial mouthwash described in the present embodiment comprises the following steps:

[0052] (1) Dried wormwood, cut it into pieces and weighed it, added absolute ethanol according to the solid-to-liquid ratio of 1g:12ml, ultrasonically extracted for 3 hours, and then carried out suction filtration to obtain the ethanol extract of wormwood. Use a rotary evaporator to evaporate a large amount of ethanol at 45°C to obtain the wormwood extract (extract);

[0053] (2) According to the formula, dissolve the wormwood extract, grass coral extract and mint essence in abso...

Embodiment 3

[0055] In this example, a composite Chinese herbal antibacterial mouthwash is prepared from the following components by weight: wormwood extract 0.15g; grass coral 0.15g; absolute ethanol 15g; glycerin 10g; K12+DGL 1.1g ; EDTA-disodium 0.03g; ascorbic acid 0.03g; essence (mint) 0.03g; add deionized water to 100g.

[0056] A kind of preparation method of composite Chinese herbal medicine antibacterial mouthwash described in the present embodiment comprises the following steps:

[0057] (1) Dried wormwood, cut it into pieces and weighed it, added absolute ethanol according to the solid-to-liquid ratio of 1g:12ml, ultrasonically extracted for 3 hours, and then carried out suction filtration to obtain the ethanol extract of wormwood. Use a rotary evaporator to evaporate a large amount of ethanol at 45°C to obtain the wormwood extract (extract);

[0058](2) According to the formula, dissolve the wormwood extract, grass coral extract and mint essence in absolute ethanol, and dissol...

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PUM

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Abstract

The invention belongs to the field of wash products and discloses compound Chinese herbal medicine antibacterial mouthwash and a preparation method thereof. The compound Chinese herbal medicine antibacterial mouthwash is prepared from, by mass, 0.1-0.5 part of artemisia vulgaris extract, 0.1-0.5 part of sarcandra glabra, 5-15 parts of 99.7% absolute ethyl alcohol, 5-10 parts of glycerin, 1.2 partsof K12+DGL, 0.04 part of EDTA-disodium, 0.01-0.05 part of ascorbic acid, 0.01-0.05 part of essence (mint) and the balance deionized water, wherein the total weight parts are 100 parts. By artemisia vulgaris with inhibition and killing effects on various viruses and bacteria and sarcandra glabra with heat clearing, detoxifying, swelling and pain relieving, antibacterial and anti-inflammation efficacies, quickly eliminating oral bacteria and cleaning areas which cannot be cleaned with brushes can be realized, and antibacterial and odor eliminating functions are achieved while safety and freeness of toxic and side effects are realized. The mouthwash has functions of oral cleanness keeping, harmful microorganism inhibiting and odor eliminating and is optimized in formula, easy to prepare andlow in cost.

Description

technical field [0001] The invention belongs to the field of daily necessities, and relates to a mouthwash and a preparation method thereof, in particular to a composite Chinese herbal medicine antibacterial mouthwash with two-in-one effects of sterilization and cleaning and a preparation method thereof. Background technique [0002] Oral health is closely related to physical health, and most oral diseases are related to bacteria, such as dental caries and oral ulcers. Dental caries is a bacterial disease caused by normal bacteria becoming conditional pathogenic bacteria due to oral dysbiosis. It can cause pulpitis and periapical periodontitis, and even cause inflammation of the alveolar bone and jaw, leading to complete destruction of the affected teeth; the secondary infection of dental caries can form lesions, and bacterial toxins can spread to the whole body through blood circulation. cause systemic disease. Oral ulcer is a relatively common cavity mucosal disease, mos...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/60A61K8/46A61Q11/00A61Q17/00
CPCA61K8/463A61K8/60A61K8/97A61K2800/82A61Q11/00A61Q17/005
Inventor 王精精赵李英钟劲茅邓芳张子涵
Owner NANCHANG HANGKONG UNIVERSITY