A kind of hydroboration method of ester
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- NANJING FORESTRY UNIV
- Publication Date
- 2022-04-19
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Abstract
Description
technical field
[0001] The invention relates to the technical field of hydroboration, in particular to a method for hydroboration of esters. Background technique
[0002] The conversion of esters to alcohols is an important reaction in organic synthesis. There are mainly three methods, one is the reaction of ester with hydride, the other is the reaction of metal catalyst with hydrogen, and the third is the reaction of metal catalyst to catalyze the hydrosilation or hydroboration of ester. Method 1 mainly uses LiAlH 4 and LiBH 4 . This method has obvious disadvantages, such as poor selectivity, easy to fire and so on. Method 2 also has many disadvantages, such as the need for high temperature and high pressure, poor selectivity, etc. X., Wang Y., Liu Y., Wang F., Shi L.; Lee K.H., Lin Z., Lv H., Zhang X. Org. Lett., 2015, 17, 454; Pritchard J., Filonenko G.A.; Putten R.V. , HensenE.J.M., PidkoE.A.Chem.Soc.Rev., 2015, 44, 3808; Biermann U., Friedt W., Lang S., Luhs W., M...